Senior Enterprise Program Manager

GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com.

Summary

The Senior Program Manager is responsible for planning, executing, and delivering large, cross-functional programs that align with the company’s strategic goals. This role ensures that multiple related projects stay on track, achieve broader business objectives, and drive organizational vision. The Senior Program Manager serves as a central point of alignment across departments, managing resources, timelines, and risk to deliver program-wide success.

Job Responsibilities

• Program Leadership: Oversee the entire program lifecycle, from inception to completion, ensuring alignment with strategic objectives and company vision.
• Cross-Functional Collaboration: Act as the primary liaison across departments to ensure that all stakeholders are aligned and working toward common goals.
• Alignment and Planning: Develop program strategies in collaboration with senior leadership and define a roadmap for success with clear milestones.
• Risk and Issue Mitigation: Proactively identify and mitigate risks to ensure seamless progress, addressing roadblocks before they impact program outcomes.
• Resource Management: Coordinate resource allocation across projects to maximize efficiency and maintain balance across the program.
• Stakeholder Communication: Keep all relevant stakeholders informed of program progress, changes, and risks through regular updates and communication.
• Continuous Improvement: Drive process improvements across program operations, ensuring that best practices are followed and lessons learned are applied.

People Manager

• No

Education, Experience, and Skills

• Extensive experience (7+ years) in program and project management, with a focus on cross-functional collaboration.
• Excellent communication, organizational, and leadership skills.
• Demonstrated experience in implementing project management software.
• Exceptional verbal and written communication including an ability to communicate effectively at an executive level
• Ability to work collaboratively across distributed workforce
• Possesses significant practical experience in project management (project planning, resource planning, issue management, risk management, change management, communication planning)
• Excellent organizational skills and capable of setting priorities and a demonstrated ability to deliver projects on time, on budget and within scope
• Proven accomplishment as a driver of multiple projects running concurrently
• Exhibit good judgment skills on when to seek guidance and when to escalate risks and issues
• Experience in the healthcare, biotech, or genomics industry is a plus

Certificates, Licenses, Registrations

• Certified Project Management Professional (PMP) with a proven track record of success.

Physical Demands

 The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

 While performing the duties of this Job, the employee is frequently required to stand; sit and use hands to finger, handle, or feel.  The employee is occasionally required to walk; reach with hands and arms; stoop, kneel, crouch, or crawl and talk or hear. The employee must occasionally lift and/or move up to 10 pounds.  Specific vision abilities required by this job include color vision.

Work Environment

• Work is primarily performed in a home office setting or telework space with a typical climate-controlled environment.

Acknowledgements

The above job description is not intended to be an all-inclusive list of duties and standards of the position.  Incumbents will follow any other instructions, and perform any other related duties, as assigned by their supervisor.   

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Science - Minded, Patient - Focused. 

At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.

Experts in what matters most. 

With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.

SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES.

From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:

TECHNICAL EXPERTISE

• High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.
• Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.

CLINICAL EXPERTISE

• Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.
• Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.
• Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.

Learn more About Us here.

Our Culture

At GeneDx, we are dedicated to cultivating an environment where creativity and innovation thrive. We believe in the power of community and collaboration, where diverse perspectives are embraced, and every voice contributes to our shared success. Our team is a vibrant mix of professionals who challenge and support each other in equal measure, fostering growth both personally and professionally. When you join us, you're not just taking on a job—you're joining a movement. A movement that champions curiosity, embraces change, and believes in making an impact, one patient at a time. Cultural principles we live by:  

• Be bold in our vision & brave in our execution. 
• Communicate directly, with empathy. 
• Do what we say we're going to do.  
• Be adaptable to change.  
• Operate with a bias for action.    

Benefits include:

• Paid Time Off (PTO)
• Health, Dental, Vision and Life insurance
• 401k Retirement Savings Plan
• Employee Discounts
• Voluntary benefits

GeneDx is an Equal Opportunity Employer.

All privacy policy information can be found here.