Discovery Intern

Who We Are 

Arcellx is a public, clinical-stage biotechnology company reimagining cell therapy by engineering innovative immunotherapies for patients with cancer and other incurable diseases. We believe that cell therapies are one of the forward pillars of medicine and our mission is to destroy cancer and advance humanity by developing cell therapies that are safer, more effective, and more broadly accessible.  

Our team members are made up of talented innovators and dreamers working from our offices in Rockville, Maryland, and Redwood City, California. At Arcellx, we hire exceptional people and create a fun, diverse, supportive, and informal environment that allows everyone to do their best work.  

What Matters to Us 

Living our core values is essential to maintaining a work environment that is high-performing, inclusive, and collaborative. We look for candidates who demonstrate strong values alignment and bring different backgrounds, viewpoints, and abilities to the team. 

Arcellx Core Values 

• Character: Committed to always doing what’s right.  

• Audacity: Willing to challenge convention and share candid feedback with others.  

• Determination: Curious and self-motivated. Always looking to improve and learn.    

• Collaboration: "No job is too small" mentality. Humble and willing to help others.  

• Originality: Will bring your unique perspective to the table and respect a diverse set of views and backgrounds.  

The “Fine Print” – What You’ll Do  

As an intern, you will take ownership of a key project focused on phage display technology to improve selection strategies, library design, and screening methodologies: 

• Phage display – Optimize our current phage display platform for the selection of low affinity binders. 

• Cloning and gene sequencing – Construct and validate libraries, perform PCR, sequence DNA, and analyze data. 

• Contributing to data analysis and troubleshooting – Interpret sequencing and binding assay results, troubleshoot experimental challenges, and propose optimization strategies. 

Skills and Experience We Look For  

• Undergraduate or Master’s degree-level coursework covering the concepts behind immunotherapy, and cell therapy.  

• Familiarity with molecular biology methods, including primer design, PCR, gel electrophoresis, plasmid DNA preparation, cloning, and sequence analysis using SnapGene or similar software.  

• Preferred knowledge of additional methods including DNA extraction and real-time PCR analysis, flow cytometry, and bioinformatics. 

Our ideal candidate would have an enthusiasm for scientific discovery, interest in biotechnology, knowledge of the field, familiarity with molecular biology and cell culture techniques, be well-organized, work well with a team, and have the initiative to individually drive a project forward.   

Join us in our quest to reimagine cell therapy and destroy cancer. For more on our technology, culture, and team, go to www.arcellx.com.

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