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Director of Commercial Operations

Pleasanton, California, USA HQ

The Director of Commercial Operations at 10x Genomics is a critical strategic leader, accountable for enabling the effectiveness, scalability, and success of our global commercial organization. This role ensures that people, processes, and platforms are aligned to maximize revenue growth and deliver consistent, world-class customer experiences. This leader will be responsible for designing and driving the programs, workflows, and technologies that equip commercial teams to succeed, through sales enablement programs, clear commercial processes such as forecasting and field execution, and the effective management of core systems such as CRM and marketing automation. The successful candidate will bring a customer-first mindset, strong commercial acumen, and proven expertise in both sales enablement and commercial systems management, with a clear emphasis on enabling high-impact execution and driving measurable business results.

Key Responsibilities

Strategic Leadership & Integration

  • Serve as a core member of the commercial team, shaping strategic direction and ensuring operational readiness to meet long-term and near-term revenue objectives.
  • Act as the principal integrator across Commercial, ensuring cohesion between systems, processes, enablement, and field execution.
  • Drive adoption of consistent processes, metrics, and reviews that establish discipline, accountability, and predictability in commercial performance.
  • Define clear field role descriptions and KPIs in partnership with Sales leadership; clarify ways of working across teams to optimize collaboration and efficiency.

Commercial Enablement & Operations

  • Build and scale sales enablement programs, including sales playbooks, content strategy/management, SOPs, field programs, and deal desk support.
  • Own funnel and forecast management disciplines, ensuring accuracy, transparency, and consistency across geographies and functions.
  • Partner with Sales, Marketing, and Support leaders to ensure teams are equipped with the resources, tools, and frameworks required for effective customer engagement.
  • Standardize and continuously improve commercial workflows to accelerate sales productivity and create consistent customer experiences.

Commercial Systems & Technology

  • Manage and maintain the GTM technology stack, including Salesforce.com, Marketo, Service Cloud, and related sales tools (lead gen, commerce, content platforms).
  • Oversee system governance and prioritize platform-related projects in collaboration with IT/productivity engineering teams.
  • Ensure systems are designed and configured to align with commercial workflows, enable scale, and deliver actionable insights.
  • Evaluate and deploy tools that enhance efficiency, content delivery, customer engagement, and sales execution.

Operational Excellence & Performance Management

  • Define, track, and report on key KPIs to measure the impact of enablement initiatives, sales execution, and technology adoption.
  • Use data and insights to continuously refine GTM strategies and identify opportunities for growth.
  • Lead ongoing business reviews with senior stakeholders to ensure strategy, performance, and operational priorities remain aligned.
  • Demonstrate the ROI of commercial operations initiatives through regular reporting and strategic recommendations.

Leadership & Collaboration

  • Build and lead a high-performing team, fostering a culture of accountability, collaboration, and continuous improvement.
  • Serve as a trusted advisor to commercial leadership on process, systems, and operational effectiveness.
  • Champion a “WE before ME” culture rooted in rigor, foresight, and customer impact.

Qualifications

  • 8+ years of experience in Commercial Operations, Sales Enablement, Revenue Operations, or related roles; strong preference for experience in life sciences, biotechnology, or scientific instrumentation.
  • 4+ years of leadership experience, including building and managing teams.
  • Demonstrated success in designing and scaling enablement programs (playbooks, content, deal desk, SOPs, pipeline/forecast management).
  • Proven expertise in CRM (Salesforce.com), marketing automation (Marketo), and service/support platforms (Service Cloud), with a strong grasp of broader sales tools and GTM tech stack integration.
  • Experience in process mapping, workflow optimization, or formal project/process management certification (e.g., PMP, Lean Six Sigma) is a plus.
  • Strong commercial acumen and experience supporting customer-facing teams in complex B2B/scientific sales environments.
  • Exceptional communication and stakeholder management skills; able to influence and drive alignment across functions.
  • Bachelor’s degree in Business, Marketing, Life Sciences, or related field required; MBA or advanced scientific/business degree preferred.

#LI-AR

Below is the base pay range for this full-time position.  The actual base pay will depend on several factors unique to each candidate, including one’s skills, qualifications, and experience.  At 10x, base pay is also just one component of the Company’s total compensation package.  This role is also eligible for 10x’s equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. During the hiring process, your 10x recruiter can share more about the Company’s total compensation package.

Pay Range

$197,700 - $267,500 USD

About 10x Genomics

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.

We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference. 

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.

10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

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