Staff Data Scientist, Reasoning

Biohub is a 501(c)(3) biomedical research organization building the first large-scale scientific initiative combining frontier AI with frontier biology to solve disease. We build the technology to help scientists around the world use AI-powered biology to study how cells operate, organize, and work as part of systems to understand why disease happens and how to correct it. With our compute capacity, AI research and engineering, and state-of-the-art technology for measuring, imaging, and programming biology, we are enabling scientists worldwide to use AI-powered biology to advance our understanding of human health.

The Team

Our AI research team sits at the heart of our mission to unlock new dimensions of biological understanding. You will leverage state-of-the-art AI to accelerate discovery and drive transformative insights in biology—developing novel AI models purpose-built for biological research, engineering robust systems that enable breakthrough science at unprecedented scale, and translating these advances into practical tools that empower researchers worldwide.

Our approach is comprehensive and integrated, bringing together world-class AI model development, exceptional engineering talent, high-quality biological sciences and data, powerful computing infrastructure, and strategic partnerships. Success requires excellence across five interconnected pillars: training frontier AI models specifically for biology; building engineering systems that maximize research velocity and efficiency; executing a sophisticated biological and data strategy that fuels AI development; operating a world-class AI compute platform; and creating impactful products that transform AI capabilities into accessible scientific tools.

The Opportunity

This is an opportunity to shape the future of biological research by pushing the boundaries of what AI can achieve in science. You’ll work alongside leading experts in AI and biology, with the resources and mandate to tackle some of the most important questions in human health — advancing frontier AI research, accelerating engineering velocity, connecting rich biological data to AI systems, enabling reliable compute across environments, and translating models and data into usable, scalable applications that drive scientific impact.

The role is part of the Data team, which is responsible for maximizing the speed, agility, and capability of biological AI research by connecting public data resources and Biohub's experimental platforms to AI systems. The data that trains biological frontier models comes in dozens of modalities (sequences, images, spatial coordinates, time series, molecular structures, metadata, publication artifacts, …) each with its own noise characteristics, biases, and information content. The question of how AI can reason across these diverse descriptions of biology to answer specific experimental questions is one of the core challenges in biology.

You will define the data approach to train our reasoning system. To do so, you will operate with broad scope and high autonomy, influencing roadmap decisions across teams while mentoring individual contributors. Success in this role means scaling data systems that are not only large, but adaptive, interpretable, and scientifically grounded, accelerating progress toward robust biological frontier models and ultimately advancing human health. We're looking for data scientists who can work at this frontier: people who understand scientific experimentation deeply, think creatively about data representations and tokenization strategies, and have experience building reasoning systems. You'll work directly with experimental and computational scientists, data scientists and AI researchers to define what the models see and how they see it, and data engineers to make this work at scale. This is a role for someone who wants to invent the methods that make biological frontier models possible.

What You'll Do

• Design reasoning tasks for our models.
• Build training datasets that capture biology experiments, including experimental design, hypothesis generation, evidence interpretation, and scientific inference
• Design training strategies that teach reasoning capabilities, working closely with AI Research to translate data approaches into model behavior
• Create evaluation and benchmarking frameworks that measure reasoning quality and analyze model behavior to influence the next set of evaluations, environments, and data.
• Partner with Scientific Data Strategy and Data Engineering to identify and acquire source materials (literature, protocols, experimental records) that contain reasoning signal
• Set technical direction for reasoning data efforts, influencing priorities and mentoring other data scientists working in this area

What You'll Bring

• PhD in machine learning, computational biology, or another quantitative field
• Hands on understanding of how scientists reason across diverse experimental systems as obtained from hands-on experience with laboratory science in biology, biochemistry, or chemistry
• Experience curating or creating training data and tokenization strategies for reasoning models (RLVR, synthetic reasoning traces, RL with Tool Use)
• Track record of novel methodological contributions (publications, open-source tools, or production systems)
• Familiarity with evaluation methodology for complex, open-ended tasks where ground truth is ambiguous
• Strong computational skills (Python, data processing at scale); ability to work with large text corpora and structured data
• Creative, first-principles thinking about how to structure data for learning

Compensation

The Redwood City, CA & New York City, NY base pay range for a new hire in this role is $214,000 - $268,000. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process. 

Better Together

As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager's discretion and communicated during the interview process.

Benefits for the Whole You 

We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible. 

• Provides a generous employer match on employee 401(k) contributions to support planning for the future.
• Paid time off to volunteer at an organization of your choice. 
• Funding for select family-forming benefits. 
• Relocation support for employees who need assistance moving

If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.

#LI-Hybrid