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Supply Chain Process & Transformation Lead

Framingham, US

About KalVista Pharmaceuticals, Inc. 

KalVista is a global pharmaceutical company dedicated to delivering life-changing oral therapies for individuals affected by rare diseases with significant unmet needs. The KalVista team discovered and developed EKTERLY®—the first and only oral on-demand treatment for hereditary angioedema (HAE)—and continues to work closely with the global HAE community to improve treatment and care for this disease around the world.

For more information about KalVista, please visit www.kalvista.com and follow us on LinkedIn, X, Facebook and Instagram.

About EKTERLY® (sebetralstat)

EKTERLY (sebetralstat) is a novel plasma kallikrein inhibitor approved in the United States, European Union, United Kingdom and Switzerland for the treatment of acute attacks of hereditary angioedema (HAE) in people 12 years of age and older. EKTERLY is the first and only oral on-demand treatment for HAE, offering efficacious and safe treatment of attacks without the burden of injections. With ongoing studies exploring its use in children aged two to 11 and multiple regulatory applications under review in key global markets, EKTERLY has the potential to become the foundational therapy for HAE management worldwide.

For more information visit EKTERLY.com.

 

About the role:

The Supply Chain Process & Transformation Lead will play a pivotal role in shaping and advancing KalVista’s Global Supply Chain (GSC) organization. This role focuses on process improvement, operational efficiency, and business transformation - helping to build scalable, compliant, and high-performing supply chain operations that support KalVista’s growing clinical and commercial portfolio.

The Supply Chain Process & Transformation Lead will also serve as the project lead for global launch readiness, ensuring alignment across KalVista’s network. This includes orchestrating cross-functional plans, supply readiness activities, and operational execution to enable successful product launches globally. This role will report to the VP, Global Supply Chain.

Responsibilities:

  • Evaluate, design, and optimize end-to-end supply chain processes spanning planning, procurement, manufacturing, logistics, and distribution
  • Define and document global process standards, workflows, and ownership across functions and regions
  • Develop and maintain supply chain KPIs and performance dashboards that drive data-informed decision-making
  • Embed continuous improvement methodologies (Lean, Six Sigma) to increase efficiency, reduce complexity, and strengthen compliance
  • Ensure process governance, change control, and alignment with GxP and audit readiness requirements
  • Lead global and cross-functional transformation initiatives focused on improving operational performance and scalability
  • Partner with key stakeholders to translate strategic goals into executable improvement programs
  • Support business readiness for system enhancements by aligning processes, training, and change management activities
  • Foster a culture of collaboration, accountability, and continuous improvement within the Global Supply Chain team
  • Communicate effectively with Supply Chain Leadership Team on project milestones, risks, and impact
  • Establish consistent performance management frameworks across regions and functions
  • Support S&OP and executive reporting processes with meaningful analytics and insights
  • Identify skill gaps and partner with functional leads to enhance organizational capability and process ownership
  • Promote best-practice sharing across sites and functions to drive global alignment and operational maturity

Qualifications:

  • Bachelor’s degree in supply chain management, Engineering, Life Sciences, or a related field; Master’s preferred
  • Minimum 5+ years in global supply chain, operational excellence, or transformation roles within biotech, pharma, or life sciences
  • Professional certifications such as APICS, Lean Six Sigma, or PMP are advantageous
  • Demonstrated success leading process improvement and transformation initiatives across end-to-end supply chain functions
  • Solid understanding of ERP systems (SAP preferred) and their role in business process enablement
  • Proven track record of cross-functional collaboration and stakeholder influence
  • Experience in GxP or regulated environments is strongly preferred
  • Strategic thinker with strong analytical and problem-solving skills
  • Excellent communication and facilitation abilities across all organizational levels
  • Skilled at simplifying complex processes and building practical, scalable solutions
  • Comfortable leading both structured projects and iterative improvement efforts
  • Hands-on, adaptable, and energized by working in a dynamic, growing biotech environment

 

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

Important Notice to Third-Party Recruiters & Staffing Agencies:

The current job openings advertised on this website are for the sole purpose of candidates to apply directly. Unsolicited and anonymous CVs submitted in any manner to KalVista employees, including to employee personal e-mail accounts, are considered to be the property of KalVista and will not qualify for a fee to be paid. Referral fees will only be payable where KalVista has agreed with an agency to work on a specific appointment, and then only in conjunction with a fully-executed contract for service.

If any Agency representative contacts a KalVista Hiring Manager or company employee, other than a member of the KalVista Talent Acquisition team, to solicit an appointment to engage on a job opening, that Agency will not be considered for that specific job opening or future opportunities with KalVista.

Thank you for your understanding and cooperation.

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