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Senior Director, Market Insights

Cambridge, MA

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).

Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.

The Opportunity

The Senior Director, Market Insights is a highly visible, enterprise-level leadership role responsible for defining and driving the end-to-end insights strategy to support U.S. commercialization and global expansion. The Senior Director will serve as the strategic owner of the insights function, ensuring that market intelligence, analytics, and evidence generation are fully integrated into corporate decision-making across the product lifecycle.

Reporting into the Vice President, Commercial Operations, the Senior Director will act as a key advisor to commercial and executive leadership, shaping commercial strategy through forward-looking insights that inform launch readiness, lifecycle management and portfolio prioritization. This role requires the ability to operate at both a strategy and operational level, building scalable capabilities and frameworks to support a multi-asset, multi-market organization.

Responsibilities

  • Define and own the enterprise-wide market insights strategy, aligning U.S. and ex-U.S. perspectives to support global commercialization and long-term portfolio growth, ensuring readiness across multiple markets and stakeholder groups
  • Lead and execute market research projects influencing key decisions related to product launch strategy, lifecycle planning, new product planning, and as necessary, key market access strategies; ensure project deliverables are actionable, archived, and accessible
  • Lead cross-functional integration of insight, ensuring alignment across Marketing, Medical, Market Access, Regulatory, R&D, and Executive Leadership to support decision-making
  • Build and scale the market insight’s function, including defining operating models, processes, tools, and governance to support increasing organizational complexity
  • Oversee and evolve global competitive intelligence strategy, ensuring proactive identification and ongoing communication of market shifts, competitive threats, and strategic opportunities
  • Partner with Business Development (BD) colleagues to rapidly build market assessments, competitive landscape modeling, value creation theses, and financial modeling to facilitate executive decision-making
  • Drive development of advanced analytics capabilities, including integration of primary research, real-world data, and secondary data sources into a cohesive insight ecosystem
  • Establish KPIs and measurement frameworks (customer engagement, brand tracking, etc.) to evaluate commercial effectiveness and inform ongoing strategic adjustments
  • Lead external partnerships and vendor strategy, including selection, governance, and optimization of research and analytics partners
  • Develop and mentor future capabilities, including team build-out as the organization scales
  • Lead insights efforts with a focus on post-bariatric hypoglycemia (PBH), Wolfram syndrome, progressive supranuclear palsy (PSP), and amyotrophic lateral sclerosis (ALS)

Required Qualifications

  • Bachelor’s degree required; advanced degree (PhD, MD, PharmD, or MBA) preferred
  • 12+years of experience in pharmaceutical or biotech market research, insights, or analytics, with increasing levels of responsibility
  • Proven experience generating insights across the product lifecycle, including early-stage development, launch, and post-launch optimization
  • Demonstrated expertise in competitive intelligence, including conference coverage and strategic synthesis of competitor activity
  • Strong understanding of global market dynamics, including U.S. and ex-U.S. commercialization considerations
  • Experience building or scaling capabilities, functions, or operating models
  • Advanced analytical and strategic thinking skills, with the ability to translate complex data into actionable, enterprise-level decisions
  • Exceptional communication and executive presence
  • Experience in endocrinology is preferred
  • Strong vendor management, budget oversight, and project management skills
  • High degree of initiative, curiosity, and comfort with ambiguity in a fast-paced, mission-driven environment

Work Location and Conditions

** Preference will be given to candidates residing in the Boston area or elsewhere on the East Coast.

  • At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii Michigan and Tennessee.
  • You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested.
  • You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.

Compensation

The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.

Estimated Pay Range

$257,000 - $289,000 USD

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Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

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