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Summer Intern - Biohub SF

San Francisco, California, United States

The Chan Zuckerberg Biohub San Francisco (CZ Biohub SF) (https://www.czbiohub.org/sf/) is an independent nonprofit research institute that brings together three powerhouse universities - Stanford, UC Berkeley, and UC San Francisco - into a single collaborative technology and discovery engine. CZ Biohub SF itself supports some of the brightest, boldest engineers, data scientists, and biomedical researchers to investigate the fundamental mechanisms underlying disease and develop new technologies that will lead to actionable diagnostics and effective therapies. We are guided by our values of scholarly excellence; disruptive innovation; hands-on engineering/hacking/building; partnership and collaboration; open communication and respect; inclusiveness; and opportunity for all.

Our Vision

  • We pursue large scientific challenges that cannot be pursued in conventional environments
  • We enable individual investigators to pursue their riskiest and most innovative ideas
  • The technologies developed at CZ Biohub San Francisco facilitate research by scientists and clinicians at our home institutions and beyond

Diversity of thought, ideas, and perspectives are at the heart of CZ Biohub Network and enable disruptive innovation and scholarly excellence. We are committed to cultivating an inclusive organization where all colleagues feel inspired and know their work makes an important contribution.

The Opportunity

CZ Biohub San Francisco is seeking talented undergraduate students to join the organization for the 11-week Summer Internship Program (June 2, 2025 - August 15, 2025). The successful candidates will spend the summer immersed in real-world science with our biomedical researchers, data scientists, and engineers. They will not only gain technical experience working on CZ Biohub SF top line goals, but also soft skills such as communication and critical thinking, as well as the opportunity to network with scientists who provide valuable advice and mentorship.

Possible responsibilities/projects include:

  • Incorporating machine learning techniques to improve Ultrack's performance and reduce the amount of manual fine-tuning required to obtain optimal performance (AI Imaging)
  • Applying machine learning approaches to extract meaningful information from live-cell microscopy zebrafish embryo datasets to make predictions about cell fate and cell behavior (AI Imaging)
  • Generating endogenous labeled cell lines for organelle markers to evaluate changes during infection by herpes viruses (Arias Group)
  • Conducting a direct comparison of the response profiles between Zika and Dengue virus over the first 24 hours of infection in a cell line (Computational Biology)
  • Working on developing new methods and analysis strategies for OrgIP and implementing them in Python (Computational Biology)
  • Contributing to projects for imaging metadata portal (Computational Microscopy)
  • Partnering with mentor/manager to develop experiments related to virology (DeRisi Lab)
  • Characterizing the spatial RNA expression patterns of key signaling molecules at single-cell resolution in developing neuromasts to gain deeper insights (Jacobo Group)
  • Using ML/AI tools for protein modeling and prediction (e.g. Alphafold, diffusion models, etc.) to generate testable hypothesis, followed by wet lab experimentation to validate the findings (Protein Science Group)
  • Learning wet lab experimentation skills such as PCR, cloning, etc. while progressing research on fish live imaging (Royer Group)

You Will 

  • Receive support through a 11-week research experience
  • Receive mentorship to support your personal and professional development
  • Gain and enhance your technical and transferable skills through trainings and seminars
  • Learn how to design, plan, and carry out laboratory and/or computational scientific experiments
  • Present at the end-of-program symposium
  • Build relationships with peers and colleagues

You Have

Program Eligibility –

  • Must be a current undergraduate student (enrolled full time at a college or university both Spring 2025 AND Fall 2025 terms)
  • Must be able to commit to the 11-week Summer Internship Program (June 2, 2025 - August 15, 2025)
  • Must be able to be onsite at the Biohub SF for the entire duration of the program

Compensation

  • $25/per hour
  • CZ Biohub SF- sponsored housing available
  • Relocation reimbursement up to $750

The Chan Zuckerberg Biohub Network requires all employees, regardless of work location or type of role, to provide proof of their initial COVID-19 vaccination by their start date. Those who are unable to get vaccinated because of a disability, or who choose not to be vaccinated due to a sincerely held religious belief, practice, or observance must have an approved exception prior to their start date.

What We Provide

  • Resources to disrupt and innovate at the frontiers of our knowledge of biology and disease
  • A collegial and collaborative environment consisting of diverse expertise
  • Existing collaborations within CZ Biohub: Technology Platforms (Bioengineering, Computational Microscopy, Data Science, Genomic Sequencing, Mass Spectrometry/Proteomics), Infectious Disease, and Quantitative Cell Science
  • Access to collaborators, resources and facilities at our three partner universities (Stanford, UC Berkeley, and UC San Francisco) and at partner organizations in the Bay Area and beyond
  • Competitive compensation and benefits commensurate with the experience

Intern Benefits

  • Hands-on, one-of-a-kind experience
  • Hourly compensation
  • Opportunity to live in CZ Biohub-sponsored housing
  • Invaluable relationships
  • Trainings and seminars
  • Social events/activities

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