Research Scholar, In Vivo Immune Cell Screening (Biohub NY)

The Chan Zuckerberg Biohub New York (CZ Biohub NY) (https://www.czbiohub.org/ny/) is an independent nonprofit research institute that brings together three powerhouse universities - Columbia University, The Rockefeller University, and Yale University - into a single collaborative technology and discovery engine. CZ Biohub NY itself supports some of the brightest, boldest engineers, data scientists, and biomedical researchers to investigate the fundamental mechanisms underlying disease and develop new technologies that will lead to actionable diagnostics and effective therapies. We are guided by our values of scholarly excellence; disruptive innovation; hands-on engineering/hacking/building; partnership and collaboration; open communication and respect; inclusiveness; and opportunity for all.

Our Vision                                                                     

• We pursue large scientific challenges that cannot be pursued in conventional environments
• We enable individual investigators to pursue their riskiest and most innovative ideas
• The technologies developed at CZ Biohub facilitate research by scientists and clinicians at our home institutions and beyond

Diversity of thought, ideas, and perspectives are at the heart of CZ Biohub Network and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution.

The Opportunity

The CZ Biohub NY is looking for a Research Scholar to establish in vivo immune cell screening models to study the role of genetic pertubations on immune cell development and function. You will be establishing both engineered mouse models as well as the engineering and engraftment of hematopoietic stem and progenitor cells into humanized mouse models.

Interested candidates should submit the following documents:

• Cover letter indicating your research experience, interests and career goals
• Full Curriculum Vitae
• Contact information for 3 references

What You'll Do

• Conduct independent and collaborative research
• Design, perform, and analyze experiments
• Establish engineered mouse models and iPSC lines for in vivo gene perturbation
• Establish engraftment protocols in humanized mouse models
• Prepare manuscripts for publication in peer-reviewed journals
• Follow advances in the field through published literature and conferences
• Present your work internally and externally at conferences
• Work closely with fellow team members and external collaborators

What You'll Bring

Essential –

• PhD degree in immunology, developmental biology, molecular biology, genetics, biochemistry, or a related field
• Minimum of 3 years of experience with hands-on animal handling
• Minimum of 2 years of experience working with cloning, molecular biology and gene editing
• The ability to conduct experiments independently
• Demonstrated ability to work in a collaborative environment
• Strong drive to perform cutting-edge research
• Excellent verbal and written communication skills

Nice to have - 

• Hands-on experience in animal surgeries
• Experience with flow cytometry, microscopy and in vivo imaging techniques
• Experience with the production of viral vectors
• Strong knowledge on the existing literature in immunology and genetic engineering
• Experience working with pluripotent stem cells

Compensation

The New York City, NY base pay range for this role is $85,000.00. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process. 

What We Provide

• Resources to disrupt and innovate at the frontiers of our knowledge of biology and disease
• An environment where nothing is considered impossible, where bold and creative thinking are the norm, and where a collaborative culture allows teams of people from multiple disciplines to accomplish more than any single person can achieve alone
• Access to collaborators, resources and facilities at our three partner universities (Columbia University, The Rockefeller University, and Yale University) as well as partner organizations in the CZ Biohub Network and beyond
• Competitive compensation and benefits commensurate with experience

If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.

Benefits

We offer a robust benefits program that enables the important work Biohubbers do every day. Our benefits include healthcare coverage, life and disability insurance, commuter subsidies, family planning services with fertility care, childcare stipend, 401(k) match, flexible time off and a generous parental leave policy. In addition, we honor our commitment to career development and our value of scholarly excellence through regular onsite opportunities to learn from the world's leading scientists.

The CZ Biohub Network is an equal opportunity employer committed to diversity of thought, ideas, and perspectives. We are committed to cultivating an inclusive organization where all Biohubbers feel inspired and know their work makes an important contribution. Therefore, we provide employment opportunities without regard to age, race, color, ancestry, national origin, religion, disability, sex, gender identity or expression, sexual orientation, or any other protected status in accordance with applicable law.

Headhunters and recruitment agencies may not submit resumes/CVs through this Web site or directly to managers. The CZ Biohub Network does not accept unsolicited headhunter and agency resumes. The CZ Biohub Network will not pay fees to any third-party agency or company that does not have a signed agreement with the CZ Biohub Network.