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Scientist - Virus Host Interactions (Arias Group)

San Francisco, California, United States

The Chan Zuckerberg Biohub San Francisco (CZ Biohub SF) (https://www.czbiohub.org/sf/) is an independent nonprofit research institute that brings together three powerhouse universities - Stanford, UC Berkeley, and UC San Francisco - into a single collaborative technology and discovery engine. CZ Biohub SF itself supports some of the brightest, boldest engineers, data scientists, and biomedical researchers to investigate the fundamental mechanisms underlying disease and develop new technologies that will lead to actionable diagnostics and effective therapies. We are guided by our values of scholarly excellence; disruptive innovation; hands-on engineering/hacking/building; partnership and collaboration; open communication and respect; inclusiveness; and opportunity for all.

Our Vision

  • We pursue large scientific challenges that cannot be pursued in conventional environments
  • We enable individual investigators to pursue their riskiest and most innovative ideas
  • The technologies developed at CZ Biohub San Francisco facilitate research by scientists and clinicians at our home institutions and beyond

Diversity of thought, ideas, and perspectives are at the heart of CZ Biohub Network and enable disruptive innovation and scholarly excellence. We are committed to cultivating an inclusive organization where all colleagues feel inspired and know their work makes an important contribution.

The Opportunity

The Arias Group (https://www.czbiohub.org/arias/) at CZ Biohub San Francisco explores the molecular mechanisms of virus–host interactions in cells infected with medically relevant viruses. Our overarching objective is to reveal molecular dependencies that can be targeted for developing broad-spectrum antivirals. We actively collaborate with virology, cell biology, genomics, proteomics, microscopy, and data science teams across CZ Biohub San Francisco

We invite a dynamic and dedicated Scientist to enrich our team, someone keen to explore the intricate molecular interplay within virus-infected cells. This role is a confluence of multiomics analysis, comparative virology, and bioinformatics to uncover the mechanisms viruses use to hijack cellular machinery and identify potential targets for antiviral therapies.

The application requires a cover letter that includes your interest in this role, the contributions you are excited to make, the skills you want to strengthen on the job, your professional goals, and how this role can help you achieve them.

What You'll Do 

  • Design, conduct, and analyze multiomics (transcriptomics and proteomics) experiments in virus-infected cells
  • Establish, optimize, and troubleshoot comparative virology experiments
  • Collaborate with multidisciplinary teams of virologists, cell biologists, computational microscopists, and genomics and proteomics experts
  • Collaborate with data sciences teams to integrate multiomic data, enhancing understanding of viral infection mechanisms
  • Ensure meticulous record-keeping of experimental workflows, findings, and analytical data
  • Disseminate findings through scientific publications and presentations at internal, local, and international conferences
  • Actively participate in the publication process, from manuscript preparation to submission in peer-reviewed journals and open-access platforms
  • Contribute to disseminating research findings by depositing software and datasets in recognized repositories
  • Stay updated with the latest molecular biology and multiomics techniques relevant to viral research
  • Provide guidance and mentorship to junior team members, fostering a nurturing learning environment

What You'll Bring

Essential –

  • Hold a Ph.D. in a relevant field with 1-2 years of post-Ph.D. experience, and at least 5 years of research experience
  • At least 4 years of experience in virology and general molecular biology techniques
  • Robust experience in RNA sequencing (bulk and single-cell) and proteomics methods
  • Strong relationship-, community-building and interpersonal skills
  • Excellent written and verbal communication skills
  • Excellent professional judgment, problem-solving skills, and the ability to work independently and as part of a team.
  • Organizational skills and the flexibility to jump between projects and priorities

 Nice to have -

  • Proficiency in bioinformatics, with hands-on experience in R and/or Python programming languages

The Chan Zuckerberg Biohub Network requires all employees, regardless of work location or type of role, to provide proof of their initial COVID-19 vaccination by their start date. Those who are unable to get vaccinated because of a disability, or who choose not to be vaccinated due to a sincerely held religious belief, practice, or observance must have an approved exception prior to their start date.

Compensation

  • Scientist I =  $100,000 - $137,500
  • Scientist II = $112,000 - $154,000

New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. To determine starting pay, we consider multiple job-related factors including a candidate’s skills, education and experience, market demand, business needs, and internal parity. We may also adjust this range in the future based on market data. Your recruiter can share more about the specific pay range during the hiring process.

What We Provide

  • Resources to disrupt and innovate at the frontiers of our knowledge of biology and disease
  • A collegial and collaborative environment consisting of diverse expertise
  • Existing collaborations within CZ Biohub: Technology Platforms (Bioengineering, Computational Microscopy, Data Science, Genomic Sequencing, Mass Spectrometry/Proteomics), and Research Group Leaders
  • Access to collaborators, resources and facilities at our three partner universities (Stanford, UC Berkeley, and UC San Francisco) and at partner organizations in the Bay Area and beyond
  • Competitive compensation and benefits commensurate with experience

Benefits

We offer a robust benefits program that enables the important work Biohubbers do everyday. Our benefits include healthcare coverage, life and disability insurance, commuter subsidies, family planning services with fertility care, childcare stipend, 401(k) match, flexible time off and a generous parental leave policy. In addition, we honor our commitment to career development and our value of scholarly excellence through regular onsite opportunities to learn from the world's leading scientists.

The CZ Biohub Network is an equal opportunity employer committed to diversity of thought, ideas and perspectives. We are committed to cultivating an inclusive organization where all Biohubbers feel inspired and know their work makes an important contribution. Therefore, we provide employment opportunities without regard to age, race, color, ancestry, national origin, religion, disability, sex, gender identity or expression, sexual orientation, or any other protected status in accordance with applicable law.

Pursuant to the California Fair Chance Act, we will consider for employment qualified applicants with arrest and conviction records.

Headhunters and recruitment agencies may not submit resumes/CVs through this website or directly to managers. The CZ Biohub Network does not accept unsolicited headhunter and agency resumes. The CZ Biohub Network will not pay fees to any third-party agency or company that does not have a signed agreement with the CZ Biohub Network.

 

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