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Sr. Director, Infrastructure, SRE, & Security

United States

We Breathe Life Into Data

At Komodo Health, our mission is to reduce the global burden of disease. And we believe that smarter use of data is essential to this mission. That’s why we built the Healthcare Map — the industry’s largest, most complete, precise view of the U.S. healthcare system — by combining de-identified, real-world patient data with innovative algorithms and decades of clinical experience. The Healthcare Map serves as our foundation for a powerful suite of software applications, helping us answer healthcare’s most complex questions for our partners. Across the healthcare ecosystem, we’re helping our clients unlock critical insights to track detailed patient behaviors and treatment patterns, identify gaps in care, address unmet patient needs, and reduce the global burden of disease. 

As we pursue these goals, it remains essential to us that we stay grounded in our values: be awesome, seek growth, deliver “wow,” and enjoy the ride. At Komodo, you will be joining a team of ambitious, supportive Dragons with diverse backgrounds but a shared passion to deliver on our mission to reduce the burden of disease — and enjoy the journey along the way.

The Opportunity at Komodo Health

The Infrastructure, SRE & Security team is the foundation Komodo's AI platform is built on. We own the cloud, data, and security foundations that enable Product and Engineering to ship with velocity and confidence  from our AI agent runtimes and platform services to customer-facing SaaS products and the data pipelines that power the Healthcare Map. We're looking for a hands-on Head of Infrastructure, SRE & Security to lead a centralized, transversal team through a pivotal moment: Komodo's transformation into an AI-native platform company. You'll own four domains: Cloud Infrastructure, Data Infrastructure, Security Engineering, and Platform/Shared Services and partner closely with AI Engineering, Platform Engineering, and Product leadership.

Komodo is becoming a 100% AI company. Build the infrastructure that makes it possible.

Looking back on your first 12 months at Komodo Health, you will have…

  • Established yourself as the infrastructure leader for Komodo's AI-native era — a trusted partner to the CTO and VP of AI Engineering, ensuring cloud and data infrastructure is purpose-built for our AI platform
  • Delivered measurable cloud cost optimization across AWS and Snowflake through systematic FinOps practices, warehouse rightsizing, and team-level budget accountability
  • Hardened security and compliance posture for an AI-first company — SOC 2 audit-ready, AI-specific security governance in place, and zero critical unresolved vulnerabilities beyond SLA
  • Scaled infrastructure to support our agentic AI platform — reliable Kubernetes infrastructure, fast ephemeral environments, and production-grade IaC coverage
  • Built a high-performing, automation-first team with AI-assisted tooling embedded in day-to-day engineering workflows

You will accomplish these outcomes through the following responsibilities…

  • Own the architecture, reliability, and cost efficiency of Komodo's cloud infrastructure (AWS primary, GCP); drive full IaC coverage and lead Kubernetes operations at scale
  • Own data infrastructure operations, cost governance, and security hardening; partner with Data Product Engineering on modernizing data delivery infrastructure
  • Lead security posture management across cloud, application, and identity layers — vulnerability lifecycle, penetration testing, IAM, SOC 2 compliance, and AI security governance
  • Define and instrument cost-per-unit metrics, implement per-team budgets with automated alerting, and give leadership direct visibility into infrastructure efficiency
  • Operate internal developer platforms with self-service onboarding, CI/CD, and observability infrastructure that improves engineering velocity
  • Own incident response, on-call rotations, and post-mortem processes; drive reduction in preventable operational incidents and maintain high availability SLAs
  • Lead, recruit, and grow a globally distributed team of cloud, data, and security engineers; foster a culture of ownership and technical excellence

What you bring to Komodo Health:

  • 8+ years in infrastructure, SRE, or platform engineering; 3+ years leading teams in an AI/ML-intensive environment
  • Hands-on experience with AI workload infrastructure — LLM serving, agent orchestration, GPU compute, or ML pipelines — and the reliability and cost challenges they introduce
  • Deep AWS and production Kubernetes expertise (EKS, autoscaling, multi-cluster management) and strong IaC discipline (Terraform or equivalent)
  • Demonstrated track record of driving significant cloud cost reduction through systematic FinOps — team-level budgets, cost-per-unit metrics, and leadership-facing dashboards
  • Practical security and compliance experience — cloud posture management, vulnerability lifecycle, IAM, and SOC 2 or equivalent frameworks; comfort in regulated environments
  • Strong executive communication skills — able to translate infrastructure strategy into business outcomes for CTO, Finance, Legal, and Product stakeholders
  • Active user of AI tools in your own workflow; track record of driving AI-assisted automation adoption within your teams

AI Use Expectations..

  • Use AI coding tools (Copilot, Cursor, Claude Code, or equivalent) to accelerate IaC authoring, runbook generation, and infrastructure automation
  • Leverage AI-assisted observability and incident triage to reduce MTTR and surface patterns across system telemetry
  • Evaluate and adopt AI-native DevOps tooling; set the standard for responsible AI use across the team

Additional skills and experience we’d prioritize (nice to have)…

  • Snowflake administration and data infrastructure experience at scale
  • Multi-cloud environment experience (AWS + GCP)
  • Healthcare, life sciences, or regulated industry background
  • Experience with security automation or agentic security workflows
  • Familiarity with data pipeline technologies (Spark, Airflow, Temporal)
  • Experience supporting multi-tenant SaaS infrastructure

#LIRemote

The pay range for each job posting reflects a minimum and maximum range of annual base pay that we reasonably expect to pay for this position within the US. We carefully consider multiple business-related factors when determining compensation, including job-related skills, work experience, geographic work location, relevant training and certifications, business needs and market demands.

 

The starting annual base pay for this role is listed below. This position may be eligible for performance-based bonuses as determined in the Company’s sole discretion and in accordance with a written agreement or plan. This role may also be eligible for equity awards. In addition, this role is eligible for benefits including, but not limited to, comprehensive health, dental, and vision insurance; flexible time off and holidays; 401(k) with company match; disability insurance and life insurance; and leaves of absence in accordance with applicable state and local laws and regulations and company policy. 

San Francisco Bay Area and New York City:

$245,000 - $305,000 USD

All Other US Locations:

$225,000 - $270,000 USD

Komodo's AI Standard

At Komodo, we're not just witnessing the AI revolution – we're leading it. This is a pivotal moment in time, where being first to market with AI transforms industries and sets the bar. We've already established industry leadership in leveraging AI to revolutionize healthcare, and we expect every team member to contribute. AI here isn't optional; it's foundational. We expect you to integrate AI into your daily work – from summarizing documents to automating workflows and uncovering insights. This isn't just about efficiency; it's about making every moment more meaningful, building on trust in AI, and driving our collective success.

Join us in shaping the future of healthcare intelligence.

Where You’ll Work

Komodo Health has a hybrid work model with hubs in San Francisco, New York City, and Chicago. Roles vary — some can be performed from anywhere in the country, others are scoped to a specific region, and some are based near one of our hubs. For hub-based Dragons, we're building intentional in-office rhythms alongside the flexibility that's core to how we work. Whatever your setup, expectations will always be clear before you join.

Equal Opportunity Statement

Komodo Health provides equal employment opportunities to all applicants and employees. We prohibit discrimination and harassment of any type with regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws. 

By submitting your application, you acknowledge that you have read and understand Komodo Health’s Privacy Notice for Employees and Contractors.

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