Ready to redefine what's possible in molecular diagnostics?

Join a team of brilliant, passionate innovators who wake up every day determined to transform healthcare. At BillionToOne, we've built something extraordinary—a culture where transparency fuels trust, collaboration drives breakthroughs, and every voice matters in our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we strive to build products that are 10x better than anything that exists today. Our people are our greatest asset: talented scientists, engineers, sales professionals, and visionaries united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion—every innovation you contribute helps remove fear of unknown from some of life's most critical medical moments. If you're driven by purpose, energized by innovation, and ready to help build the future of precision medicine, this is where you belong.

We are looking for a LIMS Administrator to join our growing Process Engineering team in the Oncology division to support clinical patient testing in our CLIA lab. The LIMS Administrator will be responsible for (1) Evolving the sophistication and usage of the company’s LIMS tools to support rapid scaling of our clinical lab, (2) Identifying needs and implementing changes to expand the scope of use and the capabilities of LIMS software within lab, (3) Managing a relationship with third party developers and our internal engineering team in system integration efforts, and (4) Working with our process service, and automation engineers to improve laboratory processes, and (5) Streamlining and expanding data export capabilities and integration of LIMS data with our data science team.

This role will help to build upon the strong technology and execution found within BTO’s walls, and will help us pave the way for replicating our prenatal success in the oncology space. This is considered an onsite role and will require the majority of days to be spent in the office at either the Menlo Park or Union City sites. 

Responsibilities:

• Serve as the primary company liaison to Semaphore Solutions, the external develop of the Labbit LIMS 
• Collaborate closely with wet lab scientists in our clinical molecular biology lab to understand workflows and the corresponding data flow needs
• Perform routine LIMS systems and software maintenance procedures Collaborate with SMEs to design & implement LIMS workflows & to support new assay launches
• Manage existing LIMS workflows, their operations, lifecycle and data
• Manage full release process, including validation, coordination of training, completion of required documentation, and deployments
• Manage relationships with third party contractors & developers, including running weekly meetings, enforcing deadlines, and tracking contracted hours of work
• Monitor, troubleshooting, and correct systems and software technical issues (e.g. resolving bugs and LIMS outages)
• Triage & escalate unresolved technical issues to appropriate internal teams or external developers
• Network with internal stakeholders & customers to develop new technologies
• Develop and maintain relevant technical documentation (SOPs, Policies, etc) for use of BTO’s LIMS systems. 
• Ensure compliance to all relevant corporate and regulatory requirements
• Provide end-to-end support & ownership for tickets requiring system change
• Train SMEs across Software Engineering, Data Science, and CLIA to understand LIMS API and data warehouse
• Work with product management teams to maintain and prioritize a backlog of work for information management systems
• Perform periodic review of LIMS performance and report out to senior leadership
• Onboard personnel to LIMS and define systems, roles, and responsibilities
• Set yearly and quarterly goals for Labbit LIMS
• Prioritize and scope features based on goals and timelines
• Define and measure KPIs for Labbit LIMS

Requirements:

• Bachelor's degree in Computer Science, Software or Information Systems or equivalent technical expertise with information systems
• 2-5 Years' Experience with Laboratory Information Systems (LIS) 
• 2-4 Years' Experience working in a CLIA Lab, medical device, or pharma environment
• Comfortable working with cross-functional teams across CLIA, Process Engineering, Software Engineering, Automation and Service Engineering, Data Science, Supply Chain, and Product
• Excellent ability to communicate with CLIA lab personnel to understand molecular biology workflows, regulatory compliance needs and real-world laboratory challenges
• Experience with diagramming workflows using tools such as Lucidchart, Visio, etc.
• Ability to troubleshoot and diagnose basic technical issues 
• Deep familiarity with structured data types, including JSON
• Experience with REST APIs 
• Experience with Bash
• Experience with Python
• Experience developing scripting solutions to automation problems, especially in a fast paced/agile setting
• Strong attention to detail and ability to work flexibly and well under given timeframes
• Highly organized, strong written and verbal communicator
• Excellent problem-solving and communication skills 
• Strong project management skills and familiarity with project management tools such as Jira, Notion, etc. 
• Experience with support

Nice-To-Haves:

• Experience with Illumina NGS workflows
• Experience with molecular biology workflows in a high-throughput environment
• Experience with automated liquid handlers and software integrations
• Familiarity with AWS S3
• Familiarity with cloud applications and with EC2
• Experience with the Labbit LIMS platform
• Direct experience with multiple LIMS products (Clarity, STARLIMS, Labvantage, Labworks, etc)
• Familiarity with Quality Management Systems such as Arena and with related regulations (CFR 21 Part 11, ISO 13485, etc) 
• Experience with data analysis using Excel, SQL, R, and/or Python
• Experience with bioinformatics pipelines

Benefits And Perks:

• Working with a team of ‘rockstars’ who bring out the best in everyone
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousand patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered at 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Retirement savings program including a 4% Company match
• Free daily on-site lunches provided from top eateries
• Latest and greatest hardware (laptop, lab equipment, facilities)
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $201,666 per year, including a base pay range of $135,252 - $156,060 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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About BillionToOne

BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA—a breakthrough that's already transformed the lives of over half a million patients worldwide.

Our Impact: We've pioneered game-changing diagnostic solutions that are redefining industry standards. Unity Complete™ stands as the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. In oncology, our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

Our Growth: From $0 to $125 million in Annual Recurring Revenue in just four years. We've raised close to $400 million in funding, including a $130 million Series D round in June 2024, achieving a valuation of over $1 billion. This backing comes from world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Our Recognition: Forbes recently named us one of America's Best Startup Employers for 2025, and we were awarded Great Place to Work certification in 2024—with an incredible 100% of our people reporting they are willing to give extra to get the job done. These honors recognize not just our innovation but the exceptional culture we've cultivated—one that remains authentically collaborative and transparent even as we've scaled.

Our Future: Headquartered in Menlo Park with facilities in Union City, California, we're continuing to push the boundaries of what's possible in molecular diagnostics. Recent clinical outcomes data for Unity Fetal Risk Screen and new advances in cancer diagnostics prove we're just getting started.

At BillionToOne, you'll join a diverse team of passionate innovators who believe that the best science happens when brilliant minds collaborate openly, think boldly, and never lose sight of the patients whose lives depend on our work.

Ready to help us change the world, one diagnosis at a time?

Learn more at www.billiontoone.com