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Associate Director, R&D Program Management

Boston, Massachusetts, United States

About Beeline Medicines:

Beeline Medicines is a clinical‑stage biotechnology company focused on developing and delivering category-leading precision therapies to transform the lives of people living with autoimmune and inflammatory diseases. With a portfolio of potential best-in-class and first-in-disease therapeutic candidates that directly target key pathways governing dysregulated immunological and inflammatory responses, the Company is developing medicines that have the opportunity to provide durable, life-changing impact. Led by an established executive team and backed by world-class life science investors, each day Beeline Medicines is determined to bring the scientific rigor and operational excellence to get to what matters for patients – realizing a world where people with immune-mediated diseases can live life fully.

Job Summary:

The Associate Director, Program Management is a core member of the R&D Program Management team and supports cross-functional planning, coordination, and execution of multiple early- to mid-stage drug development programs within the Company's portfolio. The Associate Director works closely with one or more Program Leaders, providing reliable operational support and contributing to the overall discipline and effectiveness of the program team. In addition, this individual will support Portfolio-level governance processes.

The Associate Director will be a trusted partner across R&D, CMC/Technical Operations, Medical Affairs, Alliance Management, and G&A functions, helping to maintain alignment between program priorities, timelines, and day-to-day activities. This individual will prepare program materials, coordinate cross-functional working group activities, and support strategic planning efforts as directed.

The ideal candidate is detail-oriented, proactive, and comfortable operating in a fast-paced environment. They bring strong organizational skills, sound judgment on when to escalate, and a collaborative approach that keeps program teams informed, aligned, and moving forward on clinical-stage development programs within Immunology & Inflammation (I&I).


Work Arrangement & Location: 

Hybrid - This position follows a hybrid work schedule, requiring a minimum of two (2) days on-site per week — currently designated as Tuesday and Wednesday. Additional on-site days may be required based on business needs, team priorities, or leadership direction.


Essential Duties and Responsibilities:

  • Support program leadership in the development and maintenance of integrated development plans, including development strategies, timelines, scenario plans, budgets, resource planning, goal setting, and risk assessment and monitoring.
  • Coordinate cross-functional team meetings — developing agendas, tracking action items and decisions through meeting minutes, and followi-ups with workstream owners — to maintain discipline and momentum in program execution.
  • Support the preparation of program updates, dashboards, and governance deliverables, ensuring materials are accurate, well-organized, and ready for review at key governance meetings and leadership touchpoints.
  • Coordinate and support selected cross-functional working groups, helping organize logistics, track outputs, and ensure workgroup activities stay aligned with program timelines and priorities.
  • Support the integrity of project plans by maintaining accurate documentation and flagging inconsistencies or risks to program leadership in a timely manner.
  • Maintain accurate and current program documentation, including risk logs, decision trackers, key assumptions, and milestone summaries for internal activities and alliance management; contribute to the development and upkeep of the risk management plan under direction of program leadership.
  • Provide operational support for R&D Governance activities, including agenda planning and meeting management.
  • Foster a collaborative, solutions-oriented environment that supports effective teamwork across cross-functional stakeholders.
  • Perform other duties and responsibilities as assigned


Qualifications:

  • Education: Bachelor's degree required in life sciences, engineering, or a related field; advanced degree (MS, MBA, or PhD) preferred.
  • Minimum of 7 years of experience in program or project management within the biopharmaceutical or biotechnology industry, with meaningful exposure to clinical-stage drug development programs preferred.
  • Working knowledge of drug development processes, including IND-enabling studies and Phase 1–3 clinical execution; familiarity with marketing submission milestones (NDA/BLA) is a plus.
  • Experience supporting program governance processes, including the preparation of meeting materials and program status updates for internal leadership audiences.
  • Proficient in building and maintaining detailed project plans in Smartsheets, tracking progress, integrating project plans across the enterprise, and proven ability to communicate status to program teams and leadership.
  • Demonstrated ability to coordinate cross-functional teams and maintain accountability in a matrix organization, with experience influencing peers and functional contributors without direct authority.
  • Solid scientific literacy in drug development; familiarity with immunology, inflammation, or rare disease therapeutic areas is an advantage.
  • Strong organizational skills with attention to detail and the ability to manage multiple concurrent workstreams accurately and on time.
  • Supports program execution by helping teams stay organized, accountable, and on track — proactively identifying gaps and bringing solutions rather than problems to program leadership.
  • Communicates program status, risks, and key updates clearly and consistently across cross-functional teams, ensuring workstream owners and program leadership stay aligned and informed.
  • Maintains a proactive communication rhythm within the program team, helping ensure that information flows efficiently across functions and that misalignments are surfaced and addressed quickly.

Salary Range:

The expected annual salary range for this position is listed below. Actual pay will be determined based on experience, qualifications, location, and other job-related factors permitted by law. A discretionary annual bonus and long-term incentive award (e.g., equity) may be available based on individual and Company performance.

Salary Range

$190,000 - $215,000 USD

Benefits:

We offer a comprehensive benefits package including:

  • Medical, Dental & Vision insurance (employee premiums 100% covered by company)
  • 20 accrued days combined time off (PTO/Sick), 12 company holidays, & winter recharge
  • Flexible work arrangements / hybrid schedule
  • Health Savings Account (HSA)

*Benefits are subject to eligibility requirements and plan terms. Additional details provided during the offer process*

Equal Employment Opportunity:

Beeline Medicines is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, national origin, disability, age, protected veteran status, or any other characteristic protected by applicable federal, state, or local law.

Reasonable Accommodation:

If you require a reasonable accommodation to participate in the application or interview process, please contact careers@beelinemedicines.com to request an accommodation. We are committed to providing equal access to all candidates.

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