Senior Scientist, Cryogenic Electron Microscopy

Our Mission

Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.

For more information, see our website at altoslabs.com.

Our Value

Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission.

Diversity at Altos

We believe that diverse perspectives are foundational to scientific innovation and inquiry. At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment.

What You Will Contribute To Altos

Responsibilities

• Contribute to Electron Microscopy Workflows for both SEM and TEM experiments.
• Execute routine TEM experiments, including Single Particle Analysis and cryo-ET
  • Including but not limited to:
    • Grid preparation and sample optimization
    • TEM SPA and Tomography data collection
    • TEM SPA and Tomography image processing
  • Optimize the performance and uptime of TEM instruments, including preventative maintenance and management of service contracts.
  • Process data and implement workflows for correlative EM imaging.
  • Ensure equitable access for the Altos community and help with the research, design, and implementation of imaging modalities.
  • Consult on structural biology project design and execution strategies, including in the interpretation of data.
  • Interface with the IT team to ensure data transfer, storage, and integrity.
  • Collaborate broadly with the scientific community.
  • Keep up-to-date with the latest research in the field and identify new areas of investigation.

Who You Are

Minimum Qualifications

• PhD in Structural Biology or related field.
• 6+ years of experience in industry, demonstrating structural biology skills in a rapid-pace environment.
• Experience with modern Correlated Light and Electron Microscopy techniques and data processing
• Experience with Fluorescence Microscopy at room and cryogenic temperatures
• Strong track record of research excellence in modern Electron Microscopy modalities.
• Excellent analytical skills.
• Experience with cryoSPARC, ChimeraX, ISOLDE
• Ability to work well as part of a team.
• Rigorous documentation standards.
• End-to-end data management experience.
• Willingness to execute an industrial-style facility (EM as a service, limited user interaction with microscopes).
• Excellent written and verbal communication skills.
• Experience with Linux

Preferred Qualifications

• Experience with Amira, IMOD, WarpEM, Relion and other software packages.
• Proficiency with Python, basic shell scripting
• Compute infrastructure maintenance experience

The salary range for Redwood City, CA:

• Senior Scientist I, Scientific Technologies: $197,000 - $258,000

Exact compensation may vary based on skills, experience, and location.

For UK applicants, before submitting your application:

- Please click here to read the Altos Labs EU and UK Applicant Privacy Notice (bit.ly/eu_uk_privacy_notice)
- This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment.

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What We Want You To Know

We are a culture of collaboration and scientific excellence, and we believe in the values of inclusion and belonging to inspire innovation.

Altos Labs provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. 

This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training. 

Altos currently requires all employees to be fully vaccinated against COVID-19, subject to legally required exemptions (e.g., due to a medical condition or sincerely-held religious belief).

Thank you for your interest in Altos Labs where we strive for a culture of scientific excellence, learning, and belonging.

Note: Altos Labs will not ask you to download a messaging app for an interview or outlay your own money to get started as an employee. If this sounds like your interaction with people claiming to be with Altos, it is not legitimate and has nothing to do with Altos. Learn more about a common job scam at https://www.linkedin.com/pulse/how-spot-avoid-online-job-scams-biron-clark/