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Senior Product Operations Manager

San Francisco, CA

The Problem

Severe mental illness affects over 15 million adults in the United States. Schizophrenia. Schizoaffective disorder. Bipolar I. Treatment-resistant depression. These are the conditions the rest of healthcare has systematically failed to build for.

What makes this problem different from most of healthcare is that the tools to solve it do not exist. The clinical protocols, the measurement science, the precision medicine, the technology to deliver coordinated longitudinal outpatient care for this population. None of it has been built. This is a frontier problem, and it requires frontier science and care delivery to solve.

We are developing all of it. The care, the science, the technology.

Who We Are

Amae Health is a Series B, venture-backed Public Benefit Corporation delivering specialty outpatient care for people with severe mental illness through high-acuity, in-person clinics nationwide.

Our integrated model brings psychiatry, therapy, primary care, dietitians, and community support together under one roof. Leading health systems—including NewYork-Presbyterian, Cedars-Sinai, Mass General Brigham, Novant Health, and CommonSpirit—collaborate with us to expand this level of care.

Alongside care delivery, we are building the science and technology the field has long lacked—proprietary clinical protocols, novel measurement, and an AI-driven data platform designed for severe mental illness.

The impact: fewer hospitalizations, greater stability, and more people living meaningful lives in their communities.

The Team

We are clinicians, operators, technologists, and scientists who chose Amae because the problem is hard and the stakes are real. We are not interested in incremental improvements to a broken system—we are redefining it.

Every function—finance, product, people, growth, technology—exists to serve one goal: better outcomes for the people we care for.

The Role

Product is core to how we scale care—and how we get better outcomes for patients.

As our Senior Product Operations Manager, you’ll own how the product actually gets delivered, adopted, and improved in the real world. You’ll sit at the center of Product, Engineering, and Clinical teams, turning strategy into execution.

This is a high-ownership, high-ambiguity role. You won’t just support the system—you’ll build it.

What You'll Do

Drive Product Launch & Rollout

  • Own end-to-end execution of product launches—from rollout planning to go-live
  • Build scalable playbooks that ensure features land effectively across clinics

Ensure Adoption in the Field

  • Translate product into practice—design training, materials, and workflows that clinicians actually use
  • Run live sessions and ensure teams are confident using new tools

Build Operational Infrastructure

  • Create and maintain clear documentation across features, workflows, and systems
  • Establish the operating rhythms that keep Product, Engineering, and Clinical aligned

Be the Execution Engine

  • Own cross-functional coordination and push work across the finish line
  • Bring structure to ambiguity—prioritize, unblock, and deliver

Close the Feedback Loop

  • Manage intake and triage of product feedback and support tickets
  • Turn real-world insights into actionable inputs for Product and Engineering

Do What It Takes

  • We’re a startup—no job is too small
  • You’ll step in wherever needed to move the work forward

What You'll Have

  • 5+ years in Product Operations, GTM, or similar execution-heavy roles
  • Proven track record of launching products and driving adoption
  • Strong systems thinker—you’ve built processes that scale across teams
  • Exceptional communicator—you can translate between engineers, clinicians, and operators
  • Experience managing feedback loops, support workflows, or ticket triage
  • Comfortable operating in ambiguity—you create clarity where none exists
  • High urgency and ownership—you move fast and finish what you start
  • Fluency with AI tools to increase speed and leverage
  • Deep alignment with our mission to improve mental health care
  • Able to work in-person from our San Francisco HQ

What We're Building

Most healthcare companies ask you to optimize an existing system. We're building one that has never existed.

  • A national care model designed for the highest-acuity patients in behavioral health.
  • Precision medicine for severe mental illness, using multimodal clinical, behavioral, and social data to personalize treatment.
  • A clinical operating system that integrates longitudinal data, real-time patient signals, and purpose-built tools into a single decision layer.
  • New science and measurement frameworks to define what real outcomes look like in SMI.
  • A health-system partnership model proving coordinated SMI care can work at scale.

Why This Role Matters

Every product we ship directly impacts patient care. If we get this right:

  • Clinicians work more effectively
  • Patients receive better care
  • We scale faster without breaking

You’re not just improving a product—you’re helping build a system that changes lives.

Compensation & Benefits

Amae Health is committed to fair and equitable compensation practices. Compensation includes a base salary of $155,000- $175,000 (based on level & experience) plus equity ownership, giving you a meaningful stake in Amae's growth. Total compensation includes comprehensive medical/dental/vision, unlimited PTO, parental leave, and programs built around employee well-being. We’ll share specifics during the interview process.

Amae Health is building the care platform, the precision medicine, and the frontier science that severe mental illness has never had. If you want to be part of creating something this hard and this important, something that has never been done, we'd like to talk.

What We Value

We center care in all we do. Empathy is not a brand value. It’s how we make clinical decisions, build products, and treat each other.

We challenge convention. The existing system is the problem. We question it, we test alternatives, and we move with urgency when something works.

We take the work seriously, not ourselves. High standards and humanity are not in tension. We hold a hard bar for quality while leaving room for humor and levity.

Your job isn’t done until the job is done. We close gaps, we follow through, and we don’t hide behind titles or org charts.

We win together and fail together. We own outcomes as a team. We learn fast. We don’t do blame.

We hustle with humility. Speed matters. So does integrity. We assume best intent and stay grounded in the mission.

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