Job Application for Senior Manager, People Partner at Cogent Biosciences

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Who We Are:

Cogent Biosciences is a publicly traded biotechnology company dedicated to developing precision therapies for genetically defined diseases. By leveraging validated biology and a rational drug discovery approach, Cogent aims to create real solutions that address the underlying drivers of disease and offer meaningful hope to patient's.

The company’s lead therapeutic candidate, bezuclastinib, is a highly selective tyrosine kinase inhibitor designed to potently target KIT D816V and other mutations in KIT exon 17. These mutations are known drivers of systemic mastocytosis (SM) and advanced gastrointestinal stromal tumors (GIST) - both serious conditions driven by oncogenic KIT signaling. Bezuclastinib is currently being evaluated in multiple registration-directed trials across Non-Advanced SM (NonAdvSM), Advanced SM (AdvSM), and GIST. In July 2025, Cogent announced that its registration-direct SUMMIT trial in patients with NonAdvSM achieved statistical significance across all primary and key secondary endpoints, and the company is on track to file its first New Drug Application for this patient population by the end of 2025. The company also remains on track to announce top-line results for its APEX trial in patients with AdvSM in the second half of 2025 and for its PEAK trial in patients with GIST by the end of 2025. The company also has an ongoing Phase 1 study of its novel internally discovered FGFR2 inhibitor, and the Cogent Research Team is developing a portfolio of novel targeted therapies to help patients fighting other serious, genetically driven diseases targeting mutations in ErbB2, PI3Kα and KRAS.

Through its commitment to precision medicine and targeted innovation, Cogent Biosciences is working to transform the treatment landscape for patients with serious and underserved diseases. By leveraging validated biology and a rational drug discovery approach, Cogent aims to create real solutions that address the underlying drivers of disease. Our culture of inquisitiveness fuels continuous learning and innovation; we challenge assumptions, ask bold questions, and embrace a mindset of discovery to uncover transformative insights.

The Role:

We are seeking a strategic and experienced Senior Manager, People Partner, to help support our Development and Commercial teams in a fast-paced, innovative-driven environment. This role is instrumental in shaping and executing people strategies that enable high performance, foster a culture of collaboration and scientific excellence, and support the rapid growth of our organization.

Responsibilities:

Build strong relationships with leaders and employees within the Commercial & Development teams, developing a deep understanding of their business, goals, and challenges. Anticipate, assess, and address systemic issues through facilitation, coaching, and counseling.
Guide and coach managers in the performance management process, including setting objectives, providing feedback, conducting performance reviews, and addressing performance issues.
Act as a point of contact for employee relations within Development & Commercial, resolving employee relations issues with a balanced and fair approach.
Partner with leaders to ensure high morale and increase employee engagement.
Collaborate with HR Centers of Excellence (Talent Acquisition, Total Rewards and Operations) to deliver integrated and innovative HR solutions.
Lead or contribute to HR projects that enhance employee experience and operational efficiency.

Qualifications:

Bachelor’s degree or HR certification (e.g., SHRM-SCP, SPHR) preferred.
7+ years of progressive HR experience, with at least 3 years in a business partner role.
Experience supporting Development and/or Commercial teams in the life sciences industry preferred.
Excellent interpersonal, communication, and coaching skills.
Proven ability to influence and build relationships across all levels of the organization.
Comfortable navigating ambiguity and driving change in a dynamic environment.

Salary Range:

$160k - $180k USD

Target Bonus: 15%

Exact compensation will vary based on skills, experience, and location.

Our Locations

Waltham, MA: Our Boston office includes an open office layout that has recently undergone a makeover designed for collaboration and giving our employees the best work place possible. Free access is provided for both on-site parking and gym facilities in the building.

Boulder, CO: We have just moved into our new state-of-the art Research Facility in the fast-growing biopharmaceutical hub in the greater Denver/Boulder corridor. Our CEO is based full-time in this location and we are proud to call this the home of Cogent’s discovery research organization.

Our Offer To You

To attract the very best talent, we offer a generous benefits package that includes competitive pay, performance-based bonus, stock options, insurance coverage (health, dental, life, and disability), competitive time-off, a 401(k) plan, and commuter/parking benefits.

We are proud to be an Equal Opportunity Employer. Our goal is to have a diverse workforce. We do not discriminate on the basis of race, age, color, religion, national origin, gender, sexual orientation, gender identity or expression, veteran status or disability, or any other status protected under federal, state, or local law. All employment is decided on the basis of qualifications, merit, and business need.

Senior Manager, People Partner

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