Back to jobs
New

Vice President, Strategic Sourcing & Procurement

Bedford, Massachusetts, United States

About Stoke:

Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke’s proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke’s first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke’s initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke’s proprietary approach. Stoke is headquartered in Bedford, Massachusetts. For more information, visit https://www.stoketherapeutics.com/

Position Purpose:

We are seeking a Vice President, Strategic Sourcing and Procurement to serve as an enterprise leader responsible for designing, scaling, and overseeing Stoke’s strategic sourcing, procurement, and supplier governance capabilities as the company expands its operations, increases headcount and prepares for potential commercialization. Reporting to the Chief Financial Officer, this executive will build a high-impact function that enables disciplined spend management, enterprise risk mitigation, operational excellence, and strong partnerships across the entire company. The VP will act as a strategic advisor to senior leadership, establish procurement governance and decision-making frameworks, lead complex supplier and contract negotiations, and ensure Stoke has the vendor infrastructure, controls, and commercial readiness required to support proper financial controls during rapid growth.

Key Responsibilities:

  • Establish and lead the enterprise strategic sourcing and procurement function, including the operating model, governance structure, policies, systems, controls, and performance expectations required to support a growing clinical-stage and potentially commercial biotechnology company
  • Serve as a strategic partner to the executive team and functional leaders, advising on sourcing strategy, supplier risk, contracting priorities, spend optimization, and vendor capabilities needed to advance corporate objectives
  • Lead complex, high-value RFPs/RFQs/RFIs and supplier selection processes in partnership with business stakeholders, legal, finance, quality, and compliance
  • Oversee negotiation strategy for material agreements, ensuring favorable commercial terms, appropriate risk allocation, scalability, and alignment with business priorities
  • Build and manage a strategic supplier relationship management program, including executive-level vendor engagement, performance scorecards, issue escalation, corrective action planning, and lifecycle governance
  • Lead enterprise spend visibility and analytics, identifying opportunities for cost avoidance, savings, process efficiency, consolidation, risk mitigation, and improved forecasting
  • Partner with Finance and functional leaders to strengthen budget discipline, purchase-to-pay processes, contract lifecycle management, and alignment between sourcing decisions and financial planning
  • Establish key procurement metrics and executive reporting to monitor performance, compliance, value creation, supplier concentration, risk, and continuous improvement opportunities
  • Ensure procurement practices comply with applicable laws, regulations, company policies, quality expectations, and internal control requirements
  • Build, mentor, and scale a high-performing procurement team, fostering business partnership, accountability, continuous improvement, and a service-oriented culture
  • Partner with IT team to implement financial systems that enable better financial controls and spend management
  • Maintain external awareness of market trends, supplier dynamics, technology innovation, and procurement best practices relevant to biotechnology, clinical development, and commercialization

Required Skills & Experience:

  • Minimum of 15 years of relevant strategic sourcing, procurement, vendor management, finance, or operations experience, including significant leadership experience in the pharmaceutical, biotechnology, or life sciences industry
  • Demonstrated success building and scaling an enterprise procurement function in a high-growth clinical development environment; commercialization readiness or commercial-stage experience required
  • Enabled companywide savings through outsourcing-led initiatives over both short- and long-term periods
  • Bachelor’s degree required; advanced degree or relevant professional certification preferred
  • Executive-level understanding of drug development, clinical trials, CRO oversight, clinical supply chain, manufacturing, quality, regulatory expectations, and commercial readiness considerations
  • Proven ability to influence senior leaders, lead cross-functional decision-making, and balance enterprise priorities across cost, quality, speed, risk, innovation, and compliance
  • Extensive experience leading complex supplier negotiations and advising on material contract terms, business implications, risk allocation, service levels, performance obligations, and governance structures
  • Strong financial and analytical acumen, including spend analysis, value creation, budgeting, forecasting, KPI development, and executive-level reporting
  • Experience selecting, implementing, or optimizing procurement processes, systems, contract lifecycle tools, purchase-to-pay workflows, and internal control frameworks
  • Track record of building and leading high-performing teams, developing talent, and creating scalable operating models in dynamic, fast-paced environments
  • Excellent executive communication skills, including the ability to distill complex issues, present recommendations, and drive alignment with senior management and cross-functional stakeholders

Location(s):

Stoke is located in Bedford, MA, and will be moving to a new location in Waltham, MA by the end of 2026. This position is a hybrid position, currently based in Bedford and will later be based in Waltham.

