Medical Director/ Senior Medical Director

About BridgeBio Oncology Therapeutics

BridgeBio Oncology Therapeutics (BBOT) is a clinical-stage biopharmaceutical company advancing a next generation pipeline of novel small molecule therapeutics targeting RAS and PI3K malignancies. Initially formed as a subsidiary of BridgeBio Services, BBOT completed a $200M private financing with external investors in 2024 with the goal of improving outcomes for patients with cancers driven by the two most prevalent oncogenes in human tumors. 

For more information visit bridgebiooncology.com.

Who You Are

Medical Director with proven track record of scientific and/or clinical accomplishments in either an academic or industry setting. Reporting to the Chief Medical and Development Officer, this role will have primary responsibility for all medical aspects pertaining to assigned clinical studies in treating multiple solid tumors. Candidates with experience in lung cancer is preferred. Responsibilities include executing global Phase 1 to Phase 3 studies. This role works collaboratively with multi-disciplinary teams responsible for designing, implementing, monitoring, analyzing, and reporting studies conducted within the BridegeBio Oncology Therapeutics portfolio to ensure the program meets the needs of patients and the business. This role will influence both internal and external audiences in a high-impact, prominent role as it actively contributes to the dynamic and innovative culture within the company.

Responsibilities

• Serve as clinical lead of a phase 1a/1b study and future late-stage studies, including contributing to/overseeing study start-up, enrollment, study medical monitoring, data cleaning, and CSR writing ·

• Partner with investigators and CROs to design and implement clinical studies, respectively ·

• Write protocols, investigator brochures, and clinical study reports, and review clinical trial documents ·

• Conduct investigator meetings and safety review committee meetings and lead site initiation visits with clinical trial investigators ·

• Execute and deploy drug development strategic plans, develop contingency plans, provide technical and strategic advice, and meet milestones and budgets ·

• Translate findings from research and non-clinical studies into clinical development opportunities ·

• Interact with clinical investigators and thought leaders ·

• Conduct clinical trials using ethical guidelines relevant to the pharmaceutical industry, and ensure compliance with these external guidelines

Education, Experience & Skills Requirements

· Scientific and patient-focused MD (or equivalent) or MD/PhD, or PhD, or prior clinical scientist experience with a deep commitment to understanding needs and improving the lives of patients, and a passion for developing   novel therapeutics ·

· Demonstrated ability to collaborate successfully with multiple functions in a team environment ·

· Demonstrated record of accomplishment in a compressed time frame; capable of prioritizing tasks and delivering on deadlines with high-performance standards and attention to detail ·

· Motivated to work in a fast-paced, high accountability, small company environment; a "can do" and collegial professional who leads through influence and interpersonal skills ·

· Intellectually curious with the courage to challenge and seek new ways to improve work ·

· Strong written and oral communication skills, including presentation skills · Ability to analyze and interpret data and develop written reports and presentations of those data ·

· Solid critical, strategic, and analytical thinking skills ·

· Experience in all aspects of protocol conduct, both early and late phases, including protocol writing, start-up, study execution, analysis, and reporting ·

· Travel (US and ex-US) required to scientific conferences and study sites as needed. ·