Automation Software Scientist

Manifold Bio is a dynamic biotech company building a pipeline of  targeted biologics using a novel in vivo-centric discovery approach. Our drug discovery engine is differentiated by massively parallel screening in vivo from the beginning of our discovery process. This unique platform is powered by a proprietary protein barcoding technology that allows multiplexed protein quantitation at unprecedented scale and sensitivity. We combine this and other high-throughput protein engineering approaches with computational design to create antibody-like drugs and other biologics. Our world-class team of protein engineers, biologists, and computational scientists are working together to aim the platform at therapeutic opportunities where precise targeting is the key to overcoming clinical challenges.

Manifold Bio is a biotech company pursuing a pipeline of protein therapeutics using novel molecular measurement technologies and library-guided protein engineering. Our drug discovery engine is differentiated by massively parallel screening in vivo from the beginning of our discovery process. This unique platform is powered by a proprietary protein barcoding technology that allows multiplexed protein quantitation at unprecedented scale and sensitivity. We combine this and other high-throughput protein engineering approaches with computational design to create antibody-like drugs and other biologics. Our world-class team of protein engineers, biologists, and computational scientists are working together to aim the platform at therapeutic opportunities where precise targeting is the key to overcoming clinical challenges.

Position

Manifold Bio is seeking an exceptional Automation Software Scientist to join our team. This role will lead the development of the software infrastructure supporting complex automation workflows from DNA design, protein expression, protein engineering assays and more. This role will work closely with researchers across the entire Shuttle Discovery group to enable complex operations with software. In particular, core Manifold proprietary assays will be supported directly by this work including mCodes protein barcoding and phi-seq phage-based antibody library affinity characterization. This role will work closely with the Head of Automation, Platform Leads, and the CTO to identify opportunities to expand and integrate operations within a global Discovery Automation Workflows framework. Competitive candidates for this role will have expertise in the life sciences and experience with Benchling. The ideal candidate will have experience implementing automation workflows from previous roles.

Responsibilities

• Work closely with Manifold’s Shuttle Discovery team  to identify and deploy automated workflow solutions particularly focused around assay worklists and metadata integration
• Create tools and frameworks for standard operations leveraging automated tools
• Create interfaces for researchers to execute workflows
• Present and report on latest infrastructure and workflow updates to the team
• Own interfaces and integrations with partner services, including Benchling

Qualifications

• 5+ years of relevant programming experience (including Python)
• Demonstrated and proven experience modeling and building data solutions (e.g. Postgresql)
• Experience developing, orchestrating and supporting workflow pipelines
• Cloud computing experience with Amazon Web Services (AWS)
• Experience across multiple operating systems: Unix/Linux, Mac, and [tolerance of] Windows 
• Detail-oriented with excellent problem identification and problem-solving skills
• Demonstrated ability to work both independently and as part of a team
• A deep passion for automation workflows to support wet lab research
• PREFERRED: master’s or PhD degree, project management experience, relevant certs in data science or project management
• PREFERRED: direct experience working with automation systems such as liquid pipetting robots

If you’re excited to build a platform that combines these technologies to revolutionize how protein therapeutic discovery happens, please reach out to careers@manifold.bio.

We value different experiences and ways of thinking and believe the most talented teams are built by bringing together people of diverse cultures, genders, and backgrounds.