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Associate Director, Biomarker Discovery and Development

Boston

 

About Apogee Therapeutics
Founded in 2022, Apogee Therapeutics, Inc. (Ticker: APGE) is a well-funded, Nasdaq listed company that offers the opportunity to work in a fast-paced, highly dynamic environment. At Apogee, you can actively contribute to shaping the company culture, take on various roles and responsibilities, and grow professionally.
Apogee Therapeutics, Inc. is a biotechnology company seeking to develop differentiated biologics for the treatment of atopic dermatitis, chronic obstructive pulmonary disease and other inflammatory and immunology indications with high unmet need. Our antibody programs are designed to potentially overcome limitations of existing therapies by targeting well-established mechanisms of action and incorporating advanced antibody engineering to optimize half-life and other properties. We seek to reshape the current standard of care for inflammatory and immune diseases because we believe people living with these diseases deserve the best possible treatment, and we refuse to stop at “good enough.”
We are a fast-paced company committed to building an exceptional company culture, founded on our C.O.R.E. values: Caring, Original, Resilient and Egoless. 
If this sounds like you, keep reading!

 

Role Summary

The Research and Translational Medicine department is seeking an Associate Director, Biomarker Discovery and Development. In this newly created role will be responsible for biomarker strategy and execution and analysis of biomarker data generated across Apogee clinical studies. You will also head the preclinical and clinical biomarker assay group at Smart Labs located in the Seaport in Boston.

Key Responsibilities

  • Work across functions in Translational Research and Clinical to develop and execute biomarker strategies for clinical programs.
  • Process and analyze biomarker datasets including genomics, proteomics, and transcriptomics data from discovery projects through clinical studies. Perform statistical and computational analysis to identify correlations and insights. Integrate multi-omics data to support biomarker discovery and validation efforts.
  • Manage the day-to-day operations of the preclinical and clinical biomarker assay group including resourcing and oversight of assay selection, feasibility, troubleshooting, qualification, and clinical sample testing.
  • Establish and maintain excellent relations with CROs to execute biomarker strategies, monitor assay development including timely qualification/validation and sample testing in clinical trials to ensure high quality data generation. Lead the implementation of assays using flow cytometry, immunoassays, proteomics, and genomics-based tools for clinical trials.
  • Work closely with cross-functional teams on patent and publication readiness, SOP finalization, clinical protocols, lab manuals

Ideal Candidate 

  • PhD with a minimum of 8 years of pharmaceutical/biotech industry experience.
  • Experience in I&I indications of Dermatology and Respiratory.
  • Experience managing team of biomarker scientists.
  • Proficiency in statistical programing languages such as R and bioinformatics tools.
  • Strong understanding of biological and multimodal data types.
  • Enjoys fast paced environment, flexible, able to manage multiple and competing priorities under tight timelines.
  • Extensive experience in clinical biomarker strategy and execution, deep understanding of drug development stages and role for biomarkers.
  • Highly experienced in leading and collaborating effectively as a member of cross-functional teams, excellent communication skills to drive projects and manage timelines and present to a variety of stakeholders and tailor message accordingly.
  • Successfully exhibit Apogee’s C.O.R.E. values: Caring, Original, Resilient and Egoless
  • Position requires travel for regular team meetings including All Hands meetings and other workshops.
  • Candidates must be willing to work onsite at our lab in Boston a minimum of 3 days per week.

The anticipated salary range for candidates for this role will be $185,000-$200,000/year. The final salary offered will depend on several factors, which may include, but is not limited to relevant years of experience, educational background, and geography.

 

What We Offer
  • A great culture, grounded in our C.O.R.E. values: Caring, Original, Resilient and Egoless
  • Opportunity to work in a fast-paced, highly dynamic environment where you help shape the culture and company, wear multiple hats, and learn quickly
  • Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits
  • Flexible PTO
  • Two, one-week company-wide shutdowns each year
  • Commitment to growing you professionally and providing access to resources to further your development
  • Apogee offers regular all team, in-person meetings to build relationships and problem solve
 
E-Verify Participation: As part of the I9 verification of authorization to work in the US, Apogee participates in E-Verify. To learn more about E-Verify please review this poster.
 
Apogee Therapeutics is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.
 
To review our privacy policy, click here

 

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