Pre-Analytical Supervisor

BillionToOne is a next-generation molecular diagnostics company dedicated to developing powerful and accurate diagnostic tests that are accessible to all. Our innovative QCT molecular counting technology significantly enhances the resolution of disease detection using cell-free DNA by over a thousandfold. This groundbreaking technology is integral to our product offerings, including one of our flagship products, Unity Complete™, the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Leveraging the same molecular counting technology, we've expanded our impact into oncology in 2023 with a pioneering liquid biopsy test, Northstar, that combines treatment selection with monitoring. To date, over 500,000 patients have benefited from our innovative and precise diagnostic tests, and our Annual Recurring Revenue (ARR) has grown from $0 to $125 million in the last ~4 years.

BillionToOne has successfully raised close to $400 million in funding, with a notable $130 million Series D round completed in June 2024, resulting in a company valuation of over $1 billion. This funding has come from prestigious global institutional investors, including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest. BillionToOne has recently been recognized by Forbes as one of America's Best Startup Employers for 2024, highlighting the company's exceptional work environment and commitment to innovation.

Our team has grown significantly and we now proudly employ over 500 highly skilled individuals. Despite substantial growth, we have successfully maintained the unique culture that has defined BillionToOne from inception, continuing to cultivate a team that is not only diverse and passionate but also innovative. Headquartered in Menlo Park, California, with an additional facility in Union City, California, BillionToOne remains at the forefront of significant advances in molecular diagnostics, evidenced by the recent announcement of clinical outcomes data for its Unity Fetal Risk Screen and new advancements in cancer diagnostics. For more detailed information about BillionToOne and its groundbreaking work, please visit our website at www.billiontoone.com.

We are looking for a driven Pre-Analytical Supervisor to supervise the pre-analytical phase of testing for Northstar, BillionToOne’s Oncology product. This role involves supervising a team of Clinical Laboratory Associates performing specimen receipt, accessioning, sample preparation and processing, ensuring all processes adhere to the highest standards of quality and compliance. The Pre-Analytical Supervisor will play a crucial role in maintaining the efficiency and accuracy of our laboratory operations, contributing directly to the quality of our diagnostic products. This role is a full-time onsite position in Menlo Park, CA.

Shift Hours: Monday - Friday, 8:00 AM - 4:30 PM (occasional Saturdays)

Responsibilities:

• Supervise the pre-analytical phase of testing, including specimen receipt, accessioning, and sample preparation and processing
• Ensure all pre-analytical processes comply with CLIA/CAP regulations
• Train, mentor, and manage a team of pre-analytical staff, fostering a culture of quality and compliance
• Monitor workflow and ensure timely processing of specimens to meet TAT
• Develop, implement, and maintain standard operating procedures (SOPs) for pre-analytical activities
• Acting as a liaison between specimen handling, customer services, and various laboratory departments, the supervisor coordinates specimen receipt and  analytical and post-analytical phases with seamless communication and collaboration
• Perform quality assurance procedures and maintain accurate records of pre-analytical activities
• Troubleshoot and resolve issues related to specimen handling and processing
• Prepare and review controlled documents, including equipment maintenance logs and personnel records

Requirements:

• Bachelor’s degree in biology, molecular biology, or a related field
• Minimum of 2 years of experience in a clinical laboratory, with at least 1 year in a supervisory role. (molecular and/or high-complexity laboratory experience preferred)
• Strong understanding of molecular biology techniques, particularly in the context of NGS
• Self-starter and dynamic team player 
• Effective written and verbal communication skills
• Ability to multitask and work independently in a fast-paced environment
• Strong attention to detail and ability to work flexibly and well under given timeframes
• Familiarity with laboratory information management systems (LIMS), quality management systems (QMS), Google applications, and Microsoft Office

Nice-To-Haves:

• Experience in a start-up environment
• Advanced knowledge of DNA purification, PCR, electrophoresis, or next-generation sequencing
• Previous experience in a high-complexity clinical laboratory setting.

Benefits And Perks:

• Working with a team of ‘rockstars’ who bring out the best in everyone
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered at 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Retirement savings program including a 4% Company match
• Free daily on-site lunches provided from top eateries
• Latest and greatest hardware (laptop, lab equipment, facilities)
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, the base pay range is: $91,800-$112,200 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.