Senior AI Engineer, Provider & Oncology Innovation

US Remote

Role Description

This is a high-autonomy, high-agency position for a builder who thrives in ambiguity and wants to ship AI products that directly impact cancer care. You'll sit at the intersection of engineering, product, and design, working across all three modalities to ship products to customers. Your work will span two critical domains:

1. AI Products for Providers 

Design and ship AI-powered experiences for oncologists and clinical teams. This includes exploring conversational AI experiences, building agent-based workflows that help providers navigate managing patient care, and bringing new clinical AI products to market. You'll spend meaningful time with customers to deeply understand their workflows and uncover where AI can create transformative value.

2. Commercializing Natera's AI Foundation Models

You'll be the bridge between Natera's AI research lab and the launched product. Our team has developed proprietary models that need to be brought to market and into the hands of clinicians. You'll contribute to training and post-training of these models, build the serving infrastructure, shape the user experience, and own the end-to-end deployments of these products.

What You'll Do

  • Ship zero-to-one AI products end-to-end — from customer discovery and prototyping through production deployment and iteration
  • Build agentic AI systems — design and implement autonomous and semi-autonomous workflows using LLMs, tool-use, memory, and orchestration
  • Develop AI tools that improve efficiency across clinical operations, data extraction, manual workflows, and more
  • Commercialize AI research — partner with the AI lab to take proprietary models from research prototypes and into production
  • Contribute to model training and post-training — fine-tuning, evaluation, safety testing, and optimization of Natera's proprietary oncology models

What We're Looking For

Required

  • 5+ years of software engineering experience, with at least 2 years focused on AI/ML or LLM-powered products in production
  • Demonstrated ability to ship end-to-end — you've taken AI features or products from idea to production, ideally in a zero-to-one context
  • Strong full-stack engineering skills — proficiency in Python and modern web frameworks; you can build both the model pipeline and the user-facing product
  • Production experience with LLMs — fine-tuning, RAG, prompt engineering, agentic architectures, structured extraction, evaluation, and observability
  • High agency and autonomy — you don't wait for permission, detailed specs, or hand-holding. You unblock yourself, seek out the highest-impact work, and drive it to completion
  • Excellent communication — you can translate complex AI concepts for clinical and business stakeholders, and articulate a vision for what you're building and why

Preferred

  • Experience in healthcare, biotech, diagnostics, or pharma — especially oncology
  • Familiarity with clinical workflows, electronic health records, or provider-facing software
  • Track record of working in regulated environments (HIPAA, FDA, CLIA, CAP)
  • Background in or comfort with computational biology, genomics, or multimodal data (imaging, sequencing, clinical records)
  • Experience with AWS infrastructure, Kubernetes, MLflow, or similar ML platform tooling

Prior experience in a high-growth startup or zero-to-one product environment

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Remote USA

$125,000 - $156,300 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents. 

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

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