Senior Manager, Software Engineering, Oncology

BillionToOne is a next-generation molecular diagnostics company dedicated to developing powerful and accurate diagnostic tests that are accessible to all. Our innovative QCT molecular counting technology significantly enhances the resolution of disease detection using cell-free DNA by over a thousandfold. This groundbreaking technology is integral to our product offerings, including one of our flagship products, Unity Complete™, the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Leveraging the same molecular counting technology, we've expanded our impact into oncology in 2023 with a pioneering liquid biopsy test, Northstar, that combines treatment selection with monitoring. To date, over 500,000 patients have benefited from our innovative and precise diagnostic tests, and our Annual Recurring Revenue (ARR) has grown from $0 to $125 million in the last ~4 years.

BillionToOne has successfully raised close to $400 million in funding, with a notable $130 million Series D round completed in June 2024, resulting in a company valuation of over $1 billion. This funding has come from prestigious global institutional investors, including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest. BillionToOne has recently been recognized by Forbes as one of America's Best Startup Employers for 2024, highlighting the company's exceptional work environment and commitment to innovation.

Our team has grown significantly and we now proudly employ over 400 highly skilled individuals. Despite substantial growth, we have successfully maintained the unique culture that has defined BillionToOne from inception, continuing to cultivate a team that is not only diverse and passionate but also innovative. Headquartered in Menlo Park, California, with an additional facility in Union City, California, BillionToOne remains at the forefront of significant advances in molecular diagnostics, evidenced by the recent announcement of clinical outcomes data for its Unity Fetal Risk Screen and new advancements in cancer diagnostics. For more detailed information about BillionToOne and its groundbreaking work, please visit our website at www.billiontoone.com.

BillionToOne is looking for a Senior Manager, Software Engineering to lead development of customer-facing digital products, including clinician portals and EHR integrations for our rapidly growing oncology diagnostic testing products. BillionToOne’s DNA tests are at the forefront of personalized genomic medicine. Electronically integrating patient health data across disparate information silos and BillionToOne’s genomic testing results can enable oncologists to easily determine the most effective therapy or clinical trial for each patient. The Senior Manager, Software Engineering role is a full-time onsite position in our Menlo Park office. 

Examples of what you’ll work on include:

• Web-based portal that enables busy oncologists to order and receive state of the art DNA tests.
• Integrations with oncology practices’ EMR systems for seamless, “1-click” ordering of lab tests
• Clinical decision support systems to support oncologists as well as internal BillionToOne clinicians.
• Software systems to ingest unstructured and image-based medical data (e.g. clinical notes, CT scans) into a clinical data lake.

Technologies we use:

• Front-end: alpine.js, HTMX
• Backend: postgres, docker, python, Django, AWS, Heroku
• Healthcare Interop: HL7, FHIR, CCDA

Responsibilities:

• Manage the delivery and operation of high-quality software that enables clinician adoption of BillionToOne’s genetic tests
• Develop and implement software development processes and best practices to enhance team execution and ensure high-quality products. Use data to identify bottlenecks and improve them
• Provide hands-on leadership by example through designing, reviewing, and writing code
• Lead technical planning
• Collaborate with Design and Product Management to deliver efficient and informative
• Mentor and guide a team of 3-6 software engineers in their technical and professional development
• Manage the hiring process to bring on new talent as needed

Requirements:

• B.Sc/M.Sc degree in Computer Science or Bioinformatics
• 5+ years hands-on experience designing, building, and scaling consumer-facing web applications in digital health or diagnostics
• 3+ years of experience as a hands-on Software Engineering Manager
• Experience at 0-1 startups or growth companies preferred
• Strong knowledge of web technology across front-end and back-end: Javascript, React, Postgres, Python
• Strong knowledge of cloud architecture and devops (e.g. Docker, AWS, Sentry, Datadog)

Benefits And Perks:

• Working with a team of ‘rockstars’ who bring out the best in everyone
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered at 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Retirement savings program including a 4% Company match
• Free daily on-site lunches provided from top eateries
• Latest and greatest hardware (laptop, lab equipment, facilities)
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses) (2) generous equity options offering, on top of (3) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave etc.).

For this position, we offer a total compensation package of $375,000 per year, including a base pay range of $200,000-$230,000 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.