Manager, CMC Project Management

About Loyal

Loyal is a clinical-stage veterinary medicine company developing drugs intended to extend the lifespan and healthspan of dogs. Our mission is to help dogs live longer, healthier lives.

We’ve already achieved significant milestones on our path to earning FDA approval for the first lifespan extension drug for any species. We have three products in our pipeline and are on track for FDA conditional approval within the next year.

Loyal is a well-funded startup in growth mode. Our team includes scientists, veterinarians, engineers, operators, and creatives. This role will play a key role in supporting our growth strategies.

This role will report to the Director of CMC, Project Management.

About the role

Loyal is seeking an experienced and strategic Manager of CMC Project Management to support the development of FDA-approved longevity therapeutics. This role will focus on advancing drug substance and drug product programs from development through registration, working cross-functionally with internal teams and external partners. The ideal candidate will bring strong project management capabilities, deep understanding of pharmaceutical development processes, and the ability to align complex CMC activities with broader program goals.

You will be reporting to our Director of CMC, Project Management

Your daily work will include

• Lead and facilitate cross-functional CMC project teams across the full product lifecycle—from development to pre-commercialization.
• Serve as a key liaison between CMC, Program Management, and cross-functional stakeholders to align project strategy, timelines, and deliverables.
• Act as the primary point of contact for project status, risk identification, and resolution strategies.
• Develop, maintain, and monitor integrated project plans, timelines, and key interdependencies using appropriate tools (e.g., Smartsheet, Gantt Charts).
• Manage multiple CMC projects to ensure milestones are met on time and within budget, providing visibility when milestones are at risk.
• Support and represent CMC functions in project teams; coordinate deliverables across formulation, analytical, manufacturing, regulatory, quality, supply chain and full program team members.
• Proactively identify and escalate risks, delays, and scope changes to senior leadership; propose actionable mitigation plans.
• Partner with CMC leadership to drive resolution and manage contingency planning.
• Ensure accurate budgeting and financial tracking; communicate budget variances to Finance and Executive leadership.
• Contribute to long-range planning and resourcing for CMC projects.
• Coordinate with CDMOs and external vendors to ensure timely execution of CMC activities and high-quality deliverables.
• Monitor performance and alignment with project goals and contractual expectations.
• Create and deliver clear, concise dashboards, presentations, and written updates tailored to different stakeholder levels—from technical teams to executive leadership.
• Document and track meeting agendas, minutes, and action items to ensure accountability and alignment.

About you

• Bachelor’s degree in biological sciences or related field; advanced degree preferred. PMP Certification ideal, although not required.
• Minimum of 8 years’ experience in pharmaceutical industry, with at least 3 years in project management (or equivalent combination of education and experience).
• Proven experience with drug substance and drug product development and commercialization, with a focus on oral solid dosage forms. Experience with other dosage forms is ideal.
• Deep understanding of CMC processes across development stages and regulatory expectations.
• Strong grasp of project management methodologies and tools (e.g., Gantt charts, Smartsheet, PowerPoint, SharePoint).
• Proficient in Google Suite preferred.
• Exceptional organizational, problem-solving, and risk-management skills.
• Excellent written and verbal communication skills; able to convey technical and strategic information across organizational levels.
• Demonstrated ability to think critically, anticipate challenges, and proactively develop solutions.
• Commitment to quality, integrity, and ethical conduct in pharmaceutical R&D and commercialization.

Loyal benefits

• Full-coverage health insurance — medical, dental and vision — for you and your dependents
• $1,000 home office equipment stipend
• $1,200/year learning budget for books, courses, etc.
• $250/month wellness budget for gym, cleaners, spa, food, etc.
• All 3-day weekends are turned into 4-day weekends 🎉
• Unlimited vacation and paid holidays
• Paw-ternity leave — adopt a dog and get a day off with your new family member 🐶
• Annual company retreat at beautiful locations across the country (recently: Tahoe, Cape Cod)
• Competitive salary
• Company equity options grant for new hires

Salary Range: $112,000 - $168,000

Loyal is founded and led by a first-gen female CEO and is proud to be an equal opportunity employer. We do not discriminate against applicants based on gender, race or color, ethnicity or national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or any other applicable characteristics protected by law. 

Our values

Lean into moonshots

We don’t settle for incremental change. We have the bravery to take risks and shoot for the impact we want to have.

Opportunity is at the intersection

We lean into combining disciplines, expertises, and perspectives not normally adjacent. We design our organization to facilitate cross-pollination and cross-collaboration. We reject silos.

Expertise without ego

Titles do not determine who has a voice. We work on hard, technical problems and have a ton of fun while at it.

Learning by doing

Our path is novel and many things we are doing have never been done before. We lean into MVPs and are open to unexpected outcomes.

Lead with context

We value leading with context. We equip people with the context and background necessary to make their own decisions and act in the best interest of Loyal. We empower teams to succeed.

Empathy and respect for all life

Our patients are not just numbers. Our work is intentional, thoughtful, and guided by respect for life. We take our responsibility to pets and pet parents seriously.