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Vice President, Commercial Operations

Annexon HQ – Brisbane, CA or Remote (US)

Company: 

At Annexon Biosciences we are a biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye. Our novel scientific approach targets upstream C1q to block the classical complement inflammatory cascade before it starts, and its therapeutic candidates are designed to provide meaningful benefits across multiple autoimmune, neurodegenerative and ophthalmic diseases. With proof-of concept data in Guillain-Barré syndrome, Huntington’s disease and geographic atrophy, we are rigorously advancing our mid-to late-stage clinical trials to bring new potential treatments to patients as quickly as possible. At Annexon, you’ll be part of a team committed to making an impact together.   

 For more information on Annexon and our pipeline, check out our site Annexon Biosciences & Annexon Pipeline. We trade on Nasdaq under the ticker symbol ANNX and are headquartered in Brisbane, CA. 

 We seek applicants from all backgrounds to ensure we get the best, most creative talent on our team. We are building a diverse and inclusive workforce – come and be a part of our growth. 

 At Annexon, we are building a diverse, equitable, inclusive, and innovative company and we are looking for the BEST candidate for the job. That candidate may come from a less traditional background or may meet the qualifications in a different way. We would strongly encourage you to apply – especially if the reason you are the best candidate is not exactly as we describe it here. Learn more about Annexon’s commitment to diversity, equity, inclusion our values and culture! 

Position: 

The Vice President, Commercial Operations will lead all aspects of commercial operations to support the successful launch and commercialization of Annexon Biosciences' therapies. This role is responsible for developing and executing operational strategies that enable sales, marketing, and market access teams to maximize performance and deliver results. The VP will oversee sales operations, commercial analytics, incentive compensation, CRM systems, and other key functions to ensure operational excellence and data-driven decision-making across the commercial organization. 

Responsibilities include: 

  • Lead the design and implementation of commercial operations strategies to support the sales, marketing, and market access teams. 
  • Oversee the team responsible for MLR (Medical, Legal, Regulatory) review process, print and fulfillment operations, meeting and congress planning, and speaker bureau logistics to ensure smooth execution of all commercial initiatives.  
  • Oversee sales operations, including territory alignment, quota setting, incentive compensation, and performance tracking.  
  • Manage the development and optimization of CRM systems and other commercial tools, ensuring efficient use and seamless integration across teams.  
  • Drive commercial analytics and reporting to support data-driven decision-making, including sales forecasting, market analysis, and performance metrics.  
  • Partner with the marketing and sales leadership teams to design and manage market mix assessment and field force effectiveness initiatives.  
  • Lead pricing, contracting, and managed care operations to support access and reimbursement strategies.  
  • Develop and implement incentive compensation plans in conjunction with HR and that are aligned with corporate goals and sales performance.  
  • Collaborate with Finance, Legal, and Compliance teams to ensure adherence to internal policies and external regulations governing commercial operations.  
  • Optimize resource allocation across commercial functions, ensuring alignment with business priorities and return on investment.  
  • Serve as a key member of the commercial leadership team, contributing to long-term commercial strategy and planning. 

 Education, Experience, and Skills: 

Required: 

  • Bachelor's degree in Business, Finance, Marketing, or a related field. 15+ years of experience in commercial operations, sales operations, or a similar role within the pharmaceutical or biotechnology industry, with at least 7 years in a leadership position. 
  • Proven track record of successfully leading commercial operations in support of product launches and commercialization efforts.  
  • Strong understanding of sales operations processes, CRM systems, and commercial analytics.  
  • Experience developing and managing incentive compensation plans and sales force effectiveness programs.  
  • Ability to manage multiple projects and initiatives in a fast-paced, dynamic environment.  
  • Excellent leadership, communication, and collaboration skills, with a demonstrated ability to work cross-functionally.
  • Strong analytical and problem-solving skills, with a focus on data-driven decision-making.  

 Preferred:  

  • An MBA or advanced degree preferred.
  • Experience in rare diseases, specialty pharmaceuticals, or biologics.  
  • Familiarity with market access, pricing, and reimbursement strategies. 

Salary Range: $270,000 to $330,000 

Benefits: 

  • A stimulating and rewarding workplace includes flexible work schedules, remote opportunities and the ability to achieve a work-life balance.
  • We are located in Brisbane, CA, with shuttle service from BART, CalTrain and the Ferry.
  • Annexon offers a competitive base salary and equity participation, employee stock purchase plan, as well as a comprehensive health benefit package that includes medical, dental, vision, 401(k), flexible spending plans, as well as other benefits. 

Annexon Biosciences is an Equal Opportunity Employer, and we prohibit discrimination or harassment of any kind.  We are committed to fostering an environment where ALL people are welcome and supported. We cultivate a culture of inclusion for all employees that respects their individual strengths, views, and experiences. We believe that our differences enable us to be a better team – one that makes better decisions, drives innovation, and delivers better business results. Creativity and innovation flourish in an environment of openness, inclusion, and mutual respect. 

Staffing Agencies: Annexon Biosciences does not accept unsolicited agency resumes and will not pay fees to any third-party agency or firm that doesn’t have a signed agreement with Annexon Biosciences. Please do not send agency CVs/resumes through Annexon’s website or Annexon Employees.  Inquiries must be sent to talentacquisition@annexonbio.com with the Subject: Staffing Agency Request. 

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