Ready to redefine what's possible in molecular diagnostics?

Join a team of brilliant, passionate innovators who wake up every day determined to transform healthcare. At BillionToOne, we've built something extraordinary—a culture where transparency fuels trust, collaboration drives breakthroughs, and every voice matters in our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we strive to build products that are 10x better than anything that exists today. Our people are our greatest asset: talented scientists, engineers, and visionaries united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion—every innovation you contribute helps remove fear of unknown from some of life's most critical medical moments. If you're driven by purpose, energized by innovation, and ready to help build the future of precision medicine, this is where you belong.

BillionToOne is seeking a Finance Systems Manager who will play a pivotal role in driving technology solutions across our finance function. This is a hands-on manager-level role, responsible for the administration, optimization, and integration of financial systems to support scaling operations and compliance with public company standards.

You’ll act as the key liaison between Finance, HR, Billing, and IT to ensure that systems and projects are aligned with business goals and internal control requirements. Your expertise in ERP systems, audit compliance, and cross-functional collaboration will be essential in enhancing the efficiency, accuracy, and control of our financial processes. The Finance System Manager is a hybrid position (Menlo Park or Union City, CA) and will report to the VP, Information Systems.

Responsibilities:

• Technology Integration & System Management
  • Oversee the implementation and integration of financial technologies, including ERP systems, revenue and payment systems.
  • Serve as the system administrator for NetSuite, managing configurations, workflows, roles, and user access.
  • Work with the Accounting and Supply Chain teams to project manage and implement new features and systems. 
  • Identify and drive automation and process improvement opportunities across finance and supply chain systems.
  • Collaborate with internal stakeholders to ensure system design aligns with operational and compliance requirements.
  • Manage data integrations with financial systems 
• Cross-Functional Collaboration
  • Act as a liaison between Accounting, HR, and IT, ensuring business needs are accurately translated into technical solutions.
  • Partner with the Accounting team during monthly/quarterly close and audits to ensure system readiness and data integrity.
  • Support Accounting, HR with planning tools integration and reporting needs.
  • Write system requirements documents, write and manage change requests and project manage finance systems projects.
• Compliance & Controls
  • Maintain systems and processes in alignment with internal control frameworks and SOX readiness efforts (404a or 404b).
  • Support audit processes by ensuring finance systems provide required traceability, accuracy, and documentation. Write and manage all IT SOX documentation.

Qualifications:

• 5+ years of hands-on NetSuite system administration experience supporting Finance and Supply Chain.
• 2+ years of experience supporting financial audits in a public company environment (404b) and has worked with public company audit.
• Bachelor’s degree in Accounting, Computer Science, Information Systems, or a related field.
• Demonstrated ability to manage and implement finance system projects from end to end.
• Strong understanding of financial operations, reporting, and internal controls.
• Comfortable working in a fast-paced, dynamic environment with cross-functional teams.
• Experience working with SOX systems such as HRIS, Equity Management etc.
• Excellent problem-solving and analytical skills.
• Strong leadership and team management capabilities.
• Ability to work independently and manage multiple projects simultaneously.
• Effective communication skills, with the ability to convey complex data insights to non-technical stakeholders.
• Detail-oriented with a commitment to producing high-quality, accurate work.
• Ability to thrive in a fast-paced, high growth, dynamic environment and manage multiple priorities.

Nice to Have:

• Familiarity with data integration tools (e.g., Mulesoft).
• Experience with ADP WorkForce Now and other HRIS systems.

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About BillionToOne

BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA—a breakthrough that's already transformed the lives of over 500,000 patients worldwide.

Our Impact: We've pioneered game-changing diagnostic solutions that are redefining industry standards. Unity Complete™ stands as the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. In oncology, our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

Our Growth: From $0 to $125 million in Annual Recurring Revenue in just four years. We've raised close to $400 million in funding, including a $130 million Series D round in June 2024, achieving a valuation of over $1 billion. This backing comes from world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Our Recognition: Forbes recently named us one of America's Best Startup Employers for 2025, and we were awarded Great Place to Work certification in 2024—with an incredible 100% of our people reporting they are willing to give extra to get the job done. These honors recognize not just our innovation but the exceptional culture we've cultivated—one that remains authentically collaborative and transparent even as we've scaled.

Our Future: Headquartered in Menlo Park with facilities in Union City, California, we're continuing to push the boundaries of what's possible in molecular diagnostics. Recent clinical outcomes data for Unity Fetal Risk Screen and new advances in cancer diagnostics prove we're just getting started.

At BillionToOne, you'll join a diverse team of passionate innovators who believe that the best science happens when brilliant minds collaborate openly, think boldly, and never lose sight of the patients whose lives depend on our work.

Ready to help us change the world, one diagnosis at a time?

Learn more at www.billiontoone.com