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Scientist - Electron Microscopy Technology Platform

Redwood City, CA

To develop a dynamic, integrated view of biological systems in health and disease, the Chan Zuckerberg Institute for Advanced Biological Imaging (CZ Imaging Institute) aims to push forward the development and application of new imaging technologies over the next 10 to 15 years. CZ Imaging Institute researchers will collaboratively develop breakthrough biological imaging systems centered around grand challenges that push the boundaries of what we can see and measure to obtain deep insights into the architecture of complex biological systems at the molecular level.

As an extension of the Chan Zuckerberg Initiative’s Imaging program, the CZ Imaging Institute (https://czii.org/) will create breakthrough technologies — hardware, software, biological probes, data, and platforms — that will be made available to the scientific community and adopted worldwide through a combination of direct access to the Institute, open sharing of advances, and commercial partnerships.

The Opportunity 

We are seeking an experienced an experienced Scientist, Electron Microscopy Technology Platform (TP01), to be responsible for the automation and optimization of a cryo-electron tomography (cryoET) data collection pipeline. This position offers the opportunity to work at the forefront of cryo-electron microscopy technology, contributing to groundbreaking research and pushing the boundaries of what is possible in structural biology and molecular imaging.

What You’ll Do

  • Maintain and curate software applications for the current cryoET data collection pipeline, which includes cryo light microscopes, focused ion beam scanning electron microscopes, and cryo transmission electron microscopes.
  • Develop and adapt software solutions to improve throughput and overall integration of the data collection workflow.
  • Coordinate closely with researchers and technology developers to understand their imaging needs and devise tailored solutions to meet those requirements.
  • Stay up-to-date with the latest technologies and advancements in the field of electron microscopy, and integrate these innovations into the facility’s workflows.

What You’ll Bring

Essential –

  • PhD in biophysics, structural biology, or a closely related field
  • 3+ years of experience developing software applications for microscopy, particularly in the areas of instrument control and data acquisition (for electron microscopes)
  • Strong knowledge of electron microscopy techniques, equipment, and data processing workflows
  • Excellent software development skills, preferably in Python
  • Proven track record of working effectively both independently and as part of a collaborative team
  • Excellent problem-solving, analytical, and organizational abilities

Nice to have - 

  • Prior experience in preparing lamella on vitrified biological samples
  • Familiarity with Thermo Fisher Scientific FIB-SEMs and Transmission Electron Microscopes (TEMs)
  • Experience implementing automation in lamella-preparation workflows
  • Master's degree in a relevant field
  • Publication record demonstrating expertise in CryoEM techniques

The Chan Zuckerberg Biohub Network requires all employees, regardless of work location or type of role, to provide proof of their initial COVID-19 vaccination by their start date. Those who are unable to get vaccinated because of a disability, or who choose not to be vaccinated due to a sincerely held religious belief, practice, or observance must have an approved exception prior to their start date.

Compensation

  • Salary Range = $92,000 - $137,000

New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. To determine starting pay, we consider multiple job-related factors including a candidate’s skills, education and experience, market demand, business needs, and internal parity. We may also adjust this range in the future based on market data. Your recruiter can share more about the specific pay range during the hiring process.

What We Provide

  • Resources to collaboratively develop breakthrough biological imaging systems that push the boundaries of what we can see and measure
  • An environment where nothing is considered impossible, where bold and creative thinking are the norm, and where a collaborative culture allows teams of people from multiple disciplines to accomplish more than any single person can achieve alone
  • Access to collaborators and resources at partner organizations in the CZ Biohub Network and beyond
  • Competitive compensation and benefits commensurate with experience

Benefits

We offer a robust benefits program that enables the important work employees do everyday. Our benefits include healthcare coverage, life and disability insurance, commuter subsidies, family planning services with fertility care, childcare stipend, 401(k) match, flexible time off and a generous parental leave policy. In addition, we honor our commitment to career development and our value of scholarly excellence through regular onsite opportunities to learn from the world's leading scientists.

The CZ Biohub Network is an equal opportunity employer committed to diversity of thought, ideas and perspectives. We are committed to cultivating an inclusive organization where all employees feel inspired and know their work makes an important contribution. Therefore, we provide employment opportunities without regard to age, race, color, ancestry, national origin, religion, disability, sex, gender identity or expression, sexual orientation, or any other protected status in accordance with applicable law.

Pursuant to the California Fair Chance Act, we will consider for employment qualified applicants with arrest and conviction records.

Headhunters and recruitment agencies may not submit resumes/CVs through this website or directly to managers. The CZ Biohub Network does not accept unsolicited headhunter and agency resumes. The CZ Biohub Network will not pay fees to any third-party agency or company that does not have a signed agreement with the CZ Biohub Network.

 

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