Senior Automation Associate, Oncology

BillionToOne is a next-generation molecular diagnostics company dedicated to developing powerful and accurate diagnostic tests that are accessible to all. Our innovative QCT molecular counting technology significantly enhances the resolution of disease detection using cell-free DNA by over a thousandfold. This groundbreaking technology is integral to our product offerings, including one of our flagship products, Unity Complete™, the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Leveraging the same molecular counting technology, we've expanded our impact into oncology in 2023 with a pioneering liquid biopsy test, Northstar®, that combines treatment selection with monitoring. To date, over 500,000 patients have benefited from our innovative and precise diagnostic tests, and our Annual Recurring Revenue (ARR) has grown from $0 to $125 million in the last ~4 years.

BillionToOne has successfully raised close to $400 million in funding, with a notable $130 million Series D round completed in June 2024, resulting in a company valuation of over $1 billion. This funding has come from prestigious global institutional investors, including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest. BillionToOne has recently been recognized by Forbes as one of America's Best Startup Employers for 2025, highlighting the company's exceptional work environment and commitment to innovation.

Our team has grown significantly and despite substantial growth, we have successfully maintained the unique culture that has defined BillionToOne from inception, continuing to cultivate a team that is not only diverse and passionate but also innovative. Headquartered in Menlo Park, California, with an additional facility in Union City, California, BillionToOne remains at the forefront of significant advances in molecular diagnostics, evidenced by the recent announcement of clinical outcomes data for its Unity Fetal Risk Screen and new advancements in cancer diagnostics. For more detailed information about BillionToOne and its groundbreaking work, please visit our website at www.billiontoone.com.

We are seeking a Senior Development Associate, Automation – Oncology to join our dynamic Oncology Development team. As a key technical contributor, you will support the development and optimization of assays and automation processes to scale our high-complexity and high-growth clinical laboratory for groundbreaking oncology tests. You will work closely with interdisciplinary teams to implement and refine processes that integrate chemistry changes,, liquid handling automation, and algorithm refinement, contributing to the advancement and scalability of our oncology diagnostics products. This role is primarily onsite at our Menlo Park location and reports to the Sr. Automation Scientist, Development, Oncology.

Responsibilities:

• Support the development and optimization of molecular biology processes for larger-scale oncology diagnostics products in the development pipeline.
• Collaborate with Research, bioinformatics, process engineering, and CLIA teams to implement solutions that integrate into product development workflows and production facilities.
• Contribute to the development and implementation of automation solutions for new assays and diagnostic features.
• Assist with data analysis and bioinformatics tasks to support test development and refinement, ensuring accuracy and precision.
• Work as part of an interdisciplinary team to help develop scalable diagnostic tests.
• Maintain comprehensive documentation, including experimental designs, process optimizations, validations, and standard operating procedures.
• Present updates on assigned tasks and project progress to team members and management.

Requirements:

• Bachelor’s or Master’s degree (preferred) in Chemistry, Engineering, Biophysics, Biochemistry, Bioengineering, or a related field.
• Strong skills in statistical and first-principle thinking.
• 1–3 years of experience in a research or industry setting, preferably with exposure to automation engineering or process development.
• Experience with liquid handling systems (Agilent Bravo, Hamilton STAR, Biomek, etc.) and/or next-generation sequencing technologies is a plus.
• Proficiency in coding languages such as Python, Java, and strong data analysis skills.
• Excellent analytical and communication skills, with the ability to clearly convey scientific and engineering concepts.
• Ability to collaborate effectively with others within the team and across different teams.

Nice-to-Haves:

• Molecular biology/nucleic acid chemistry experience.
• Background in bioinformatics.
• Experience working in regulated environments (CLIA, CAP, FDA).
• Experience with laboratory information management systems (LIMS).

Benefits And Perks:

• Working with a team of ‘rockstars’ who bring out the best in everyone
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousand patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered at 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Retirement savings program including a 4% Company match
• Free daily on-site lunches provided from top eateries
• Latest and greatest hardware (laptop, lab equipment, facilities)
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $112,750 per year, including a base pay range of $83,232 - $93,636 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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