Ready to redefine what's possible in molecular diagnostics?

Join a team of brilliant, passionate innovators who wake up every day determined to transform healthcare. At BillionToOne, we've built something extraordinary—a culture where transparency fuels trust, collaboration drives breakthroughs, and every voice matters in our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we strive to build products that are 10x better than anything that exists today. Our people are our greatest asset: talented scientists, engineers, sales professionals, and visionaries united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion—every innovation you contribute helps remove fear of unknown from some of life's most critical medical moments. If you're driven by purpose, energized by innovation, and ready to help build the future of precision medicine, this is where you belong.

We are seeking an Automation Service Engineer I, Oncology to provide service support to the laboratory operations team and to be responsible for troubleshooting, maintenance, and repair of laboratory equipment utilized. This position requires a candidate that is strong in root cause analysis, application support and repair of equipment commonly used in the Next Generation Sequencing workflow. The role requires a detail-oriented candidate with experience in a regulated environment, exceptional documentation (GDP) abilities and strong written and verbal communication skills. This is an onsite position in our facility in Menlo Park, CA.

Shift Schedule: Tuesday-Saturday AM

Responsibilities:

• Provide service, support, and troubleshooting for automated processes and instrumentation.
• Perform and coordinate maintenance work on laboratory equipment.
• Troubleshoot, conduct root cause analysis, and problem solving on lab instruments.
• Carry out Installation, Operational, and Process Qualifications on new equipment as necessary.
• Collaborate with Quality Control to ensure all documentation is completed accurately and in accordance with regulatory requirements.
• Effectively coordinate with vendors as required for equipment issues.
• Maintain equipment parts inventory and well-organized equipment records.
• Prepare documentation as needed for equipment operation and maintenance.
• Propose and design plans for process improvements.
• Represent the equipment and automation teams in cross-functional meetings.
• Undertake special projects as assigned.

Requirements:

• BS degree in a scientific discipline.
• 2+ years of experience in operating and troubleshooting laboratory equipment, preferably high-throughput molecular biology equipment, especially liquid handlers.
• Strong customer focused service experience.
• Ability to engage in constructive dialogue, challenge concerns and maintain transparency.
• Proficiency in problem-solving with limited direction and making confident decisions.
• Attention to detail and accuracy.
• Solid understanding of statistical analyses relevant to automated lab processes.
• Strong multi-tasking ability with a focus on prioritization.
• Experience in troubleshooting complex scripts is an added advantage.
• Experience working in a CLIA or similar regulated environment is preferred.
• Ability to work effectively in a team and build strong relationships.
• Self-motivated with a high level of initiative.
• Drive for continual improvement.

Nice-to-Haves:

• Familiarity with Molecular Biology techniques, including next generation sequencing.
• Experience with data science / data engineering in an automated laboratory environment.
• Experience developing training programs and performing knowledge transfer.

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package range of up to $146,969 per year, including a base pay rate of $48.23 - $53.31 per hour.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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About BillionToOne

BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA—a breakthrough that's already transformed the lives of over half a million patients worldwide.

Our Impact: We've pioneered game-changing diagnostic solutions that are redefining industry standards. Unity Complete™ stands as the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. In oncology, our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

Our Growth: From $0 to $125 million in Annual Recurring Revenue in just four years. We've raised close to $400 million in funding, including a $130 million Series D round in June 2024, achieving a valuation of over $1 billion. This backing comes from world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Our Recognition: Forbes recently named us one of America's Best Startup Employers for 2025, and we were awarded Great Place to Work certification in 2024—with an incredible 100% of our people reporting they are willing to give extra to get the job done. These honors recognize not just our innovation but the exceptional culture we've cultivated—one that remains authentically collaborative and transparent even as we've scaled.

Our Future: Headquartered in Menlo Park with facilities in Union City, California, we're continuing to push the boundaries of what's possible in molecular diagnostics. Recent clinical outcomes data for Unity Fetal Risk Screen and new advances in cancer diagnostics prove we're just getting started.

At BillionToOne, you'll join a diverse team of passionate innovators who believe that the best science happens when brilliant minds collaborate openly, think boldly, and never lose sight of the patients whose lives depend on our work.

Ready to help us change the world, one diagnosis at a time?

Learn more at www.billiontoone.com