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Scientist I, Protein Analytics (Developability)

Waltham, Massachusetts, United States

Scientist I, Protein Analytics (Developability)

Dragonfly Therapeutics is seeking an exceptional Scientist to join our Protein Analytics team. In this critical role, you will guide lead candidate identification and developability assessments of next-generation biologics, including multispecific molecules, cytokines, and novel agents targeting diseases such as cancer and autoimmune diseases (AID). By interrogating molecular properties, your work will forge the lifecycle of our therapeutic candidates, enabling their successful translation into the clinic and beyond.

Why Join Dragonfly?

At Dragonfly, we thrive in a fast-paced, entrepreneurial environment, tackling some of the most exciting challenges across diverse disease indications. Join us and become part of a team that is redefining what's possible in science.

  • Work on innovative, clinically impactful therapies that target unmet medical needs in oncology, autoimmune diseases and beyond.
  • Be part of a collaborative, high-energy team dedicated to pioneering novel biologic classes.
  • Shape the therapeutic pipeline by driving decisions from early discovery to clinical development.
  • Grow your career in a supportive environment that values scientific rigor, creativity, and cross-functional collaboration.

Dragonfly Therapeutics offers a vibrant culture where innovation meets impact. If you're excited to transform science into therapies that change lives, we want to hear from you!

Key Responsibilities (including but not limited to): 

  • Lead biophysical and biochemical characterization to guide candidate selection and support the development of groundbreaking biologics
  • Perform and interpret advanced developability assessments, encompassing stability, aggregation, and manufacturability analyses
  • Collaborate cross-functionally with research, CMC, and clinical teams to ensure alignment in therapeutic development strategies
  • Maintain detailed, high-quality documentation in electronic laboratory notebooks, ensuring compliance and traceability

Qualifications: 

  • BS/MS with 6+ years relevant industrial experience in biotherapeutic characterization and development
  • Strong hands-on experience in protein characterization techniques such as SEC, HIC, IEX, CE-SDS, DSC, and cIEF
  • The candidate should be self-motivated, accountable, inquisitive, and have excellent organization and communication skill

About Dragonfly

Dragonfly Therapeutics is a clinical-stage biopharmaceutical company committed to discovering, developing and commercializing therapies that use its novel multispecific antibody technology to harness the body's immune system to bring breakthrough treatments to patients. In addition to its wholly owned clinical assets, Dragonfly has a deep pipeline of wholly owned preclinical candidates discovered using its proprietary platform, as well as productive collaborations with Merck, AbbVie, Gilead and Bristol Myers Squibb in a broad range of disease areas. 

Our mission is to revolutionize disease treatment by inventing natural killer cell-based therapies for vastly improved patient outcomes. We believe in a small team with a big impact.

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