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Associate Director, Medical Affairs Operations

Boston, MA

The Organization

What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible. 

Our Endosomal Escape Vehicle (EEV™)-therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues, resulting in an improved therapeutic index. Through this proprietary, versatile and modular approach, Entrada is advancing a robust development portfolio of RNA- and protein-based programs for the potential treatment of neuromuscular and ocular diseases, among others.

Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne who are exon 44, 45, 50 and 51 skipping amenable. Entrada has partnered to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1.

We are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.

The Perfect Addition to Our Team

You want to join a high growth organization where your expertise directly shapes congress strategy and execution as well as building medical affairs operations capability. You thrive in a collaborative and fast paced environment that requires strategic thinking, strong project management, and attention to detail.  

The Opportunity

The Medical Affairs Operations Lead is a newly created position and will report the SVP of Medical Affairs. The individual will be responsible for building and executing the operational infrastructure required to support Entrada’s growing Medical Affairs function across neuromuscular and other therapeutic programs. This role will serve as the tactical engine for Medical Affairs—driving operational excellence, cross-functional alignment, compliant execution, and efficient resource management. The ideal candidate brings deep experience in medical affairs operations within high-growth biotech and thrives in an environment where processes, systems, and standards are being built for the first time. 

Responsibilities

Medical Congress Operations (Global & Regional) 

  • Lead end-to-end planning and execution of Medical Affairs activities at scientific and medical congresses (e.g., AAN, MDA, WMS).
  • Manage scientific booth operations, including vendor oversight, logistics, materials development, metrics capture, and post-congress reporting. 
  • Develop and steward a comprehensive annual congress strategy and calendar. 

Medical Affairs Team Operations & Governance 

  • Plan, execute, and optimize Medical Affairs team meetings and cross-functional congress planning meetings 
  • Maintain the Medical Affairs annual strategic plan, key deliverable tracker, and operational KPIs. 

Budget Management & Financial Operations 

  • Own Medical Affairs budget tracking, forecasting, and monthly accruals in partnership with Finance. 
  • Manage PO (Purchase Order) creation, approval workflows, vendor contracts, and invoice reconciliation. 
  • Develop and implement budget visibility tools (dashboards, trackers) for leadership. 
  • Review vendor proposals, SOWs, and contracts for operational feasibility and cost efficiency. 

Grants, Funding & External Support Programs 

  • Manage the Independent Medical Education (IME) grant process, ensuring compliant review, approval, and documentation in accordance with Entrada policies and OIG/PhRMA guidance. 
  • Oversee investigator-initiated studies (IIS) and externally sponsored research (ESR) operations, including intake, feasibility review coordination, contract routing, and milestone tracking. 
  • Align with Legal, Compliance, and Clinical Operations to ensure appropriate scientific rationale, fair-market value (FMV) assessments, and compliant disbursement of funds. 
  • Maintain a centralized database of all MA-supported grants and funding programs with performance metrics. 

The Necessities

At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

  • Humanity - We genuinely care about patients and about one another.
  • Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
  • Creativity - We are creative problem solvers.
  • Collaboration - We are more than the sum of our parts.
  • Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

  • Bachelor’s degree in a scientific field with a successful track record working in the pharmaceutical or biotech industries for 5 + years.  
  • 5+ years of experience in Medical Affairs Operations within biotech/pharma; rare disease or RNA therapeutics experience a plus. 
  • Exceptional project management, budgeting, and vendor management skills. 
  • Ability to work cross-functionally, influence without authority, and lead through ambiguity. 
  • Highly organized, detail-oriented, and comfortable operating at both strategic and tactical levels. 
  • Ability to travel (US and International) approximately 30% of time.
  • This role follows a hybrid working model, with office attendance 2-3 days per week minimum at the Entrada Therapeutics Headquarters in Boston, MA. 

What We Offer: Meaningful Work, Fair Rewards, and Real Support

At Entrada Therapeutics, we understand that compensation and total rewards are a major consideration when exploring a new opportunity. We believe in transparency and equity and are committed to sharing salary ranges for every position, along with insight into our compensation philosophy, in accordance with certain state requirements in the United States and fostering a fair and open environment at the onset.

But we also know it is more than just pay. When you join Entrada, you’ll be part of a mission-driven team with access to comprehensive health, dental and vision coverage; life and disability insurance; with a 401(k) match. We pride ourselves on offering competitive benefits that empower our employees and reflect the value of their contributions – offering paid, gender-inclusive parental leave, holistic support for your health and well-being, education reimbursement, discretionary time off and commuting benefits aligned to your working model. If you find yourself working from our office in Boston’s Seaport District, this puts you steps away from some of the best the city has to offer.

“Our approach to compensation is grounded in transparency, equity and performance for the unique contributions each person brings. At Entrada, we know that meaningful work deserves meaningful reward — and we view compensation as one way we show appreciation for the collaboration, curiosity and commitment that drive our mission forward.”

— Kerry Robert, SVP of People

The salary for this opportunity ranges from $182,000 – $214,000. The final base compensation offered will depend on several considerations which include but may not be limited to a candidate’s skills, competencies, experience and other job-related factors permitted by law. The final salary offered may fall outside of this range.

Equal Opportunity Employer

Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law. 

Third Party Staffing Agencies

Entrada does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Entrada from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Entrada and do not obligate Entrada to pay fees if we hire from those resumes.

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