Back to jobs
New

Sr. Project Manager, Clinical Diagnostics Development

Pleasanton, California, USA HQ

About the Role

The Senior Project Manager, Clinical Diagnostics Development will lead the planning, execution, and control of critical, high-impact projects required to establish and sustain 10x Genomics' clinical diagnostics program and successfully transition novel single-cell and spatial diagnostic assays into a compliant clinical environment. This role ensures complex, cross-functional initiatives - including LIMS integration, QMS establishment, and analytical validation - are completed on time, on budget, and in strict adherence to CLIA, CAP, and other relevant regulatory standards.

The ideal candidate possesses a PMP certification, deep experience in project strategy, and technical familiarity with advanced molecular profiling technologies (NGS, single cell, spatial). They thrive in a hands-on, cross-functional environment, driving accountability across technical and compliance teams.

What you will be doing

Project Planning and Execution (Assay Transfer and CLIA Operations)

  • Support the planning and execution of technical transfer and analytical validation projects for new single-cell and spatial assays from assay development teams into the CLIA Laboratory, ensuring full traceability and documentation for verification/validation and that all regulatory requirements are met prior to go-live.
  • Develop and maintain detailed project schedules, resource plans, risk registers and work breakdown structures in partnership with 10x internal teams
  • Conduct thorough risk assessments and develop comprehensive mitigation strategies for all assigned projects, particularly those impacting quality and regulatory standing.
  • Manage change control processes, scope creep, and schedule deviations, proactively communicating potential impact to stakeholders and proposing mitigation strategies.
  • Ensure rigorous documentation and record-keeping throughout the project life cycle

Quality and Compliance Program Support

  • Collaborate with the quality team to drive the project plans for QMS establishment, ensuring all project documentation (e.g., facility documentation, equipment qualification, process SOPs) aligns with CLIA/CAP requirements and is audit-ready.
  • Collaborate with the information technology team to drive project plans for LIMS and the compute infrastructure required for clinical operations.
  • Facilitate the accreditation roadmap, scheduling and tracking deliverables required for CAP inspections, CLIA certification, and specific state approvals (e.g., New York State permit readiness).
  • Partner closely with Quality and Regulatory teams to ensure that project milestones incorporate necessary controls and compliance steps.

Cross-Functional Collaboration and Communication

  • Serve as the primary project communication hub, ensuring clear, consistent, and timely reporting of project status, milestones, risks, and dependencies to the project teams and executive stakeholders.
  • Organize and lead recurring project review meetings with cross-functional teams, including Laboratory Operations, Assay Development, Clinical Bioinformatics, Quality Assurance,  IT, and platform R&D teams to ensure alignment and accountability.
  • Foster strong working relationships with technical leads and subject matter experts to accurately capture project requirements and drive decision-making.
  • Guide 10x internal teams on project management best practices and principles.

To be successful, you will need:

  • Advanced degree (Master’s or Ph.D.) in a molecular biology, immunology, bioengineering, or related field.
  • Minimum of 7 years of professional experience managing complex projects in a regulated molecular diagnostics or life sciences company
  • Experience managing projects involving molecular diagnostics or Next-Generation Sequencing (NGS) platforms.
  • Proficiency with project management tools (e.g., Microsoft Project, SmartSheet, Jira) and collaboration platforms.

Additionally, we'd like to see:

  • Project Management Professional (PMP) certification or equivalent qualification (e.g., Lean Six Sigma).
  • Strong understanding of regulated diagnostic product development (e.g., CLIA, CAP, ISO 13485 or 21 CFR Part 820) and documentation control.
  • Experience with LIMS implementation, integration, or major upgrade projects.

It would be advantageous if you had:

  • Strong analytical skills and the ability to translate complex technical requirements into actionable project plans.
  • Excellent written and verbal communication skills, capable of effectively interacting with scientific, technical, and executive audiences.
  • Exceptional organizational skills, attention to detail, and a structured approach to problem-solving.
  • Proven ability to lead and manage cross-functional teams without direct reporting authority.
  • Proficiency in change management principles.
  • Driven, thoughtful, and ambitious, with a high sense of ownership and urgency to build new, high-quality, and compliant capabilities.

Below is the base pay range for this full-time position.  The actual base pay will depend on several factors unique to each candidate, including one’s skills, qualifications, and experience.  At 10x, base pay is also just one component of the Company’s total compensation package.  This role is also eligible for 10x’s equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. During the hiring process, your 10x recruiter can share more about the Company’s total compensation package.

Pay Range

$151,100 - $204,500 USD

About 10x Genomics

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.

We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference. 

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.

10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

LI Image    Twitter Icon

Apply for this job

*

indicates a required field

Resume/CV*

Accepted file types: pdf, doc, docx, txt, rtf

Cover Letter

Accepted file types: pdf, doc, docx, txt, rtf

Select...
Select...
Select...

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in 10x Genomics’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

Select...
Select...
Race & Ethnicity Definitions

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Select...

Voluntary Self-Identification of Disability

Form CC-305
Page 1 of 1
OMB Control Number 1250-0005
Expires 04/30/2026

Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

  • Alcohol or other substance use disorder (not currently using drugs illegally)
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
  • Blind or low vision
  • Cancer (past or present)
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or serious difficulty hearing
  • Diabetes
  • Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
  • Epilepsy or other seizure disorder
  • Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
  • Intellectual or developmental disability
  • Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
  • Missing limbs or partially missing limbs
  • Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
  • Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
  • Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
  • Partial or complete paralysis (any cause)
  • Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
  • Short stature (dwarfism)
  • Traumatic brain injury
Select...

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.