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Senior Manager, Financial Planning & Analysis

Chesterbrook, PA

At Avalo (ahh-vah'-low), we are 100% focused on developing treatments for immune-mediated inflammatory diseases with large unmet needs that affect millions worldwide. Our strategy is to develop medicines that target the IL-1β pathway, which is a central driver of the inflammatory process.

We share a commitment to teamwork, passion for science, and dedication to patients suffering from acute and chronic inflammatory disorders. Our collective expertise in discovery, development, and regulatory approvals is evidenced in our strong individual track records of advancing multiple therapeutic programs to successful commercialization.

Position Summary:

The Senior Manager, Financial Planning & Analysis (FP&A) serves as a strategic finance partner to Research & Development (R&D), including clinical operations, non-clinical, CMC, and other key business functions. This role is responsible for financial planning, forecasting, performance analysis, and decision support, helping ensure that business objectives are aligned with financial stewardship and operational execution. The ideal candidate combines strong financial expertise with an understanding of the drug development and thrives in a collaborative, fast-paced environment.

Essential Duties and Responsibilities:

  • Partner with R&D, non-clinical, clinical operations, CMC, and cross-functional stakeholders to develop annual budgets, forecasts, long-range plans, and financial projections, as integral part of development team.
  • Drive company-wide planning processes, including the annual budgeting process and quarterly forecasts.
  • Act as a finance partner to R&D and G&A teams to align financial plans with operational execution.
  • Operate as a key member of a small finance team, supporting a broad range of activities beyond core FP&A.
  • Monitor and forecast cash burn and liquidity, providing visibility into runway under multiple scenarios.
  • Prepare and deliver financial analyses, management reporting, board materials, and variance analyses that support executive decision-making. 
  • Serve as a trusted finance business partner, providing actionable insights, recommendations, and scenario modeling to support strategic and operational initiatives. 
  • Develop and maintain financial models, business cases, investment analyses, and resource planning tools to evaluate opportunities and risks. 
  • Improve and scale forecasting processes and financial systems.
  • Support month-end close activities in partnership with accounting, including accruals, spending analyses, and budget-to-actual reporting.
  • Monitor and manage departmental expenses, including vendor commitments, contracts, and invoices to ensure appropriate financial controls. 
  • Partner with business leaders to identify financial drivers, assess performance trends, and recommend corrective actions, driving accountability for budget adherence while enabling strategic flexibility.
  • Support corporate initiatives through financial analysis, planning alignment, and reporting support. 
  • Drive continuous improvement of FP&A processes, reporting capabilities, financial systems, and planning tools to enhance efficiency, accuracy, and scalability. 
  • Other duties as assigned.

Required Education and Experience:

  • Bachelor's degree in finance, accounting, economics, or related field required; MBA, MS Finance, CPA, CMA, or CFA preferred.
  • 8+ years of progressive FP&A experience, including budgeting, forecasting, financial modeling, and executive-level financial reporting.
  • Experience supporting R&D, clinical development, or life sciences organizations preferred.
  • Strong knowledge of financial statements, including P&L, balance sheet, and cash flow analysis.
  • Advanced financial modeling and analytical skills with the ability to translate complex data into actionable business insights.
  • Experience leading annual budget process, forecasting cycles, and cross-functional financial reviews.
  • Strong business partnering skills with the ability to influence stakeholders and communicate effectively across all levels of the organization.
  • Experience with financial planning systems and ERP platforms required, with implementation experience preferred
  • Demonstrated ability to improve processes, implement scalable solutions, and enhance reporting capabilities.

Additional Skills, Knowledge, and/or Responsibilities:

  • Biotech/Pharmaceutical industry experience preferred

About Avalo Therapeutics

Avalo Therapeutics is a clinical stage biotechnology company fully dedicated to developing IL-1β-based treatments for immune-mediated inflammatory diseases. Our lead asset, AVTX-009, is in a Phase 2 clinical trial for hidradenitis suppurativa (HS). We’re also exploring additional opportunities to make an impact in prevalent indications that have significant remaining unmet needs. For more information about Avalo, please visit www.avalotx.com.

ATTENTION: External Agencies and Placement Firms

A member of the Avalo Human Resources Department will contact an agency directly if an open position is eligible to be sourced from an outside recruiting service. Avalo does not accept unsolicited resumes from employment agencies for any employment opportunity. All agencies/recruiters must have a written agreement/SOW in place with Avalo and prior to submitting any resume or CV.

All resumes must be submitted through the appropriate process. Any resumes submitted without an agreement and/or any resumes sent unsolicited through e-mail accounts of Avalo employees will be considered outside of the appropriate process, do not imply or create any obligation on our part, do not impart any restrictions on Avalo with respect to the hiring of any persons whose resumes are so submitted and are not eligible for placement fees.

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