Contract Senior Research Associate, Analytical Development

South San Francisco

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients. 

The Alumis team is seeking a highly motivated Contract Sr. Research Associate of Analytical Development to join our dynamic small molecule analytical group. The successful candidate will use their knowledge, experience, and skills to support analytical development activities to advance Alumis drug candidates through the clinical phases to commercial products.

 

RESPONSIBILITIES

  • Under direct supervision, execute in-house analytical laboratory activities, such as analytical method development, sample analysis, and data reporting.
  • Operate, maintain, and troubleshoot analytical laboratory instrumentation as needed to execute assigned laboratory experiments.
  • Accurately document laboratory experiments and results in an electronic laboratory notebook.
  • Support outsourced analytical testing activities as needed, such as analytical method development, method transfers and validations, sample and reference material management, and release and stability testing.
  • Review CMO/CTL analytical data (in-process, release, and stability data) for accuracy and completeness, and effectively communicate data errors and gaps to supervisor.

 

THE IDEAL CANDIDATE

  • BS or MS in chemistry or pharmaceutical sciences with minimum 3 years of experience in an analytical laboratory environment.
  • Understanding of the basic principles of analytical method development, validations, and troubleshooting.
  • Direct experience with small molecule analytical techniques used for clinical phase drug substances and drug products, such as UPLC/HPLC, LC-MS, GC, KF, UV/Vis, IR, particle size analysis, dissolution testing, DSC, TGA, and XRPD.
  • Experience with reviewing GMP analytical data generated at CMOs and CTLs.
  • Self-motivated and driven to complete assigned tasks in a timely manner to advance the project pipeline.
  • Strong organizational, communication, and collaborative skills.
  • Working knowledge of ICH, cGMP, and regulatory requirements for small molecule drug substances and drug products.

 

This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday.*  At this time we are not considering remote applicants.

Contractor perks include:

  • Free access to Genentech Bus & Ferry Share program
  • Free onsite gym and a kitchen stocked with yummy snacks and drinks!

We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.

*Lab Personnel are generally onsite 4-5 days/week.

 

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