Senior Automation Scientist

BillionToOne is a next-generation molecular diagnostics company dedicated to developing powerful and accurate diagnostic tests that are accessible to all. Our innovative QCT molecular counting technology significantly enhances the resolution of disease detection using cell-free DNA by over a thousandfold. This groundbreaking technology is integral to our product offerings, including one of our flagship products, Unity Complete™, the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Leveraging the same molecular counting technology, we've expanded our impact into oncology in 2023 with a pioneering liquid biopsy test, Northstar, that combines treatment selection with monitoring. To date, over 500,000 patients have benefited from our innovative and precise diagnostic tests, and our Annual Recurring Revenue (ARR) has grown from $0 to $125 million in the last ~4 years.

BillionToOne has successfully raised close to $400 million in funding, with a notable $130 million Series D round completed in June 2024, resulting in a company valuation of over $1 billion. This funding has come from prestigious global institutional investors, including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest. BillionToOne has recently been recognized by Forbes as one of America's Best Startup Employers for 2024, highlighting the company's exceptional work environment and commitment to innovation.

Our team has grown significantly and we now proudly employ over 400 highly skilled individuals. Despite substantial growth, we have successfully maintained the unique culture that has defined BillionToOne from inception, continuing to cultivate a team that is not only diverse and passionate but also innovative. Headquartered in Menlo Park, California, with an additional facility in Union City, California, BillionToOne remains at the forefront of significant advances in molecular diagnostics, evidenced by the recent announcement of clinical outcomes data for its Unity Fetal Risk Screen and new advancements in cancer diagnostics. For more detailed information about BillionToOne and its groundbreaking work, please visit our website at www.billiontoone.com.

We are seeking a Senior Scientist of Automation - Oncology to join our dynamic Oncology Development team. This individual contributor role will lead development projects with automation initiatives to scale our high-complexity and high-growth clinical laboratory for groundbreaking oncology tests, focusing on developing processes and launching larger-scale versions of our products in the development pipeline. The successful candidate should have a strong background in chemistry and engineering, with preferred expertise in data analysis and/or bioinformatics. You will work closely with interdisciplinary teams to design and integrate innovative solutions that enhance product development and scalability within our oncology diagnostics. This role requires the majority of days to be spent onsite at the Menlo Park location and reports to the Associate Director of Development, Oncology.

Responsibilities:

• Develop and optimize processes for launching larger-scale versions of oncology diagnostics products in the development pipeline.
• Collaborate with R&D, bioinformatics, process engineering and CLIA teams, to innovate and implement solutions that integrate seamlessly into product development workflows.
• Lead initiatives to develop automation solutions that support the design and scalability of new assays and diagnostic features.
• Utilize data analysis and bioinformatics skills to support test development and refinement, ensuring accuracy and precision.
• Work within the interdisciplinary development team and contribute to the development of scalable diagnostic tests.
• Maintain comprehensive documentation, including experimental designs, process optimizations, validations, and standard operating procedures.
• Present progress on development projects and strategies for product scale-up to senior leadership.

Requirements:

• PhD in Chemistry, Engineering, Biophysics, Biochemistry, Bioengineering or a related field.
• Strong skills in statistical modeling and first-principle thinking.
• 3+ years of experience in a research or industry setting, with a focus on automation engineering or process development.
• Experience with liquid handling systems (Agilent Bravo, Hamilton STAR, Biomek, etc.) and/or next-generation sequencing technologies.
• Proficiency in coding languages such as Python or R.
• Excellent analytical and communication skills, with the ability to clearly convey complex scientific concepts.
• Ability to collaborate across scientific disciplines to develop integrated and scalable solutions.

Nice-to-Haves:

• Strong background in data analysis and/or bioinformatics.
• Experience working in regulated environments (CLIA, CAP, FDA).
• Experience with laboratory information management systems (LIMS).
• Six Sigma or Lean certification.

Benefits And Perks:

• Working with a team of ‘rockstars’ who bring out the best in everyone
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousand patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered at 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Retirement savings program including a 4% Company match
• Free daily on-site lunches provided from top eateries
• Latest and greatest hardware (laptop, lab equipment, facilities)
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $240,000 per year, including a base pay range of $130,000 - $150,000 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.