Travel:

This position will require approximately 10% travel.

Compensation & Benefits:

At Stoke Therapeutics, we are committed to offering a comprehensive, competitive and thoughtfully designed total rewards program.

The anticipated salary range for this role is $227,000 - $345,000. The final offer will be determined based on a variety of factors, including role scope, experience and qualifications, education, market benchmarks, internal equity, and geographic location. In addition to base salary, Stoke offers an annual bonus and equity participation.

Our benefits package includes medical, dental and vision insurance; life, long- and short-term disability insurance; paid parental leave; a 401K plan with company match, unlimited vacation time, tuition assistance and participation in our Employee Stock Purchase Program (ESPP).

Culture & Values:

At Stoke, we believe that innovation, the ability to successfully advance our ground-breaking science and having fun as a team are enhanced by being together in person, at least periodically. We allow for flexibility in work arrangements that balance individual’s needs and preferences with the needs of our business and our desire to foster a culture of collaboration and innovation.

Our values guide our work to deliver meaningful medicines for people who need them. We are committed to being true to ourselves, to our colleagues, and to the people with severe diseases who are counting on us. We embrace diversity within a unique culture that is defined by our values. Our employee-led Diversity, Inclusion, and Belonging (DIB) Committee underscores the importance of DIB to who we are and what we do. 

Interested candidates: Please visit Stoke’s website to learn more and apply directly to the position listed on our Career Center:

https://www.stoketherapeutics.com/careers/

For more information, visit https://www.stoketherapeutics.com/.

All applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, physical or mental disability or protected veteran status.

Stoke participates in E-Verify.

Apply for this job

*

indicates a required field

Resume/CV*

Accepted file types: pdf, doc, docx, txt, rtf

Cover Letter

Accepted file types: pdf, doc, docx, txt, rtf

Education

Select...
Select...
Select...
Select...
Select...
Select...
Select...
Select...
Select...

I certify that I have read and understand the applicant instructions included with this application and that the answers given by me to the foregoing questions and statements made by me are complete and true to the best of my knowledge and belief.


I certify that I understand that Stoke Therapeutics participates in E-Verify and will provide the federal government with my Form I-9 information to confirm that I am authorized to work in the United States once I have accepted a job offer and completed the Form I-9.


I understand that any false information, omissions or misrepresentations of facts called for in this application, whether on this document or not, may result in rejection of my application or discharge at any time during my employment. 


I understand that this application form is intended for use in evaluating my qualifications for employment and that this application is not an offer of employment. I further understand that if hired, my employment will be considered "at-will" and that my employment may be terminated for any reason, with or without cause or notice, at any time by me or the Company and that this application is not intended to constitute a contract of continued employment.

Select...

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in Stoke Therapeutics’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

Select...
Select...
Race & Ethnicity Definitions

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Select...

Voluntary Self-Identification of Disability

Form CC-305
Page 1 of 1
OMB Control Number 1250-0005
Expires 07/31/2029

Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

  • Alcohol or other substance use disorder (not currently using drugs illegally)
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
  • Blind or low vision
  • Cancer (past or present)
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or serious difficulty hearing
  • Diabetes
  • Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
  • Epilepsy or other seizure disorder
  • Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
  • Intellectual or developmental disability
  • Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
  • Missing limbs or partially missing limbs
  • Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
  • Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
  • Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
  • Partial or complete paralysis (any cause)
  • Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
  • Short stature (dwarfism)
  • Traumatic brain injury
Select...

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.