Senior Research Associate

Job Title: Senior Research Associate
Location: Watertown, MA (onsite)

The Role

We are seeking a Senior Research Associate to join our collaborative research team. This role is ideal for someone who thrives in an agile research environment, enjoys hands-on experimental work, and is motivated by the opportunity to manage efficient processes that support a diverse set of scientific and technological directions. 

Key Responsibilities

• Cell Culture Leadership: Maintain, passage, bank, and distribute a variety of mammalian cell lines to support R&D programs.
• Facility & Operations: Ensure smooth day-to-day operation of the cell culture facility, including equipment care and restocking.
• Sample & Inventory Management: Work with Operations to maintain robust tracking systems for cell lines, reagents, and consumables.
• Assay Development & Execution: Perform immunology functional assays and cell line validation experiments.
• Cell Line Engineering: Support CRISPR-based editing, transgene overexpression, and related projects to generate new cell line models.
• Protein Production Support: Contribute to upstream protein expression workflows in mammalian cells.
• Molecular Biology Support: Provide occasional assistance with molecular cloning and bacterial culture to support project needs.

Qualifications

• B.S. or M.S. in Cell Biology, Immunology, Molecular Biology, Biotechnology, or related field, and 2+ years of prior industry experience. 
• 3–5+ years of hands-on experience in mammalian cell culture -  proficiency with sterile technique and varied cell lines and growth formats (adherent and suspension).
• Experienced in transfection methods, immunocytochemistry, and fundamental imaging techniques. 
• Adept at sample tracking, inventory, and note-taking using ELN/LIMS systems.
• Experience with immunology assays and/or functional cell-based assays preferred.
• Experience with 3-D models (spheroids, organoids) is a plus.

Skills & Attributes:

• Strong organizational and record-keeping skills with attention to detail.
• Ability to manage multiple tasks that intersect R&D teams.
• Excellent communication and collaboration skills within cross-functional teams.
• Self-motivated, proactive, and eager to learn new techniques.
• Able to work flexible hours, including periodic weekend hours.

Company Benefits: Health, vision, life, dental insurance and 401K plan.

If you don't meet all of the requirements listed here, we still encourage you to apply or reach out to us. No job description is perfect – we may find an even more suitable opportunity that is a better fit for you.