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Senior Research Scientist

San Carlos, CA

$100,000–130,000 base salary
(5 days/Onsite)

About The Role

Aequita Bioworks is a biotechnology company leveraging artificial intelligence to pioneer novel monoclonal antibody therapies. Join our innovative team focused on advancing therapeutic antibodies to address skeletal muscle loss during weight loss.

Application Requirements:

  • Your application must include a transcript in order to be considered

Key Responsibilities:

  • Conduct and analyze experiments to evaluate lead candidates’ effects on muscle metabolism, differentiation, atrophy, hypertrophy, and contraction.
  • Support the development of in vitro assays (e.g., qPCR, immunostaining, western blotting, ELISA) to study muscle cell activities in collaboration with senior team members.
  • Assist in evaluating therapeutic potential of novel targets using in vitro or pre-clinical models of obesity.
  • Execute functional assays (e.g., luciferase reporter, kinase activity, phosphorylation analysis) and utilize fluorescence/luminescence-based readouts (HTRF, AlphaScreen).
  • Collaborate with CROs under guidance to assess drug candidates in in vivo assays, including PK/PD and efficacy studies.
  • Maintain detailed electronic lab records and adhere to documentation standards.
  • Contribute to data interpretation and presentations for internal teams and reports for senior management.
  • Assist in drafting technical content for patents, IND applications, and regulatory submissions.

Other Responsibilities

This job description is not intended to be all-inclusive. From time to time you may be required to perform other related duties as assigned to meet operational needs.

Who You Are:

  • PhD in Molecular Biology, Biochemistry, or related field (0–2+ years industry experience) or Master’s degree with 5+ years of relevant experience or Bachelor’s degree with 7+ years of relevant experience.
  • Hands-on expertise in mammalian cell culture, including primary cell culture and differentiation.
  • Hands-on experience with 3D cell culture systems, organoid generation, or tissue engineering (skeletal muscle organoids preferred).
  • Proficiency in biochemical/cellular assays: immunoblotting, ELISA, kinase activity, and phosphorylation analysis.
  • Familiarity with in vitro models of muscle metabolism, atrophy, or hypertrophy.
  • Experience with assay readouts: colorimetric, luminescent, fluorescent (HTRF preferred).
  • Strong organizational skills and ability to thrive in a collaborative, fast-paced environment.
  • Excellent communication skills (written and verbal) in English.

Nice to Haves:

  • Experience with RNA sequencing, murine models, or high-resolution respirometry.
  • Exposure to drug discovery workflows (e.g., IND/NDA processes).
  • Prior work in biotech startups or muscle biology research.
  • Peer-reviewed publications in relevant fields.

Why Join Us?

  • Contribute to groundbreaking therapies in a dynamic, AI-driven environment.
  • Collaborate with cross-functional teams of scientists, AI specialists, and drug developers.
  • Opportunities for professional growth in a mission-driven startup.

Details:

  • This is an in-person role in San Carlos, CA
  • The compensation range for this role is $100,000–130,000 base salary

Life at Bioworks: Where Science Meets Culture 

Your Well-Being, Our Priority

  • Health Coverage- Medical, Dental, Vision insurance to keep you at your best!
  • Financial Wellness- 401(k) with generous company matching, plus fully covered life insurance. Ideal for those at every stage of their career journey, who value forward thinking financial security.

Balance and Recharge

  • Unlimited PTO-Rest, recharge, and never feel guilty about it! We trust you to know when to step away and come back stronger.

Fuel for Innovation

  • Daily Door Dash Delight- Company funded lunch everyday to brighten your noontime and keep you energized. Just one of the ways we are looking out for you.

Community & Culture 

  • Connected by culture- Enjoy team lunches, casual office hangouts, offsite outings, and social events that build camaraderie and bring science to life. We believe in nurturing not just your brain, but your whole body outside of the office. 
  • Mission Driven Impact- Be part of meaningful biotech breakthroughs. Your work will genuinely shape the future of science, and we will make sure to acknowledge it; a hypergrowth team that moves fast and builds with purpose!

Growth on Your Terms

  • Competitive Compensation and Equity- We match your contributions with a top-tier rate and a slice of ownership in the company.. Aligning your success with ours!

Equal Opportunity Employer

We are proud to be an equal opportunity workplace who prohibits discrimination and harassment of any kind. We celebrate diversity and are committed to creating an inclusive environment for all employees regardless of race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. We provide a work environment free of discrimination and harassment. All employment decisions are based on business needs, job requirements, and individual qualifications without regard to race, color, religion, sex, gender identity or expression, sexual orientation, national origin, disability status, protected veteran status, or any other protected characteristic as outlined by federal, state, or local laws.

We welcome all with a drive to work, and a curiosity to learn. We are here to build and be a part of science encompassing the full power and possibility for breakthrough innovation! 

To view our current job openings and apply, please visit our job portal. If you think you have what it takes but don't see a job fitting your skillset email us at recruiting@aequitabioworks.com.

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