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Clinical Research Operations Director

Plymouth, MA

At Headlands Research, we are dedicated to enhancing clinical trial delivery within our communities. As a leading network of advanced clinical trial sites, we leverage cutting-edge technology and exceptional support services to broaden outreach and participation. Founded in 2018, our rapidly growing company currently operates 20+ sites across the US and Canada, with plans for further expansion.

 

Site Director – Transformational Clinical Research Leader

 

The Opportunity

Are you a seasoned clinical research leader ready to turn challenge into momentum? We are seeking a bold, hands-on Site Director to step into a clinical research site with untapped potential and lead its transformation into a high-performing, patient-centered operation.

This is not a maintenance role—it’s a build, elevate, and lead opportunity. You will have the autonomy, visibility, and support to implement best-in-class operational processes, mentor and inspire your team, and directly impact enrollment performance, data quality, and financial outcomes. If you thrive in environments where your leadership truly matters, this role offers the chance to leave a lasting mark.

What You’ll Do

As Site Director, you will serve as the operational and cultural heartbeat of the site—balancing strategy with execution and leadership with accountability.

 

Lead & Inspire

  • Coach, mentor, and develop site staff to reach their highest potential and operate as a cohesive, high-performing team
  • Establish a culture of ownership, accountability, and continuous improvement
  • Champion patient experience, retention strategies, and enrollment excellence

Drive Performance

  • Own site-level KPIs, including enrollment targets, financial performance, and quality metrics
  • Implement and optimize operational systems and workflows to improve efficiency and outcomes
  • Collaborate with the Business Development team and Sponsors/CROs to ensure the site has a consistent pipeline of awarded studies

Own the Financials

  • Oversee financial performance across trials
  • Maintain accountability for invoicing accuracy and financial forecasting

Who You Are

You’re a proven clinical research professional with leadership instincts, financial acumen, and the resilience to lead through change. You approach evolving operations with confidence and optimism, recognizing their potential to become success stories under strong leadership.

 

Requirements:

  • Bachelor’s degree required
  • 3+ years of experience in clinical trials (as a primary study coordinator, project coordinator, or similar role)
    • Previous experience at the site-level required
  • 3+ years of people management experience within the healthcare industry required
    • Experience with change management techniques highly valued
  • Strong understanding of clinical trial operations and site-level financials

What Sets You Apart

  • Highly detail-oriented with exceptional organizational skills
  • Strong critical thinker who can prioritize, problem-solve, and execute under pressure
  • Comfortable managing multiple priorities without losing sight of the big picture
  • Tech-savvy with strong computer and reporting skills
  • Clear, confident communicator with the ability to build trust across teams and external partners
  • Customer- and patient-focused mindset

Why This Role Matters

This is a rare opportunity to step into a leadership role where your impact will be visible, measurable, and meaningful. You’ll have the chance to stabilize, grow, and ultimately redefine what success looks like for a clinical research site—and for your own career.

If you’re ready to lead with purpose, drive results, and build something better, we’d love to meet you.

 

 

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