Back to jobs
New

Director, Clinical Supply Chain Operations & Global Logistics

Boston, Massachusetts, United States; Durham, North Carolina, United States

About Beeline Medicines:

Beeline Medicines is a clinical‑stage biotechnology company focused on developing and delivering category-leading precision therapies to transform the lives of people living with autoimmune and inflammatory diseases. With a portfolio of potential best-in-class and first-in-disease therapeutic candidates that directly target key pathways governing dysregulated immunological and inflammatory responses, the Company is developing medicines that have the opportunity to provide durable, life-changing impact. Led by an established executive team and backed by world-class life science investors, each day Beeline Medicines is determined to bring the scientific rigor and operational excellence to get to what matters for patients – realizing a world where people with immune-mediated diseases can live life fully.

Job Summary:

The Director, Clinical Supply Chain Operations & Global Logistics is a senior operational leader responsible for the end-to-end planning, execution, and oversight of clinical supply chain activities supporting the company's global clinical development programs. Reporting directly to the Chief Technical Operations Officer, this individual ensures that investigational medicinal products (IMPs) — spanning small molecules and biologics — are packaged, labeled, distributed, and tracked in compliance with global GMP, GDP, and regulatory requirements, and that clinical sites around the world receive the right product, in the right condition, at the right time. This role is the primary interface between CMC manufacturing, Clinical Operations,, Quality, and external and logistics partners, serving as the operational architect of a global clinical supply network that is reliable, scalable, and inspection ready. In a pre-commercial biotech environment, this leader must balance strategic supply chain design with hands-on execution, building infrastructure and processes that will scale from early-phase trials through global registrational studies.  In addition to clinical supply management, this role is also responsible for shipping, logistics and trade compliance for all material shipments (intermediates, drug substance, drug product and analytical materials) to support the global manufacturing supply chain.


Work Arrangement & Location: 

Hybrid - This position follows a hybrid work schedule, requiring a minimum of two (2) days on-site per week — currently designated as Tuesday and Wednesday. Additional on-site days may be required based on business needs, team priorities, or leadership direction.


Essential Duties and Responsibilities:

  • Design and lead the end-to-end clinical supply chain strategy for all active and planned clinical programs, encompassing demand forecasting, inventory planning, clinical packaging and labeling, IRT/IVRS configuration, distribution, and returns/destruction.
  • Own the global IMP distribution network, including selection and governance of third-party logistics (3PL) providers, cold chain carriers, and depot partners across North America, Europe, and global regions; ensure temperature-controlled supply chain integrity from CDMO release through site delivery.
  • Serve as the primary supply chain interface to Clinical Operations, ensuring clinical supply timelines are fully integrated into study startup plans, protocol amendments, site activation milestones, and enrollment projections.
  • Lead clinical supply planning and demand forecasting across multiple concurrent trials, using IRT/IVRS data and enrollment modeling to optimize inventory levels, minimize waste, and prevent supply disruptions to clinical sites.
  • Oversee clinical packaging, labeling, and secondary manufacturing activities at CDMO/CMO sites, ensuring compliance with country-specific labeling requirements, GMP expectations, and blinding requirements for randomized controlled trials.
  • Manage import/export logistics and global trade compliance for IMP shipments across all active clinical geographies, including coordination of regulatory import permits, customs documentation, and country-specific distribution authorizations.
  • Establish and govern relationships with CDMOs, 3PLs, comparator drug suppliers, and specialty logistics vendors; define performance expectations, conduct business reviews, and manage escalations to ensure supply reliability.
  • Partner with Quality Assurance to ensure clinical supply chain operations meet GDP/GMP requirements; lead or support regulatory agency inspections, internal audits, and CDMO quality reviews as they relate to clinical supply.
  • Build and maintain clinical supply chain SOPs, batch disposition records, chain-of-custody documentation, and reconciliation processes in alignment with ICH E6 (GCP), GMP, and GDP expectations; author and update pharmacy manuals, Investigator Brochure supply sections, and site handling guidance to ensure clinical site readiness across all active studies.
  • Lead investigation of supply chain exceptions and deviations, including root cause analysis, CAPA development, implementation, and closure; ensure all supply-related non-conformances are resolved in a timely, GMP-compliant manner and escalated appropriately.
  • Perform other duties and responsibilities as assigned


Qualifications:

  • Education: Bachelor's degree required in Supply Chain Management, Life Sciences, Engineering, Pharmacy, or a related discipline; advanced degree (M.S., MBA, or equivalent) strongly preferred.
  • 10+ years of clinical supply chain experience in the pharmaceutical or biopharmaceutical industry, with at least 3 years in a leadership role with direct accountability for global clinical supply operations.
  • Demonstrated expertise in end-to-end clinical supply chain management, including demand planning, IMP packaging and labeling, IRT/IVRS systems, global distribution, cold chain logistics, and depot management.
  • Deep knowledge of global GMP, GDP, and GCP regulations as they apply to clinical supply chain operations, including FDA 21 CFR Parts 211/312, EU GMP Annex 13, and ICH E6(R2); familiarity with country-specific import/export requirements across clinical geographies.
  • Familiarity with clinical supply chain management for both small molecules and biologics/large molecules, including specific cold chain and stability considerations for protein-based therapeutics.
  • Proficiency with supply chain management tools, ERP/CTMS systems, and clinical supply planning platforms;
  • Track record of building clinical supply chain infrastructure, SOPs, and operational processes in a pre-commercial or rapidly scaling biotech organization.
  • Demonstrated ability to lead through influence in a matrixed organization, aligning Clinical Operations, CMC, Quality, Regulatory, and Finance stakeholders around supply chain priorities without direct authority over all constituents.
  • Proven track record of operating effectively in pre-commercial, resource-constrained environments — building clinical supply infrastructure from the ground up while simultaneously executing against active trial timelines.
  • Experience as a trusted operational and strategic partner to senior leaders, with the credibility and judgment to escalate supply risks, recommend course corrections, and drive rapid resolution.
  • Strong written communication skills, with experience producing high-quality supply chain status reports, risk registers, executive summaries, and regulatory-facing supply documentation.
  • Skilled facilitator with experience leading cross-functional supply chain review meetings, risk escalation discussions, and vendor business reviews with clarity, structure, and decisive follow-through.
  • Collaborative communication style with the ability to build credibility and trust quickly across scientific, clinical, operational, financial, and external partner stakeholders in a fast-moving, global biotech environment

