Ready to redefine what's possible in molecular diagnostics?

Join a team of brilliant, passionate innovators who wake up every day determined to transform healthcare. At BillionToOne, we've built something extraordinary—a culture where transparency fuels trust, collaboration drives breakthroughs, and every voice matters in our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we strive to build products that are 10x better than anything that exists today. Our people are our greatest asset: talented scientists, engineers, sales professionals, and visionaries united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion—every innovation you contribute helps remove fear of unknown from some of life's most critical medical moments. If you're driven by purpose, energized by innovation, and ready to help build the future of precision medicine, this is where you belong.

We are seeking an experienced and hands-on Manager / Senior Manager of EMR Integrations & Interoperability to lead the delivery and ongoing improvement of our EMR integration capabilities. This role plays a key part in supporting our provider-facing technology, helping improve clinical workflows, operational efficiency, and client satisfaction.

In this role, you will manage EMR integration projects end-to-end—from implementation planning to production support—while ensuring solutions meet business and technical requirements. You’ll collaborate closely with Product, Engineering, Clinical Operations, and Commercial teams to align integration work with organizational priorities.

This is a hands-on leadership position for someone with strong healthcare IT and EMR systems experience, who enjoys managing teams and projects while contributing directly to technical execution.

Responsibilities:

• Strategic Leadership
  • Define and execute the enterprise-wide EMR integration strategy, aligning with clinical, commercial, and product goals.
  • Develop and own the long-term roadmap for scalable, secure, and interoperable EMR integration infrastructure.
  • Serve as a thought leader on EMR interoperability, standards (e.g., HL7, FHIR, SMART), and vendor ecosystems.
• Team Leadership & Organizational Development
  • Manage and mentor a team of EMR integration engineers, analysts, and/or project managers.
  • Support hiring, onboarding, and development of team members.
  • Foster a collaborative, accountable, and high-performance team culture.
  • Establish and evolve team processes, performance standards, and professional development frameworks.
• Technical & Operational Execution
  • Oversee the full lifecycle of EMR integrations across Epic, Cerner, Athena, and other major platforms—from initial scoping to go-live and long-term support.
  • Lead the team in designing, configuring, and optimizing EMR workflows, data exchange protocols, and custom interfaces.
  • Set and enforce best practices for security, scalability, and compliance (e.g., HIPAA, HITRUST).
  • Develop proactive monitoring, alerting, and incident response protocols for production environments.
• Cross-Functional Collaboration & Communication
  • Partner closely with Product, Engineering, Sales, and Clinical teams to align integration efforts with broader business objectives.
  • Represent the EMR integration function in executive meetings, client engagements, and industry conferences.
  • Provide regular updates to executive leadership, including KPIs, integration performance metrics, and risk assessments.

Qualifications:

• 6+ years of experience in healthcare IT, EMR integration, or clinical interoperability, including at least 2–3 years in a people or project leadership role.
• Solid technical expertise in major EMR platforms and interoperability standards (e.g., HL7, FHIR, CDA, SMART on FHIR, APIs).
• Proven track record in delivering complex integration projects on time and within scope.
• Experience managing small-to-mid-sized technical teams.
• Strong communication and stakeholder management skills across technical and non-technical groups.
• Familiarity with agile project management and SDLC best practices.
• Bachelor’s degree in Computer Science, Health Informatics, Biomedical Engineering, or related field preferred.

Benefits And Perks:

• Working with a team of ‘rockstars’ who bring out the best in everyone
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousand patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered at 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Retirement savings program including a 4% Company match
• Free daily on-site lunches provided from top eateries
• Latest and greatest hardware (laptop, lab equipment, facilities)
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of (1) competitive base pay, (2) the opportunity for professional growth, and (3) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave etc.).

For this position, we offer a total compensation package of up to $306,095 per year, including a base pay range of $145,656 - $192,474 per year.

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About BillionToOne

BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA—a breakthrough that's already transformed the lives of over half a million patients worldwide.

Our Impact: We've pioneered game-changing diagnostic solutions that are redefining industry standards. Unity Complete™ stands as the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. In oncology, our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

Our Growth: From $0 to $125 million in Annual Recurring Revenue in just four years. We've raised close to $400 million in funding, including a $130 million Series D round in June 2024, achieving a valuation of over $1 billion. This backing comes from world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Our Recognition: Forbes recently named us one of America's Best Startup Employers for 2025, and we were awarded Great Place to Work certification in 2024—with an incredible 100% of our people reporting they are willing to give extra to get the job done. These honors recognize not just our innovation but the exceptional culture we've cultivated—one that remains authentically collaborative and transparent even as we've scaled.

Our Future: Headquartered in Menlo Park with facilities in Union City, California, we're continuing to push the boundaries of what's possible in molecular diagnostics. Recent clinical outcomes data for Unity Fetal Risk Screen and new advances in cancer diagnostics prove we're just getting started.

At BillionToOne, you'll join a diverse team of passionate innovators who believe that the best science happens when brilliant minds collaborate openly, think boldly, and never lose sight of the patients whose lives depend on our work.

Ready to help us change the world, one diagnosis at a time?

Learn more at www.billiontoone.com