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Research Associate II, Gilbert Lab

Palo Alto, CA

About Arc Institute

The Arc Institute is a new scientific institution that conducts curiosity-driven basic science and technology development to understand and treat complex human diseases. Headquartered in Palo Alto, California, Arc is an independent research organization founded on the belief that many important research programs will be enabled by new institutional models. Arc operates in partnership with Stanford University, UCSF, and UC Berkeley.

 

While the prevailing university research model has yielded many tremendous successes, we believe in the importance of institutional experimentation as a way to make progress. These include:

 

  • Funding: Arc will fully fund Core Investigators’ (PIs’) research groups, liberating scientists from the typical constraints of project-based external grants.
  • Technology: Biomedical research has become increasingly dependent on complex tooling. Arc Technology Centers develop, optimize and deploy rapidly advancing experimental and computational technologies in collaboration with Core Investigators. 
  • Support: Arc aims to provide first-class support—operationally, financially and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction.
  • Culture: We believe that culture matters enormously in science and that excellence is difficult to sustain. We aim to create a culture that is focused on scientific curiosity, a deep commitment to truth, broad ambition, and selfless collaboration.

 

Arc has scaled to nearly 200 people. With $650M+ in committed funding and a state of the art new lab facility in Palo Alto, Arc will continue to grow quickly in the coming years.

 

About the position

We are looking for a highly motivated, well-organized, and technically proficient Research Associate II to join the Gilbert laboratory at the Arc Institute. In this position, you will contribute to the development of new technologies for functional genomics and gain expertise in molecular biology, mammalian cell culture, and cell engineering. You will have the opportunity to work with scientists in single-cell genomics, computational biology, and CRISPR-Cas systems. The Research Associate will be expected to work independently and collaboratively with members of the Gilbert laboratory. A successful applicant will demonstrate attention to detail, an eagerness to learn new skills, and the ability to self-direct. Compensation will be competitive with industry jobs relative to experience level and background.

 

About you

  • You are excited about a broad range of scientific and research topics and have taken a variety of courses to explore your interests.
  • You are organized and detail-oriented when planning and performing experimental tasks. 
  • You think about scientific questions critically, pursuing a deep understanding of each experimental step. 
  • You thrive in a team environment, working collaboratively at a fast pace.
  • You enjoy exploring new technologies and how they enable large-scale multi-omic biological measurements.
  • You explicitly wish to use this experience to gain entry into a PhD program and are able to provide a minimum 2-year commitment to build a portfolio of work to support you in that endeavor.

 

In this position you will

  • Utilize a wide array of molecular biology techniques, such as restriction enzyme cloning, Gibson Assembly, Golden Gate Assembly, gel electrophoresis, cDNA synthesis, PCR, qPCR, bacterial transformation, DNA & RNA purification, ELISA, and NGS sample preparation
  • Gain experience in mammalian cell culture, flow cytometry, AAV & lentivirus production, cell engineering, and computational biology
  • Assist with research planning, execution, analysis, troubleshooting, and data interpretation with support from the Gilbert laboratory
  • Develop into a well-rounded researcher through reading applicable literature, taking ownership of experiments, and collaborating with Arc Scientists
  • Maintain careful records, work independently, and communicate experimental results clearly
  • Thrive in a fast-paced team environment 
  • Actively participate in journal club, lab meetings, and seminars through presentations and discussions

 

Requirements

  • BS/MS or equivalent professional experience in cell & molecular biology, biochemistry, bioengineering, or similar field. 
  • 2+ years of relevant experience in an academic or industry setting (including independent lab work during your undergraduate studies).
  • Hands-on experience with molecular biology techniques including qRT-PCR, PCR, DNA and RNA isolation, and DNA & RNA purification
  • Familiarity with scientific software (Prism/FloJo) or programming languages (Python/R) for data analysis. 
  • Display broad interest in scientific research, demonstrated through courses or research projects
  • Must have excellent written and oral communication skills.
  • Must have strong attention to detail and organization skills, as well as the ability to troubleshoot experiments independently. 
  • Highly collaborative, team-oriented, Self-motivated and take ownership of projects.

 

The base salary for this position is $73,700. This amount does not include benefits or other forms of compensation.

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