Back to jobs

Finance Systems Manager

South San Francisco, CA

The Opportunity

insitro is a drug discovery and development company using machine learning and data generation at scale to transform the way that drugs are discovered and delivered to patients. A strong environment of efficient and effective business systems are vital for our day to day procurement operations to help deliver on this mission, as well as ensure we're able to report financial information accurately and timely.

insitro is seeking a dynamic and forward-thinking Finance Systems Manager to join our team reporting to the Director of Procurement. This role is pivotal to driving strategic digital transformation by building and optimizing an integrated Accounting, Finance, Inventory Management and Procurement reporting systems infrastructure delivering sustainable competitive advantages in Life Sciences. You will lead initiatives bridging business strategy, various systems and technologies, enabling data-driven decisions leading to impactful organizational outcomes. This is a hybrid position with the expectation of working 3 days per week onsite in our South San Francisco office.

If you are passionate about reimagining financial systems, data analytics and reporting, delivering transformational digital impacts and thrive by the challenge of setting industry-leading standards, we want to hear from you!

Your key responsibilities will include:

Systems Infrastructure & Automation

  • Own and lead all facets of Oracle Cloud Fusion, driving interconnectivity, automation, and efficiency.
  • Manage relationships with Oracle managed service providers, ensuring seamless technical fixes and system maintenance.
  • Conduct root-cause analysis, implement resolutions, and document findings to improve long-term system performance.
  • Collaborate with stakeholders to gather and document near- and long-term requirements for Finance and business needs.
  • Oversee systems integration across boundaries, ensuring smooth data flow and alignment.
  • Lead system refreshes, quarterly release innovation reviews, and timely implementation of updates and enhancements.
  • Build and enable business intelligence systems, including analytics dashboards that deliver actionable insights across Finance and supporting units.
  • Spearhead end-to-end project management for system enhancements, from gathering business requirements to testing, stabilization, and adoption.
  • Provide technical support for end-users, resolving high-priority tickets and production issues with a focus on root-cause resolution.
  • Analyze current processes and systems, recommending and implementing best-practice improvements.

Stakeholder Engagement & Project Management

  • Deliver technology thought leadership across functions to drive digital transformation and enhance systems adoption.
  • Employ formal change management methodologies to ensure high ROI from system enhancements.
  • Support critical initiatives for SOD (Segregation of Duties) and SOX compliance in partnership with the Accounting team.
  • Collaborate with Finance teams to optimize and automate processes such as supplier punch-outs and cash reconciliation.

Strategic Vision & Innovation

  • Partner with leadership to design and execute a long-term, forward-looking Finance systems strategy aligned with insitro's business goals.
  • Act as a thought leader to drive best practices, foster innovation, and implement holistic, integrated financial technology ecosystems.
  • Develop a strategic five-year roadmap emphasizing automation, integration, and continuous improvement of Finance-critical systems.

About You

  • 8+ years of progressive experience in a business and financial technologies with a demonstrable track record of strategic impact
  • Agile mindset capable of delivering needle-moving results across many concurrent projects
  • Visionary systems expert with a passion of integrating strategy, technology and innovation to design and implement transformative technology infrastructure
  • Bachelor's in Accounting, Finance, Business Administration, IT, Computer Science, Engineering or similar related field
  • Oracle ERP functionality expertise required. Experience using Oracle reporting tools (OTBI, SmartView, FRS)
  • Knowledge of procure-to-pay, Accounting close and general Accounting/Finance practices
  • Proficient in business intelligence and data visualization tools (Tableau)
  • Outstanding project management and business partnering
  • Empathetic approach to technology design, implementation and change management
  • Comprehension of SOX and audit practices

Nice to Have

  • Life Sciences experience
  • Experience with Anaplan, UKG, and Jira or comparable systems

Compensation & Benefits at insitro

Our target starting salary for successful US-based applicants for this role is $165,000 - $185,000. To determine starting pay, we consider multiple job-related factors including a candidate's skills, education and experience, market demand, business needs, and internal parity. We may also adjust this range in the future based on market data.

This role is eligible for participation in our Annual Performance Bonus Plan (based on company targets by role level and annual company performance) and our Equity Incentive Plan, subject to the terms of those plans and associated policies.

In addition, insitro also provides our employees:

  • 401(k) plan with employer matching for contributions
  • Excellent medical, dental, and vision coverage as well as mental health and well-being support
  • Open, flexible vacation policy
  • Paid parental leave of at least 16 weeks to support parents who give birth, and 10 weeks for a new parent (inclusive of birth, adoption, fostering, etc)
  • Quarterly budget for books and online courses for self-development
  • Support to attend professional conferences that are meaningful to your career growth and role's responsibilities
  • New hire stipend for home office setup
  • Monthly cell phone & internet stipend
  • Access to free onsite baristas and cafe with daily lunch and breakfast for employees who are either onsite or hybrid
  • Access to free onsite fitness center for employees who are either onsite or hybrid
  • Access to a free commuter bus and ferry network that provides transport to and from our South San Francisco HQ from locations all around the Bay Area

insitro is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

We believe diversity, equity, and inclusion need to be at the foundation of our culture. We work hard to bring together diverse teams–grounded in a wide range of expertise and life experiences–and work even harder to ensure those teams thrive in inclusive, growth-oriented environments supported by equitable company and team practices. All candidates can expect equitable treatment, respect, and fairness throughout the interview process.

#LI-Hybrid

About insitro
 
insitro is a drug discovery and development company using machine learning (ML) and data at scale to decode biology for transformative medicines. At the core of insitro’s approach is the convergence of in-house generated multi-modal cellular data and high-content phenotypic human cohort data. We rely on these data to develop ML-driven, predictive disease models that uncover underlying biologic state and elucidate critical drivers of disease. These powerful models rely on extensive biological and computational infrastructure and allow insitro to advance novel targets and patient biomarkers, design therapeutics and inform clinical strategy. insitro is advancing a wholly owned and partnered pipeline of insights and therapeutics in neuroscience, oncology and metabolism. Since launching in 2018, insitro has raised over $700 million from top tech, biotech and crossover investors, and from collaborations with pharmaceutical partners. For more information on insitro, please visit www.insitro.com.

Apply for this job

*

indicates a required field

Resume/CV*

Accepted file types: pdf, doc, docx, txt, rtf

Cover Letter

Accepted file types: pdf, doc, docx, txt, rtf

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in insitro’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

Select...
Select...
Race & Ethnicity Definitions

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Select...

Voluntary Self-Identification of Disability

Form CC-305
Page 1 of 1
OMB Control Number 1250-0005
Expires 04/30/2026

Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

  • Alcohol or other substance use disorder (not currently using drugs illegally)
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
  • Blind or low vision
  • Cancer (past or present)
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or serious difficulty hearing
  • Diabetes
  • Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
  • Epilepsy or other seizure disorder
  • Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
  • Intellectual or developmental disability
  • Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
  • Missing limbs or partially missing limbs
  • Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
  • Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
  • Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
  • Partial or complete paralysis (any cause)
  • Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
  • Short stature (dwarfism)
  • Traumatic brain injury
Select...

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.