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Sr. Medical Director

Somerset, New Jersey, United States

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.  

Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.

 

Legend Biotech is seeking Senior Medical Director as part of the Clinical Development team based in Somerset, NJ. 

Role Overview

 The Senior Medical Director has an essential role in the company with significant impact on the development and life cycle of drug development projects, particularly focused on optimizing safety profile of late stage assets. The Senior Medical Director will work closely with partners in Clinical Development, Translational Development, Safety, Regulatory, Medical Affairs, Healthcare Compliance and Legal. Core responsibilities will encompass developing & executing strategy and providing leadership to existing products, particularly helping manage safety and further develop drug products.

Key Responsibilities   

  • Contribute significantly to the clinical strategy outlined in the Global Clinical Development Plan (CDP) for compounds in clinical development or new clinical entities, working closely with clinical development lead and other stakeholders and cross functional teams.
  • Responsible for helping clinical groups understand the role of CAR-T as a new SOC in earlier lines of treatment and interactions with KOLs, thought leaders as well as internal stakeholders
  • Monitoring, evaluation, and interpretation, of evolving safety information both internally and externally on late stage assets
  • Lead company sponsored non-registration trials, lead secondary analyses of primary data (in collaboration with Clinical Development), lead registries, or research involving 3rd Party databases
  • Partner with Medical Affairs & Translational research to evaluate evidence generation opportunities
  • Maintain high level timelines and detailed timelines for all company deliverables related to clinical needs. Effective, consistent & regular tracking of project timelines to allow full transparency to the senior leadership
  • Assure that functional deliverables are completed on time, within budget and according to the highest quality, ethical and professional standards
  • Ability to build effective working relationships, influence, negotiate, and drive organizational engagement. Ability to be flexible and adapt quickly to the changing needs of the organization. Work closely with a key strategic alliance partner for projects that are being jointly developed.​
  • Identify project risks with input from the cross functional teams, and support resolving issues. Ensure that any potential delays are fully mitigated to avoid any delays with full transparency to senior leadership with proactive mindset.
  • Assure that the highest quality, ethical & professional values are demonstrated in all aspects of the teamwork
  • Ensures compliance with corporate policies and procedures, as well as all related healthcare laws and regulations

Requirements

  • MD (with PhD preferred), with 5+ years of experience in pharma or biotech drug development (preferred), or academia
  • Extensive knowledge of drug development and/or experience in more than one functional area such as clinical, med affairs, translational development, regulatory, commercial, safety, etc., to assure broad understanding of pharmaceutical development
  • Prior oncology or malignant hematology experience. Prior cellular therapy experience is needed. Prior myeloma experience is a plus.
  • Experience administering CARVYKTI to patients or other CART experience as well as understand how to manage patients post-CART
  • Knowledge of competitive products and their application
  • Product lifecycle management experience
  • Superior interpersonal skills, & communication skills ensuring full alignment of cross functional teams. Ability to effectively manage conflicts and negotiations while providing impact and influence 
  • Highly collaborative & effective influencing skills and the ability to operate across multiple geographies
  • Strong track record of delivering results through effective team and peer leadership in matrix
  • Excellent leadership & organizational skills, analytical skills, presentation skills, and strong experience in translating medical/clinical information into medical affairs strategies.

#Li-JK1

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The anticipated base pay range is:

$285,906 - $375,253 USD

Benefits:

We are committed to creating a workplace where employees can thrive - both professionally and personally. To attract and retain top talent in a highly competitive industry, we offer a best-in-class benefits package that supports well-being, financial stability, and long-term career growth. Our offerings are designed to meet the diverse needs of our team members and their families, ensuring they feel valued and supported every step of the way. Highlights include medical, dental, and vision insurance as well as a 401(k)-retirement plan with company match that vest fully on day one. Equity and stock options are available to employees in eligible roles, we offer eight weeks of paid parental leave after just three months of employment, and a paid time off policy that includes 15 vacation days, 5 personal days, 5 sick days, 11 U.S. national holidays, and 3 floating holidays. Additional benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs - demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.

EEO Statement

Legend Biotech is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is Legend’s policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by applicable law.

Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. Legend may adjust base salary or other discretionary compensation at any time based on individual, team, performance, or market conditions.

Legend Biotech maintains a drug-free workplace.

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