Senior Genomic Data Engineer

Harbinger Health is pioneering the detection of early cancer and enabling foundationally new approaches to cancer screening, diagnosis, and management. Incubated within Flagship Pioneering for three years before launching in 2021, Harbinger combines advances in artificial intelligence with proprietary insights into the biology of early cancer cell formation to identify cancer before it is visible or symptomatic with the aim of developing low-cost, multi-cancer blood tests.

At Harbinger, we intend to lead in shaping this future – creating a proactive paradigm so that people can live cancer-free for longer, adding years to life and life to years. We envision a future where, instead of keeping cancer from spreading, it could be kept from forming, making a cancer diagnosis a routine health problem to be addressed rather than a life-altering event to be feared with profound implications for people, healthcare systems and societies.

Our answer starts with proprietary solutions we are developing with our platform technology.  By making cancer screening accessible on a global scale, Harbinger Health has the potential to fundamentally change cancer care, for everyone.

Our lifesaving work is grounded by our principles of rigor and transparency, constructive engagement, inclusiveness, accountability and quality, and a strong commitment to our customers, patients, and each other.  These values drive our decisions and actions. We are a highly dynamic, entrepreneurial, and innovation-driven organization seeking collaborative, passionate, and dedicated people to join our team.

Job Description – Senior Genomic Data Engineer

Position Summary 

As a Senior Genomic Data Engineer at Harbinger Health, you will develop and refine our bioinformatics pipeline. This work is essential for the automation and processing of patient sample data. Your contributions will include implementing and sustaining sophisticated engineering solutions and ensuring that these systems undergo rigorous testing and comprehensive documentation to meet necessary clinical standards. This role requires a background in software development, expertise working with genomic data, and an adeptness for cloud-based computing solutions. This role is vital in supporting Harbinger’s mission through innovation in bioinformatics.

Responsibilities:

• Develop and maintain Harbinger's bioinformatics pipeline, ensuring its integrity and efficiency.
• Transition research-grade algorithms to production-level software, incorporating best practices.
• Execute comprehensive testing at unit, functional, and integration levels before production deployment.
• Collaborate with quality control and regulatory teams to create thorough software documentation.
• Analyze and interpret complex genomics data, focusing on bisulfite sequencing.
• Employ rigorous statistical methods to extract and summarize biological insights from high-dimensional data sets.
• Design experiments in conjunction with computational and experimental scientists.
• Present findings clearly and effectively to stakeholders.

Basic Qualifications:

• Ph.D., M.S., or B.S. in computer science, bioinformatics, computational biology, biostatistics, or a related quantitative field is highly desirable.
• At least 3 years of industry experience in a computational role working with genomic data.
• At least 5 years of extensive programming in Python, with a portfolio of production-level software on GitHub or similar platforms.
• Experience in software documentation within CLIA/CAP/FDA regulated environments.
• Experience in building databases and data lake solutions for NGS data.
• Proficiency in workflow languages such as Nextflow.
• Comfortable operating in a Linux environment and knowledgeable in AWS cloud computing.
• Demonstrated experience in the analysis of complex biological datasets, evidenced by publications, presentations, and/or patents.
• Exceptional communication and presentation abilities, capable of translating complex data into actionable insights and communicating to wide audiences.

Preferred Qualifications:

• Expertise in experimental design, data processing, statistical analysis, and bioinformatics reporting of various NGS and microarray platforms.
• Proven ability to excel in a fast-paced and dynamic environment, with a strong orientation towards teamwork.

Harbinger Health is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies: Harbinger Health does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Harbinger Health or its employees is strictly prohibited unless contacted directly by Harbinger Health’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Harbinger Health, and Harbinger Health will not owe any referral or other fees with respect thereto.