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Executive Director, Health Economics Outcomes Researcher (HEOR)

San Francisco Bay Area or Remote (US)

Company: 

At Annexon Biosciences we are a biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye. Our novel scientific approach targets upstream C1q to block the classical complement inflammatory cascade before it starts, and its therapeutic candidates are designed to provide meaningful benefits across multiple autoimmune, neurodegenerative and ophthalmic diseases. With proof-of concept data in Guillain-Barré syndrome, Huntington’s disease and geographic atrophy, we are rigorously advancing our mid-to late-stage clinical trials to bring new potential treatments to patients as quickly as possible. At Annexon, you’ll be part of a team committed to making an impact together.   

For more information on Annexon and our pipeline, check out our site Annexon Biosciences & Annexon Pipeline. We trade on Nasdaq under the ticker symbol ANNX and are headquartered in Brisbane, CA. 

We're seeking exceptional talent from all backgrounds to fuel our growth. At Annexon, we're building a diverse, equitable, and inclusive workplace. We value unique perspectives and unconventional paths. If you're the best candidate for the job, even if you don't perfectly fit the traditional mold, we encourage you to apply. Learn more about our commitment to diversity, equity, inclusion, and our company culture! 

Position: 

The Executive Director of Health Economics Outcomes Researcher (HEOR) is responsible for leading the strategy and execution of HEOR programs to assess the clinical and economic impact of healthcare interventions in the real world, with the goal of helping healthcare organizations make informed decisions. As the leader of HEOR at Annexon, you will explore and develop novel approaches to high-impact, near-real time value evidence generation throughout product lifecycle of Annexon portfolio, and build on-going professional relationships with healthcare decision makers, public and private payers and policy makers, as well as HEOR researchers. This is an exceptional opportunity to contribute to the advancement of healthcare by providing evidence-based insights that can shape the future of patient care.    

Responsibilities include: 

  • Develop high-impact HEOR strategy and lead efficient and timely execution of programs supporting the value propositions of Annexon’s product portfolio.
  • Ensure HEOR evidence addresses the needs and expectations of key stakeholders such as patients, healthcare providers, payers and Health Technology Assessment (HTA) agencies.
  • Effectively present research findings to internal and external stakeholders to improve internal decision making and to promote wider adoption of research findings across external stakeholders.
  • Promote the value propositions of Annexon’s portfolio allowing key healthcare and formulary professionals to make informed therapeutic decisions.
  • Collaborate with internal stakeholders including medical affairs, marketing, and clinical teams to ensure that relevant health economics data are integrated into clinical studies and commercialization plans.
  • Input into clinical trial design to enable “augmented” clinical trials with post-trial linkages to real-world data, when appropriate, and lead HTA regulatory submissions.
  • Provide strategic guidance to internal teams on healthcare resource allocation, pricing and access strategies.
  • Engage and collaborate with external partners including payers, health care providers, thought leaders, and decision-makers to establish/ maintain strong partnerships and gather insights into research programs.
  • Explore novel industry-leading approaches to building real-world data platforms (as an alternative to or inclusive of traditional registries) that enable fast, efficient and near-real time Real World Evidence (RWE) generation.
  • Promote research efficiency through technology to standardize research processes and enable cumulative research intelligence capabilities.
  • Lead real-world research partnership engagements with leading healthcare, academic and payer organizations to co-create value evidence and help drive evidence-based optimal care.
  • Stay up to date with and add to the advancements in health economics methodologies and best practices.
  • Identify and interface with HEOR & RWE experts and organizations, profile data sources and related organizations as they relate to Annexon’s products and therapeutic areas.
  • Closely monitor new trends in health policy and payer environment, assess competitive data gaps and communicate to the organization, to help Annexon build industry-leading capabilities and be in the cutting edge of Evidence Based Medicine issues and HEOR data for purposes of strategic and commercial planning.
  • Embrace the company culture, “Warrior Spirit,” “Sound Judgment,” “Passion,” “All for One,” and “Thrive” and lead by example.
  • Lead or contribute to development of Medical and HEOR function through leadership of functional initiatives and change management.
  • Provide coaching and feedback, if necessary, to associates to help associates reach top performance  

Education, Experience, and Skills: 

  • Prior experience in health economics, outcomes research, patient-reported outcomes or related fields in the biotechnology or pharmaceutical industry.
  • Experience in rare diseases, neurology, ophthalmology, or immunology drug development is highly desirable.
  • Minimum 12 years of relevant experience with an advanced degree in a relevant field (PhD, DrPH, PharmD, MS).
  • Strong written and interpersonal communication skills, with an ability to present complex technical information clearly.
  • Knowledge and experience in managed care, integrated delivery networks, formulary decision-making, and payment/access models.
  • Ability to establish relationships with experts in real world evidence (RWE) and therapeutic areas of interest.  

Salary Range: $271,000 to $301,000 

Location: Annexon Biosciences is located in Brisbane, California and preference is given to candidates in the San Fransisco Bay Area. This position may be on-site or remote (within the US).

Benefits: 

  • A stimulating and rewarding workplace includes flexible work schedules, remote opportunities and the ability to achieve a work-life balance.
  • Shuttle service from BART, CalTrain and the Ferry.
  • Annexon offers a competitive base salary and equity participation, employee stock purchase plan, as well as a comprehensive health benefit package that includes medical, dental, vision, 401(k), flexible spending plans, and other benefits. 

Annexon Biosciences is an Equal Opportunity Employer, and we prohibit discrimination or harassment of any kind.  We are committed to fostering an environment where ALL people are welcome and supported. We cultivate a culture of inclusion for all employees that respects their individual strengths, views, and experiences. We believe that our differences enable us to be a better team – one that makes better decisions, drives innovation, and delivers better business results. Creativity and innovation flourish in an environment of openness, inclusion, and mutual respect. 

Staffing Agencies: Annexon Biosciences does not accept unsolicited agency resumes and will not pay fees to any third-party agency or firm that doesn’t have a signed agreement with Annexon Biosciences. Please do not send agency CVs/resumes through Annexon’s website or Annexon Employees.  Inquiries must be sent to talentacquisition@annexonbio.com.

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