Senior Software Engineer
POSITION SUMMARY:
As a Senior Software Engineer, you will design, build, and evolve scalable, cloud-native, full-stack systems that support Natera’s operational platforms and data workflows for genetic testing.
You will work closely with product managers, operational stakeholders, architects, and other engineers to deliver reliable, secure, and extensible software that supports complex laboratory processes from order to result.
This role includes responsibility for both modern services and critical legacy applications. While some systems are built on a Java-based LIMS platform (LabVantage), the long-term focus of this position is on general software engineering excellence, microservice-based architectures, cloud infrastructure, and modern development practices, rather than deep specialization in a single vendor system.
PRIMARY RESPONSIBILITIES
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Lead the design and implementation of complex backend services and full-stack applications
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Translate business and operational requirements into scalable, maintainable, and reliable technical solutions
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Drive system and service-level design decisions, including trade-off analysis and long-term architecture considerations
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Design and build microservice-based architectures, including REST APIs and event-driven integrations
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Build and operate services deployed on AWS, using Docker and Kubernetes
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Integrate internal services with external enterprise systems to enable seamless end-to-end workflows
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Learn, support, and incrementally modernize legacy systems, including Java-based LIMS applications, while reducing technical debt
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Promote reuse of existing platforms, services, and frameworks where appropriate, while identifying gaps that require custom solutions
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Establish and enforce engineering best practices through code reviews, design reviews, and mentorship
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Improve development processes, tooling, and standards across the team
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Develop and maintain automated tests to ensure system reliability and quality
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Participate in production support, incident response, and root cause analysis
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Ensure systems meet security, compliance, and reliability requirements, including those involving regulated data
QUALIFICATIONS
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Bachelor’s degree in Computer Science, Engineering, or equivalent practical experience
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7+ years of professional software development experience, including ownership of production systems
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Strong experience with Java, plus experience with or openness to working in other modern languages such as Python, TypeScript, or similar
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Proven experience designing and implementing distributed systems and microservice architectures
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Experience with cloud platforms, preferably AWS
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Strong experience designing and consuming RESTful APIs and working with JSON-based data models
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Experience working with databases, including relational databases (Oracle or similar)
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Demonstrated ability to lead technical design and mentor other engineers
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Strong analytical and problem-solving skills
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Excellent written and verbal communication skills
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Commitment to inclusive and collaborative engineering practices
KNOWLEDGE, SKILLS, AND ABILITIES
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Advanced understanding of object-oriented programming and software design principles
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Backend development using Java and modern frameworks (e.g., Spring)
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Working knowledge of additional modern languages such as Python or TypeScript
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REST APIs and service-oriented or microservice architectures
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Relational database design and SQL (Oracle preferred)
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Familiarity with cloud-native data stores and distributed data patterns
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AWS services and cloud infrastructure fundamentals
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Containerization (Docker) and orchestration (Kubernetes)
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CI/CD, automated testing, and production-quality engineering practices
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Strong quality, security, and reliability mindset
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Nice to have: experience working in regulated environments
NICE TO HAVE
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Experience with Kubernetes and operating containerized services in production
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Experience with cloud-native databases (e.g., Aurora, DynamoDB, Redshift)
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Experience with modern frontend frameworks (React, Angular, etc.)
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Experience with CI/CD pipelines, infrastructure-as-code, and deployment automation
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Familiarity with LabVantage or other LIMS platforms
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Experience integrating or extending commercial off-the-shelf enterprise systems
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Experience in healthcare, life sciences, or other regulated environments
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Experience modernizing or migrating legacy systems
Remote USA
$137,500 - $171,900 USD
OUR OPPORTUNITY
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Link: https://www.natera.com/notice-of-data-collection-california-residents/
Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page
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