Director, Health Economics and Outcomes Research (HEOR) – Oncology (Europe)

Corcept is leading the way in the research and development of cortisol modulators, molecules that regulate cortisol activity at the glucocorticoid receptor (GR). To date, we have discovered more than 1,000 selective proprietary cortisol modulators.

In 2012, we received FDA approval of Korlym® (mifepristone), the first approved treatment for hypercortisolism (Cushing’s syndrome).

Today, our team and collaborators continue to unlock the possibilities of cortisol modulation as a way to treat serious diseases. With more than 30 ongoing studies across a wide range of disease areas, including endocrinology, oncology, metabolism, and neurology, we remain dedicated to advancing the possibilities of cortisol modulation.

What began as a ripple of scientific truth is now poised to unleash a sea change of discovery representing a fundamental shift in the way we understand and treat disease.

We are seeking a highly skilled and experienced Director of Health Economics and Outcomes Research (HEOR) with a strong focus on Oncology to join our team. The ideal candidate will play an integral role in the launch and commercialization activities of our oncology portfolio globally. This role will report to Senior Director of HEOR, located in Redwood Shores, California. 

This position involves working cross-functionally with Medical Affairs, Market Access, and Clinical Development. This role offers the opportunity to drive scientific leadership and innovation, developing new methodologies and evidence strategies to enhance the understanding of the value of oncology treatments and advance the organization’s mission of delivering life-changing therapies to patients worldwide. 

Responsibilities:

• Spearhead the development and strategic implementation of Value Dossiers (AMCP & global value dossiers) for oncology products, ensuring alignment with clinical, scientific, and economic data to support market access and reimbursement negotiations in the US and global markets
• Lead and oversee the design and execution of systematic literature reviews to generate high-quality evidence that informs health economic models, HTA submissions, and reimbursement strategies. Establish rigorous methodologies for literature search, inclusion/exclusion criteria, and data extraction, ensuring robust evidence synthesis to support strategic decision-making
• Cost-Effectiveness and Budget Impact Models: Develop, adapt, and oversee the creation of cost-effectiveness models and budget impact models for oncology therapies. Collaborate with internal stakeholders to ensure alignment with global pricing and market access strategies
• Indirect Treatment Comparisons (ITC): Manage and lead the execution of indirect treatment comparison studies to assess the relative efficacy of oncology therapies in comparison to competing products or alternative treatment options
• Real-World Evidence (RWE) and Observational Studies: Design, execute, and oversee real-world observational studies (e.g., registries, retrospective studies) to assess the long-term outcomes, effectiveness, and safety of oncology therapies in routine clinical practice
• Health Technology Assessment (HTA) Dossier Development: Support the preparation of HTA submissions for oncology products, ensuring all the evidence needs are adequately captured for the key EU markets. Collaborate with cross-functional teams to ensure optimal evidence generation for reimbursement
• Drive innovation within HEOR by identifying emerging methodologies and best practices in health economics, epidemiology, and outcomes research. Lead the development of novel models, frameworks, and tools that enhance the understanding of oncology therapy value. Serve as a key scientific leader, representing the company in external engagements, conferences, and industry forums
• Act as a strategic partner to clinical development, regulatory affairs, commercial, and medical affairs teams, ensuring HEOR insights are seamlessly integrated into global and local market access strategies
• Develop and present HEOR evidence to internal executives, external stakeholders, payers, and HTA bodies to drive alignment on the value proposition of oncology therapies. Establish and maintain strong relationships with key decision-makers in the healthcare ecosystem
• Demonstrate strong leadership in cross-functional and cross-regional teams, fostering a high-performance culture and influencing senior stakeholders with data-driven insights
• Uphold Corcept’s Key Principles by driving collaboration, embracing possibilities, following the data, and leading by doing, ensuring all initiatives align with the Company’s ethics and patient-first principles

Preferred Skills, Qualifications and Technical Proficiencies:

• Proficiency in advanced statistical and modeling techniques for economic evaluation (e.g., Markov models, decision trees, cohort simulations)
• In-depth knowledge and ability to apply knowledge of US and global healthcare systems, global HTA requirements, and clinical development, to identify evidence gaps and formulate evidence generation and communication strategies 
• Expertise in the preparation and delivery of high-quality, evidence-based health economic reports and presentations to stakeholders at various levels  
• Generate peer-reviewed publications to communicate study findings in scientific channels in alignment with the product publication strategy and the overall HEOR evidence generation strategy 
• Strong project management skills, with the ability to manage multiple priorities and deadlines

Preferred Education and Experience:

• Advanced degree (PhD, MSc, or equivalent) in health economics, public health, health policy, statistics, or a related field. A focus on oncology is highly desirable
• At least 5-10 years of experience in HEOR, with a strong background in oncology
• Proven experience developing cost-effectiveness models, budget impact models, and global value dossiers for oncology products
• Demonstrated expertise in indirect treatment comparisons, real-world evidence generation, and observational study designs (e.g., registries)
• Proficiency in English is required 
• 10% with travel as required 

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The pay range that the Company reasonably expects to pay for this position is £130,000 – £150,000 per annum; the pay ultimately offered may vary based on legitimate considerations, including geographic location, job-related knowledge, skills, experience, and education.

 Applicants must be currently authorized to work in the United States on a full-time basis.

For information on how Corcept collects, uses, discloses, protects, and otherwise processes personal information and an explanation of the rights and choices available to you with respect to your personal information, please refer to our Privacy Notice link. 

Corcept appreciates the commitment and hard work of all our team members as we strive to discover and develop novel treatments for patients with serious unmet medical needs.

 Please visit our website at: https://www.corcept.com/

Corcept is an Equal Opportunity Employer

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