
Associate Director, Market Access
Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.
Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.
Legend Biotech is seeking an Associate Director, Market Access as part of the Commercial team based in Bridgewater, NJ.
Role Overview
The Associate Director, Market Access will serve as a critical strategic partner at the intersection of commercial access, pricing & contracting, and clinical development. This role is responsible for advancing pipeline pricing strategy, optimizing gross-to-net (GTN) performance for CARVYKTI and future assets, and ensuring that payer and HEOR insights are systematically integrated into Legend’s clinical trial design and evidence generation efforts. The ideal candidate brings deep experience in oncology or specialty cell therapy market access and is equally comfortable engaging with payers, clinical teams, and commercial leadership.
Key Responsibilities
Pipeline Pricing Strategy
- Lead development of evidence-based pricing frameworks for pipeline assets, including next-generation CAR-T programs, incorporating global benchmarks, competitive positioning, and value-based pricing principles.
- Partner with RWE, Medical Affairs, and Clinical Development to support pipeline pricing and reimbursement positioning.
- Conduct scenario analyses and war-gaming exercises to stress-test pricing assumptions against competitive launches, formulary dynamics, and policy changes
- Collaborate with Global Marketing and ex-US teams to align on international reference pricing implications and coordinate global launch sequencing.
Gross-to-Net (GTN) Optimization
- Own commercial GTN modeling and forecasting in with Finance and Contracts & Pricing, maintaining accuracy across rebate, co-pay assistance, 340B, and other discount line items.
Payer Insight Integration into Clinical Development
- Serve as the primary Market Access liaison to the Clinical Development and Medical Affairs teams, ensuring payer evidence requirements are embedded early in trial design.
- Translate payer, P&T committee, and HTA feedback into actionable recommendations for endpoints, comparators, patient populations, and PRO instruments in Phase 1–3 protocols.
- Identify unmet evidentiary needs across current and pipeline assets.
- Lead early payer advisory boards and simulated HTA exercises (e.g., ICER, NICE dossier prep) to pressure-test clinical evidence packages pre-filing.
- Partner with HEOR to design RWE studies, registries, and outcomes tracking programs that support durable formulary positioning post-launch.
Payer Engagement & Stakeholder Management
- Build and maintain senior-level relationships with national and regional payer medical directors and pharmacy directors across commercial and government segments.
- Lead preparation of payer dossiers, value frameworks, and budget impact models for formulary submissions for pipeline assets.
- Support government affairs and policy team on CMS CAR-T reimbursement policy, including MS-DRG, outpatient CAR-T coverage, and Medicare Part B/D implications.
- Represent Market Access at key industry conferences (AMCP, ISPOR, ASCO) and internal leadership reviews.
Requirements
- Bachelor’s degree required; advanced degree (MBA, PharmD, MPH, or PhD) strongly preferred.
- 7+ years of progressive life sciences experience.
- Demonstrated expertise in pricing strategy, GTN modeling, and contracting in life sciences
- Prior experience integrating insights into business decision making
- Strong command of U.S. payer landscape including commercial formulary dynamics, Medicare Part B/D coverage, Medicaid best price, and 340B.
- Proficiency in financial modeling, budget impact analysis, and scenario planning tools.
- Excellent executive communication and presentation skills; ability to distill complex access dynamics for C-suite audiences.
Preferred
- Experience with CAR-T, gene therapy, or other one-time high-cost therapies and the unique reimbursement challenges they present.
- Familiarity with outcomes-based contracting models and episodes of care
- Experience presenting to c-suite leadership
- Existing relationships within access and reimbursement
#Li-JK1
#Li-Hybrid
The base pay range below is what Legend Biotech USA Inc. reasonably expects to offer at the time of posting. Actual compensation may vary based on experience, skills, qualifications, and geographic location. The company reserves the right to modify this range as needed and in accordance with applicable laws.
Other Types of Pay: Performance-based bonus and/or equity is available to employees in eligible roles.
Benefits and Paid Time Off: Medical, dental, and vision insurance as well as a 401(k) retirement plan with a company match that vests fully on day one. We offer eight (8) weeks of paid parental leave after just three (3) months of employment, and a paid time off policy that includes vacation time, personal time, sick time, floating holidays, and eleven (11) company holidays. Additional voluntary benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide voluntary commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs; demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.
Pay Range (Base Pay):
$163,468 - $214,551 USD
Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.
EEO Statement
It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.
Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.
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