Back to jobs
New

Manufacturing Hardware Engineer / Life Cycle Engineer

Fremont, California

At Alamar, we are passionate about enabling our customers to make scientific discoveries that translate into clinical outcomes and benefit patients. Our team is growing quickly as we develop innovative approaches to measure critical protein biomarkers from liquid samples that can enable the earliest possible detection of disease. We believe the next frontier in biology is enabled by measuring proteins at higher sensitivity in highly multiplexed assays at the push of a button, which is something only Alamar can do. As we build our team, we seek collaborative, driven, intellectually curious people committed to solving complex challenges. Our culture rewards accountability and cross functional teamwork because we believe this enables the kind of breakthrough thinking that will accelerate our mission.

We are seeking a hands-on, detail-oriented Hardware Engineer / Life Cycle Engineer to support automated bioassay platforms and maintain production processes, systems and machinery to ensure efficient, quality product manufacturing. Candidate should have a strong focus on Hamilton liquid handling systems used in complex bioconjugation workflows. This role is critical to ensuring instrument reliability, minimizing downtime, and supporting manufacturing through effective troubleshooting, maintenance, and lifecycle management. The ideal candidate combines technical depth with strong problem-solving skills and thrives in a fast-paced, dynamic environment.

Core Responsibilities

  • Perform advanced troubleshooting on Hamilton liquid handling systems supporting complex bioconjugation assays, including root cause analysis and issue resolution.
  • Execute and document routine maintenance, calibration, and repair of Hamilton instruments to ensure optimal performance and compliance.
  • Lead and support root cause investigations for process deviations, equipment failures, and manufacturing issues; implement corrective and preventive actions (CAPA).
  • Develop, maintain, and track preventive maintenance (PM) schedules across automation platforms and manufacturing equipment.
  • Able to safely perform minor interventions on liquid handling systems with simple tools.
  • Provide feedback to Engineering Team on equipment and automation design improvements to enhance manufacturability, reliability, and serviceability.
  • Serve as technical liaison with automation vendors and service providers, supporting FAT/SAT, service coordination, and spare parts strategy.
  • Author, review, and maintain equipment qualification documentation including Installation Qualification (IQ), Operational Qualification (OQ), and Performance Qualification (PQ).
  • Provide real-time support to manufacturing by triaging issues, coordinating cross-functional responses, and ensuring minimal disruption to operations.
  • Collaborate with process development, quality, and manufacturing teams to improve system robustness and assay performance.
  • May author new standard operating procedures (SOPs) and provide training to operations team.
  • Support lifecycle engineering activities, including equipment onboarding, validation, upgrades, decommissioning, and continuous improvement initiatives.
  • Maintain organized lab environments, including basic lab operations, inventory tracking, calibration schedule and equipment readiness.
  • Communicate effectively across teams, providing clear documentation, status updates, and technical insights.

Required Qualifications

  • Bachelor’s degree in Engineering (Mechanical, Biomedical, Electrical, or related field) or equivalent experience.
  • 2–5+ years of experience in life cycle engineering, hardware engineering, or automation support in a laboratory or manufacturing setting.
  • Hands-on experience with Hamilton liquid handling systems (e.g., STAR, VANTAGE) strongly preferred.

Preferred Skills and Attributes

  • Strong troubleshooting and diagnostic skills in automated systems and lab instrumentation.
  • Experience with bioconjugation assays or similar complex bioanalytical workflows is highly desirable.
  • Familiarity with equipment lifecycle management and GMP environments.
  • Experience drafting and managing IQ/OQ/PQ documentation.
  • Knowledge of preventive maintenance systems and scheduling tools.
  • Strong critical thinking and structured problem-solving abilities.
  • Ability to work under pressure and manage multiple priorities in a fast-paced environment.
  • Excellent communication and documentation skills.
  • Collaborative mindset with a strong sense of ownership and accountability.
  • Experience in regulated environments (GMP, GLP, or ISO).
  • Exposure to CAPA, deviation management systems, and change control processes.
  • Basic programming or scripting experience for automation platforms is a plus.

Work Environment & Physical Requirements

  • Hands-on laboratory and manufacturing floor environment.
  • Ability to lift and handle laboratory equipment and consumables as needed.
  • May require occasional off-hours or weekend support for critical troubleshooting.
  • Physical capability to move within office and lab environments and occasionally lift up to 25 lbs.

The base salary range for this full-time position is $125,000 - $145,000 + bonus + equity + benefits. Our salary ranges are determined by work location, job-related skills, experience, and relevant education or training. The ranges displayed on each job posting reflect the minimum and maximum target for new hire salaries but are subject to change if the leveling of the role is adjusted. Your recruiter can share more about the specific salary range during the hiring process. 

Create a Job Alert

Interested in building your career at Alamar Biosciences? Get future opportunities sent straight to your email.

Apply for this job

*

indicates a required field

Resume/CV*

Accepted file types: pdf, doc, docx, txt, rtf

Cover Letter

Accepted file types: pdf, doc, docx, txt, rtf

Education

Select...
Select...
Select...
Select...
Select...

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in Alamar Biosciences’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

Select...
Select...
Race & Ethnicity Definitions

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Select...

Voluntary Self-Identification of Disability

Form CC-305
Page 1 of 1
OMB Control Number 1250-0005
Expires 04/30/2026

Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

  • Alcohol or other substance use disorder (not currently using drugs illegally)
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
  • Blind or low vision
  • Cancer (past or present)
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or serious difficulty hearing
  • Diabetes
  • Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
  • Epilepsy or other seizure disorder
  • Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
  • Intellectual or developmental disability
  • Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
  • Missing limbs or partially missing limbs
  • Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
  • Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
  • Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
  • Partial or complete paralysis (any cause)
  • Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
  • Short stature (dwarfism)
  • Traumatic brain injury
Select...

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.