Salary Range:

The expected annual salary range for this position is listed below. Actual pay will be determined based on experience, qualifications, location, and other job-related factors permitted by law. A discretionary annual bonus and long-term incentive award (e.g., equity) may be available based on individual and Company performance.

Salary Range

$214,849 - $227,040 USD

Benefits:

We offer a comprehensive benefits package including:

  • Medical, Dental & Vision insurance (employee premiums 100% covered by company)
  • 20 accrued days combined time off (PTO/Sick), 12 company holidays, & winter recharge
  • Flexible work arrangements / hybrid schedule
  • Health Savings Account (HSA)

*Benefits are subject to eligibility requirements and plan terms. Additional details provided during the offer process*

Equal Employment Opportunity:

Beeline Medicines is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, national origin, disability, age, protected veteran status, or any other characteristic protected by applicable federal, state, or local law.

Reasonable Accommodation:

If you require a reasonable accommodation to participate in the application or interview process, please contact careers@beelinemedicines.com to request an accommodation. We are committed to providing equal access to all candidates.

Privacy

Upon submission of this form I understand that Beeline Medicines is based in the United States and personal data submitted in the form will be transferred and accessed in the U.S., Information about Beeline Medicines privacy practices can be found at Privacy Policy - Beeline Medicines

Apply for this job

*

indicates a required field

Resume/CV*

Accepted file types: pdf, doc, docx, txt, rtf

Select...
Select...
Select...
Select...

When you apply to a job on this site, the personal data contained in your application will be collected by Beeline Medicines Corporation (“Controller”), which is located at 200 Clarendon Street, Boston, MA 02116, United States and can be contacted by emailing Privacy@beelinemedicines.com. Controller’s data protection officer is James Finchen, who can be contacted at Privacy@beelinemedicines.com. Your personal data will be processed for the purposes of managing Controller’s recruitment related activities, which include setting up and conducting interviews and tests for applicants, evaluating and assessing the results thereto, and as is otherwise needed in the recruitment and hiring processes. Such processing is legally permissible under Art. 6(1)(f) of Regulation (EU) 2016/679 (General Data Protection Regulation) as necessary for the purposes of the legitimate interests pursued by the Controller, which are the solicitation, evaluation, and selection of applicants for employment.

Your personal data will be shared with Greenhouse Software, Inc., a cloud services provider located in the United States of America and engaged by Controller to help manage its recruitment and hiring process on Controller’s behalf. Accordingly, if you are located outside of the United States, your personal data will be transferred to the United States once you submit it through this site. Greenhouse is certified to the EU-U.S. Data Privacy Framework, which the European Commission has determined ensures an adequate level of protection – comparable to that of the EU – for personal data transferred from the EU.

Your personal data will be retained by Controller as long as Controller determines it is necessary to evaluate your application for employment. Under the GDPR, you have the right to request access to your personal data, to request that your personal data be rectified or erased, and to request that processing of your personal data be restricted. You also have to right to data portability. In addition, you may lodge a complaint with an EU supervisory authority.

Select...

By acknowledging, I certify that the information I have provided in this application, resume, and any other materials submitted during the application process is true, complete, and accurate to the best of my knowledge. I understand that any false, misleading, incomplete, or omitted information may result in disqualification from further consideration for employment or, if discovered after hire, disciplinary action up to and including termination of employment.

I authorize the Company to contact my former employers, educational institutions, references, and other sources to the extent permitted by applicable law for purposes of verifying the accuracy of the information provided in this application (and/or in my resume) and gathering information regarding my work performance, academic performance/credentials and qualifications for the position(s) for which I am applying.

I understand that submission of this application does not guarantee employment and does not create an employment contract. If hired, I understand that my employment will be at will, meaning that either I or the Company may terminate the employment relationship at any time, with or without notice and with or without cause, subject to applicable law.

U.S. Standard Demographic Questions

We invite applicants to share their demographic background. If you choose to complete this survey, your responses may be used to identify areas of improvement in our hiring process.
Select...
Select...
Select...
Select...
Select...
Select...

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in Beeline Medicines’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

Select...
Select...
Race & Ethnicity Definitions

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Select...

Voluntary Self-Identification of Disability

Form CC-305
Page 1 of 1
OMB Control Number 1250-0005
Expires 04/30/2026

Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

  • Alcohol or other substance use disorder (not currently using drugs illegally)
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
  • Blind or low vision
  • Cancer (past or present)
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or serious difficulty hearing
  • Diabetes
  • Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
  • Epilepsy or other seizure disorder
  • Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
  • Intellectual or developmental disability
  • Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
  • Missing limbs or partially missing limbs
  • Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
  • Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
  • Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
  • Partial or complete paralysis (any cause)
  • Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
  • Short stature (dwarfism)
  • Traumatic brain injury
Select...

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.