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Associate Director, I&I Biology
Boston, MA
About Apogee Therapeutics
Founded in 2022, Apogee Therapeutics, Inc. (Ticker: APGE) is a well-funded, Nasdaq listed company that offers the opportunity to work in a fast-paced, highly dynamic environment. At Apogee, you can actively contribute to shaping the company culture, take on various roles and responsibilities, and grow professionally.
Apogee Therapeutics, Inc. is a biotechnology company seeking to develop differentiated biologics for the treatment of atopic dermatitis, chronic obstructive pulmonary disease and other inflammatory and immunology indications with high unmet need. Our antibody programs are designed to potentially overcome limitations of existing therapies by targeting well-established mechanisms of action and incorporating advanced antibody engineering to optimize half-life and other properties. We seek to reshape the current standard of care for inflammatory and immune diseases because we believe people living with these diseases deserve the best possible treatment, and we refuse to stop at “good enough.”
We are a fast-paced company committed to building an exceptional company culture, founded on our C.O.R.E. values: Caring, Original, Resilient and Egoless.
If this sounds like you, keep reading!
Role Summary
The Apogee Research and Translational Medicine team is seeking an Associate Director, I&I Biology. Reporting to the Executive Director of Non-Clinical Pharmacology this candidate will lead and mentor a team of scientists in the Non-Clinical Pharmacology group. This role will provide scientific leadership for studies defining antibody mechanisms of action (MOA), including new target evaluation and antibody discovery.
Key Responsibilities
- Leverage a strong background in biology/pharmacology to provide strategic vision and guide therapeutic antibody research in the context of atopic dermatitis, asthma, COPD, and other potential therapeutic opportunities.
- Oversee the implementation of epithelial cell culture techniques, cellular assays, and in vitro models to evaluate the activity of therapeutic antibody candidates.
- Support the authorship and review of documents supporting regulatory submissions, IP, and scientific publications.
- Manage and coordinate projects (in-house & CRO) to ensure adherence to timelines and goals.
- Aid in the development of lab best practice (operations, SOP generation, & documentation).
- Provide leadership in a managerial role, guiding and mentoring a team of scientists.
- Apply strong analytical skills to plan, execute, analyze and interpret data from experiments and studies related to antibody development.
- Collaborate with scientists across different groups and functional areas to generate high quality data to support programs in discovery through development
Ideal Candidate
- PhD and 6-8 years of scientific/technical experience in biotech/pharma.
- Subject matter expertise in Biologist/Pharmacology; experience with anti-inflammatory drug development in Atopic Dermatitis, COPD, and/or Asthma indications is desirable.
- Broad expertise developing complex in vitro, ex vivo, and in vivo assays to characterize & develop therapeutic antibodies.
- Experience managing a developing team of scientists and operating a budget.
- Ability to coordinate multiple projects with tight timelines and shifting priorities.
- CRO management experience including evaluation of new CROs a plus.
- Successfully exhibit Apogee’s C.O.R.E. values: Caring, Original, Resilient and Egoless.
- Able and willing to travel approximately 10% for team and company meetings.
- Position is based on-site in our lab and office space in the Boston Seaport area.
What We Offer
- A great culture, grounded in our C.O.R.E. values: Caring, Original, Resilient and Egoless
- Opportunity to work in a fast-paced, highly dynamic environment where you help shape the culture and company, wear multiple hats, and learn quickly
- Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits
- Flexible PTO
- Two, one-week company-wide shutdowns each year
- Commitment to growing you professionally and providing access to resources to further your development
- Apogee offers regular all team, in-person meetings to build relationships and problem solve
E-Verify Participation: As part of the I9 verification of authorization to work in the US, Apogee participates in E-Verify. To learn more about E-Verify please review this poster.
Apogee Therapeutics is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.
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