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Director/Senior Director, Head of Medical Affairs

Hybrid - US

About Us

Jnana Therapeutics is a clinical-stage biotechnology company leveraging its next-generation RAPID chemoproteomics platform to discover medicines for highly validated, challenging-todrug targets to treat diseases with high unmet needs. Jnana is focused on developing first- and best-in-class therapies to treat a wide range of diseases, including rare diseases and immune mediated diseases. Jnana’s wholly owned lead program, JNT-517, which targets an allosteric site on the phenylalanine transporter SLC6A19, is a potential first-in-class oral approach for the treatment of PKU, a rare genetic metabolic disease. Located in Boston, Jnana brings together scientific leaders in small molecule drug discovery and development, a highly experienced management team, and the backing of leading life science investors Bain Capital Life Sciences, RA Capital Management, Polaris Partners, Versant Ventures, Avalon Ventures, Pfizer Ventures, and AbbVie Ventures. For more information, please visit www.jnanatx.com and follow us on Twitter/X and LinkedIn.

At Jnana, you join a diverse, ambitious, and passionate team dedicated to making substantial advancements for patients across a variety of diseases. The culture at Jnana is one of collaboration and urgency, driven by a shared purpose to deliver innovative therapies for the most challenging targets. Our team's quality and the cutting-edge nature of our science are what make Jnana a great place to work every day – and a place where you belong!

About the Opportunity

Join our dynamic team at Jnana Therapeutics, a pioneering biopharmaceutical company dedicated to advancing first-in-class therapies that address critical unmet medical needs through innovative science and strategic collaboration. As the Head of Medical Affairs reporting to the Head of Development, you will play a pivotal leadership role in shaping and executing the medical strategy to support our therapeutic portfolio.

In this key position, you will have the opportunity to build and lead the Medical Affairs function, driving the development and implementation of medical strategies aligned with our innovative pipeline. Leveraging our highly matrixed and collaborative team environment, you will establish and nurture relationships with key opinion leaders, healthcare professionals, and internal stakeholders to drive scientific exchange and support evidence-based medicine.

Responsibilities

  • Develop and execute comprehensive medical affairs strategies, including scientific communication plans, medical education initiatives, and evidence generation activities to support product development and market access.
  • Align medical plans and activities with global business and commercial strategy while ensuring compliance with global and regional areas codes of practice.
  • Build and lead a high performing medical team to support engagement with medical communities and patients, clinical trial recruitment and information dissemination.
  • Engage with advocacy groups and engage with patient communities to establish Jnana as a trusted partner within the patient community. Work to build relationships with patient groups and highlight opportunities for clinical trial enrollment.
  • Serve as a scientific and medical expert and spokesperson for our therapeutic areas, engaging with external stakeholders including healthcare providers, and academic institutions. Provide medical and scientific insights to inform clinical development plans, regulatory submissions, and commercial strategies, ensuring alignment with global regulatory standards and healthcare practices.
  • Lead and participate in advisory boards, symposia, and scientific conferences to gather insights, disseminate clinical data, and enhance awareness of our therapeutic innovations.
  • Collaborate closely with cross-functional teams including Clinical Development, Regulatory Experts, and Commercial Operations to integrate medical insights into strategic planning and decision-making processes.
  • Lead the development of scientific publications, medical information resources, and educational materials to support medical education and awareness initiatives.
  • Provide expert knowledge of scientific literature, clinical trial data, and competitive landscape to provide proactive insights and recommendations that contribute to strategic positioning and competitive advantage.

Preferred Qualifications

  • Advanced degree in life sciences, pharmacy, or medicine (MD, PharmD, PhD) preferred with experience in rare disease drug development; other relevant therapeutics areas is a plus.
  • Proven leadership experience in Medical Affairs within the biopharmaceutical industry, with a strong track record of developing and executing impactful medical strategies.
  • Deep understanding of global regulatory requirements, clinical trial design, and medical communication practices.
  • Excellent communication, presentation, and interpersonal skills, with the ability to effectively engage with internal and external stakeholders across different levels and functions.

 

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